Can You Get Pregnant After One Menopause Shot Without Contraception?

Is it possible to become pregnant after receiving only one dose of a menopause injection without using contraception?

Previously, I naturally conceived and gave birth to a baby boy.
Recently, while preparing for a second pregnancy, I had a follow-up appointment where my CA125 levels were elevated.
On August 1, I received a dose of a menopause-inducing injection to treat adenomyosis and lower my CA125 levels.
I did not use contraception before or after the injection.
By the end of August, my CA125 levels decreased from over 300 to 63.
I took a pregnancy test in early September, which was negative.
It has now been 50 days since the injection, and my menstruation has not arrived.
I would like to know if it is possible to become pregnant during the period after receiving the menopause-inducing injection without using contraception, and if so, would it have any effects on the baby? Thank you.

Le, 30~39 year old female. Ask Date: 2023/09/19

Dr. Cao Guotao reply Obstetrics and Gynecology

Hello, theoretically, you should not be pregnant.
Wishing you good health.

Reply Date: 2023/09/19

More Info

When considering the possibility of pregnancy after receiving a menopause shot, it is essential to understand how these hormonal treatments work and their implications for fertility. The menopause shot, often referred to as a GnRH (gonadotropin-releasing hormone) agonist, is typically used to manage conditions like endometriosis or uterine fibroids by suppressing ovarian function and reducing estrogen levels. This suppression can lead to a temporary state similar to menopause, which can affect ovulation and fertility.

In your case, you received a menopause shot on August 1st, and you have been trying to conceive without using contraception. It is important to note that while the shot is designed to suppress ovarian function, it does not provide immediate or guaranteed contraception. The effects of the shot can vary from person to person, and while many women may not ovulate during the treatment, some may still have residual ovarian activity that could potentially lead to ovulation and conception.

Given that you have not had your menstrual period for 50 days post-injection, it is possible that your body is still responding to the hormonal changes induced by the shot. The absence of menstruation could be a result of the hormonal suppression, but it does not definitively indicate that you cannot become pregnant. If ovulation occurs, and sperm is present, conception could still happen.

Regarding the potential impact on a developing fetus, the safety of becoming pregnant shortly after receiving a menopause shot largely depends on the timing and the specific medication used. Most GnRH agonists are not recommended for use during pregnancy due to the potential risks they pose to fetal development. However, if pregnancy occurs after the effects of the shot have diminished and your body has returned to a more normal hormonal state, the risks may be significantly reduced.

It is crucial to consult with your healthcare provider regarding your specific situation. They can provide personalized advice based on your medical history, the type of menopause shot you received, and your current health status. They may also recommend monitoring your hormone levels and conducting further tests to assess your fertility and the potential risks associated with pregnancy after the shot.

In summary, while it is possible to conceive after receiving a menopause shot without contraception, the likelihood depends on individual factors such as ovarian function and timing. If you suspect you might be pregnant or are considering trying to conceive, it is essential to seek medical advice to ensure the best possible outcomes for both you and any potential future child.

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