Understanding Lupus: Key Symptoms, Diagnosis, and Treatment Options
Systemic lupus erythematosus (SLE) Hello, doctor. I started experiencing hair loss (alopecia areata) and urticaria in May of this year. I recalled that four years ago, I had a similar condition and underwent testing in the immunology department, where my anti-dsDNA level was 11. ...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my responses: 1. ANA 1:1280; anti-dsDNA 13; C3 90. The doctor mentioned that although these indices suggest a high likelihood of systemic lupus erythematosus (SLE), since it hasn't reached 15, it cannot be definitively diagnosed...[Read More] Understanding Lupus: Key Symptoms, Diagnosis, and Treatment Options
Managing Lupus: Weight Loss, Muscle Cramps, and Tattoo Safety
Systemic lupus erythematosus (SLE) Hello Doctor: 1. I am a patient with Systemic Lupus Erythematosus (SLE). I would like to ask if it is normal for me to feel very hungry and eat four to five meals a day, despite having a light diet, while still losing weight after being diagnos...
Dr. Gao Jiankai Reply:
Hello, thank you for your questions. Here are my responses: 1. I am an SLE (Systemic Lupus Erythematosus) patient. I would like to ask if it is normal for me to feel very hungry and eat four to five meals a day, even though I have been eating a light diet and have been on medica...[Read More] Managing Lupus: Weight Loss, Muscle Cramps, and Tattoo Safety
Understanding Lupus Nephritis: Key Questions About Diagnosis and Recovery
Questions related to lupus erythematosus and kidney biopsy? Hello Dr. Gao, I was diagnosed with systemic lupus erythematosus (SLE) in 2012, and recently underwent a kidney biopsy that confirmed class III lupus nephritis. I have some questions related to lupus and the kidney bio...
Dr. Gao Jiankai Reply:
Hello, thank you for your questions. Here are my responses: 1. If the biopsy results indicate Class III lupus nephritis, is it possible for treatment to reduce it to Class I or II lupus nephritis, or even to have no nephritis at all? --> The classification may change, but the...[Read More] Understanding Lupus Nephritis: Key Questions About Diagnosis and Recovery
Understanding Abnormal Complement Tests and Their Link to Immune Disorders
Complement test abnormalities in autoimmune diseases? Hello Doctor: Recently, I have been experiencing symptoms resembling urticaria, and I underwent an examination at the rheumatology and immunology department. The test results showed abnormalities: CH50 Assay: 40.7, C3: 74.3, C...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Here are my responses: 1. Is there a possibility of SLE (Systemic Lupus Erythematosus)? --> Based on the information currently provided, the likelihood remains low. 2. Is there a possibility that the immune system is already compromised? -...[Read More] Understanding Abnormal Complement Tests and Their Link to Immune Disorders
Managing Mood Swings and Infections in SLE Patients: A Guide
The SLE patient became manic and developed an abscess on the buttocks after changing medication? Hello Doctor: I am a patient with Systemic Lupus Erythematosus (SLE), currently experiencing stage three nephritis and recurrent vasculitis of the skin. My current medications include...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. The susceptibility to skin infections is indeed related to the current use of immunosuppressants. You may ask your physician to gradually taper your medication based on your condition. Additionally, it is important to protect your skin from inju...[Read More] Managing Mood Swings and Infections in SLE Patients: A Guide
Managing Lupus-Related Kidney Disease: Symptoms, Treatments, and Lifestyle Tips
Systemic lupus erythematosus complicated by class IV lupus nephritis? My husband was diagnosed with systemic lupus erythematosus (SLE) and developed class IV lupus nephritis after a biopsy last October. The rheumatologist recommended hospitalization for treatment. Initially, he h...
Dr. Lin Wuxuan Reply:
Please follow the medical advice provided. If new symptoms or other concerns arise, please return for consultation with the attending physician in the Rheumatology and Immunology department. Thank you.[Read More] Managing Lupus-Related Kidney Disease: Symptoms, Treatments, and Lifestyle Tips
Understanding SLE: Symptoms, Diagnosis, and Treatment Options
SLE (Systemic Lupus Erythematosus) Hello, Director Gao. I am 33 years old and have been experiencing various illnesses and unexplained pains over the past few years, but no cause has been identified. I have also consulted a psychiatrist and taken medication without improvement (s...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. A slight fever can still be concerning, and I recommend visiting a rheumatologist. Based on the information you provided, it is not possible to confirm whether there is an issue with your immune system, so it would be best for a physician to exa...[Read More] Understanding SLE: Symptoms, Diagnosis, and Treatment Options
Understanding SSA Antibodies: Implications for Pregnancy and Lupus Risk
Detection of SSA antibodies? Hello, Doctor. I would like to ask about experiencing unexplained pain and swelling in 1-2 joints of my fingers and toes this year, which disappears after a few days, only to reappear in other areas with tenderness upon pressure. I visited the rheumat...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. The presence of SSA antibodies is not related to the ability to conceive; however, there is still a possibility that Sjögren's syndrome may evolve into lupus erythematosus in the future, although the likelihood is unclear. Therefore, when ...[Read More] Understanding SSA Antibodies: Implications for Pregnancy and Lupus Risk
Understanding Abnormal ANA and Complement Levels: Causes and Next Steps
Antinuclear antibodies and abnormalities in complement levels C3 and C4? Hello Doctor, my wife has had abnormal antinuclear antibody (ANA) levels in her blood tests over the past few years (both AC-1 and AC-4 are affected), with titers fluctuating between a maximum of 1:320 and a...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. The presence of abnormal ANA along with decreased C3 and C4 levels suggests a higher likelihood of an autoimmune disease. C3 and C4 are produced by the liver, and generally, they increase in response to stress or infection. However, in cases of...[Read More] Understanding Abnormal ANA and Complement Levels: Causes and Next Steps
Exploring Alternative Diagnoses Beyond SLE: A Patient's Journey
Systemic lupus erythematosus (SLE) Four months ago, the patient developed a rash on the skin and underwent numerous immunological tests. The results showed C1q 24.2, C1c 24.2, C3 73, PL-12 (++), WBC 3600, platelet count 129,000, and urine tests were negative. ANA, dsDNA, pANCA, a...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. The examination data you provided is insufficient, so I cannot offer any recommendations based on these results. However, I believe that a negative ANA (antinuclear antibody) test reduces the likelihood of systemic lupus erythematosus and increa...[Read More] Exploring Alternative Diagnoses Beyond SLE: A Patient's Journey
Understanding Immune System Abnormalities: Symptoms and Risks of Sjögren's Syndrome
Abnormalities in the immune system? In the past three years, I have experienced intermittent urticaria on my face. After consulting with a rheumatologist, it was determined that it was caused by an allergy, and I have also been experiencing joint pain (without swelling), low-grad...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. I believe the likelihood of Sjögren's syndrome is high. Although the tear secretion is not at the standard level, it is close to the abnormal threshold. Additionally, with a positive SSA, elevated IgG levels, and joint symptoms, if the sali...[Read More] Understanding Immune System Abnormalities: Symptoms and Risks of Sjögren's Syndrome
Understanding Low C3 Levels During Early Pregnancy: What You Need to Know
Low C3 complement levels? Due to being in the early stages of pregnancy (5 weeks), my doctor had me undergo multiple blood tests, and I just saw the results in my health record. My C3 level is only 87 mg/dL (the normal range is above 90). I already have Sjögren's syndrome, b...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. There are many reasons for a decrease in complement C3 levels. If it was previously normal and has now decreased, it may be related to immune system activation. If you have Sjögren's syndrome, it is indeed possible to have lower complement...[Read More] Understanding Low C3 Levels During Early Pregnancy: What You Need to Know
Is the Black Spot on My Neck a Side Effect of Quinine?
Pigmentation changes caused by quinine use? I have systemic lupus erythematosus and regularly take quinine (1.5 tablets/day). Recently, I noticed an unfamiliar black spot on the right side of my neck, approximately 2x3 cm in size. I'm unsure if this could be a side effect of...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. The pigmentation caused by quinine primarily results in a darker skin tone, and it rarely leads to isolated dark spots. We recommend that you schedule an earlier follow-up appointment. The Allergy, Immunology, and Rheumatology Department at Chan...[Read More] Is the Black Spot on My Neck a Side Effect of Quinine?
Understanding ANA Testing in Relation to Lupus and Allergies
Regarding ANA testing in systemic lupus erythematosus? Hello, around September 2022, I experienced redness and itching on my face and scalp, along with peeling skin and increased hair loss. I also felt fatigued and had difficulty concentrating. However, I did not have joint pain ...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my responses: 1. Although the ANA test result is negative, considering that the butterfly rash appeared in September, which was four months ago, how accurate is this blood test? Can systemic lupus erythematosus (SLE) have a negative ...[Read More] Understanding ANA Testing in Relation to Lupus and Allergies
Understanding Positive ANA and Normal Complement Levels in SLE Concerns
ANA positive homogeneous 1:160+ with normal C3 and C4 complement levels? Hello Doctor: Recently, I developed hives and visited the rheumatology and immunology department. After blood tests, it was found that my ANA was positive with a homogeneous pattern at 1:160. Other tests for...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. A positive ANA (antinuclear antibody) test can occur in healthy individuals as well. To confirm this possibility, we will investigate the reasons for a positive ANA, including the series of tests you mentioned. If these tests return negative res...[Read More] Understanding Positive ANA and Normal Complement Levels in SLE Concerns
Understanding Health Insurance Subsidies for Lupus Patients in Taiwan
System for Health Insurance Subsidies for Lupus Erythematosus / Major Illness / Specific Illness / Special Program Hello, Dr. Gao. I would like to inquire whether patients with systemic lupus erythematosus can apply for major illness or specific illness certification to receive h...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Here are my responses: 1. I would like to ask if patients with systemic lupus erythematosus can apply for catastrophic illness or specific illness certification to receive medication subsidies from health insurance? Or can they apply for a heal...[Read More] Understanding Health Insurance Subsidies for Lupus Patients in Taiwan
Understanding Autoimmune Disorders: Symptoms, Diagnosis, and Treatment
Immune system diseases Hello Doctor, I apologize for the lengthy message. This past March, I experienced a persistent low-grade fever for a month and had blood tests done, which indicated elevated immune system markers suggesting rheumatoid arthritis. I was then referred to a r...
Dr. Gao Jiankai Reply:
Hello, thank you for your questions. Here are my responses: 1. Should taking quinine prevent fever? I informed you that I had a fever for a while that day! But if I haven't been examined, which department should I consult to find out where the inflammation is? --> Fever ...[Read More] Understanding Autoimmune Disorders: Symptoms, Diagnosis, and Treatment
Understanding Positive Anti-dsDNA in Young Children with ITP: Key Considerations
When a young child tests positive for anti-dsDNA antibodies, it is important to monitor for potential signs and symptoms of systemic lupus erythematosus (SLE) or other autoimmune disorders. Key considerations include: 1. **Clinical Evaluation**: Conduct Dear Dr. Gao, A toddler ...
Dr. Gao Jiankai Reply:
Hello, thank you for your questions. Here are my responses: 1. I would like to ask, if both the bone marrow aspiration and chromosome tests are normal, but immunoglobulin infusion does not improve platelet counts—initially it was effective but later it failed to raise the platel...[Read More] Understanding Positive Anti-dsDNA in Young Children with ITP: Key Considerations
Understanding Elevated Rheumatoid Factor: What You Need to Know
Elevated rheumatoid factor issue? Hello, Doctor. Last month, at the end of July, I underwent a comprehensive health check-up and unexpectedly found that my rheumatoid factor was elevated (242 IU/ml, with a reference range of below 20 IU/ml). All other health check items were almo...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my responses: 1. The health check report indicates that a small number of healthy individuals may also have elevated RF factors—if I have no symptoms, should I not worry too much? --> Some symptoms can be very mild and may go unno...[Read More] Understanding Elevated Rheumatoid Factor: What You Need to Know
Understanding Hair Loss in Patients with Lupus: Causes and Duration
Hair loss caused by lupus erythematosus? Hello doctor, I have SLE and started taking quinine and corticosteroids in June to manage my condition. Currently, I don't have many symptoms, but I am experiencing severe hair loss. I would like to know if this indicates that my cond...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. If you are feeling well overall but experiencing hair loss, it could potentially be a side effect of quinine. It is advisable to discuss this with your physician. If your SLE (Systemic Lupus Erythematosus) disease activity is currently stable, ...[Read More] Understanding Hair Loss in Patients with Lupus: Causes and Duration