Can You Get Pregnant After Chemotherapy-Induced Menopause? - Obstetrics and Gynecology

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Can I get pregnant from unprotected intercourse during the period of amenorrhea caused by chemotherapy?


Hello, doctor! I have undergone chemotherapy due to cancer and have experienced menopause after treatment.
I am currently continuing targeted therapy and taking Novartis medication.
In this situation, if I engage in sexual intercourse and have ejaculation inside, is there a possibility of pregnancy? Will there be any other effects on the patient? Thank you.

Ms. Chen, 30~39 year old female. Ask Date: 2023/11/29

Dr. Lin Manying reply Obstetrics and Gynecology


Hello: The probability of pregnancy is very low, but we cannot guarantee that pregnancy will not occur.
It is recommended to use condoms as an additional precaution.
Hualien Hospital, Ministry of Health and Welfare, cares about your health.

Reply Date: 2023/11/29

More Info


After undergoing chemotherapy, many patients experience menopause due to the effects of the treatment on the ovaries. Chemotherapy can damage the ovarian follicles, leading to a decrease in hormone production and the cessation of menstrual cycles. This condition is often referred to as chemotherapy-induced menopause.
In your case, since you mentioned that you have completed chemotherapy and are currently undergoing targeted therapy while taking Novartis medications, it's important to understand the implications of these treatments on fertility. Generally, if a woman has entered menopause, she is no longer able to conceive naturally. Menopause is defined by the absence of menstrual periods for 12 consecutive months, indicating that the ovaries are no longer releasing eggs.

However, there are some nuances to consider. Some women may experience temporary ovarian suppression due to chemotherapy, which could lead to a return of ovarian function after a period of time. In such cases, it is theoretically possible for a woman to become pregnant if she resumes normal ovarian function. However, this is less common, especially after significant chemotherapy treatment that leads to permanent menopause.

Regarding your question about the possibility of pregnancy through sexual intercourse and ejaculation, if you are indeed in a state of menopause, the likelihood of becoming pregnant is extremely low. However, if there is any uncertainty about your menopausal status, it is advisable to consult with your healthcare provider. They may recommend hormone level testing or other evaluations to confirm whether you are still capable of ovulating.

As for the impact of sexual activity and potential pregnancy on your health, it is essential to consider the medications you are currently taking. Some cancer treatments can have teratogenic effects, meaning they could harm a developing fetus if pregnancy were to occur. Therefore, if there is any chance of pregnancy, it is crucial to discuss contraceptive options with your healthcare team to avoid unintended consequences.

In summary, if you have indeed reached menopause due to chemotherapy, the chances of becoming pregnant are very low. However, if there is any doubt about your ovarian function, it is best to consult with your oncologist or a fertility specialist. They can provide personalized advice based on your medical history and current treatment regimen. Additionally, if you are concerned about the implications of sexual activity while undergoing targeted therapy, your healthcare provider can offer guidance on safe practices and any necessary precautions to take during this time.

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