Can I Take Hiros Capsules on an Empty Stomach Before Bed? - Family Medicine

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I would like to ask if "Yongsheng" Hiros extended-release micro-particle capsules can be taken on an empty stomach before bedtime, or should they only be taken after meals? Will taking them on an empty stomach harm the stomach? Additionally, I would like to know if the medication's effect lasts for 24 hours.
Thank you!

Niming, 20~29 year old female. Ask Date: 2023/09/22

Dr. Lin Zhebin reply Family Medicine


Hello: "Yongsheng" Xi Luo extended-release micro-particle capsules contain two active ingredients: Cetirizine and Pseudoephedrine.

- Cetirizine is an antihistamine primarily used to relieve runny nose.
Possible side effects include dizziness, drowsiness, and dry mouth, among others.
- Pseudoephedrine is a sympathomimetic agent mainly used to relieve nasal congestion.
Possible side effects include palpitations and insomnia, among others.
This medication can be taken on an empty stomach before bedtime; however, it is important to monitor for any occurrences of insomnia.
Additionally, it is not necessary to take it after meals, as taking it on an empty stomach typically does not harm the stomach.
The general recommendation is to take this medication twice a day (once in the morning and once in the evening), so the duration of effect should be around 12 hours.

Reply Date: 2023/09/22

More Info


When considering the use of Hiros capsules (also known as Hiros sustained-release micro-particle capsules) before bed, it's important to understand both the medication's intended use and how it interacts with the body. Hiros is typically prescribed for the relief of allergic rhinitis symptoms, and its formulation is designed to provide sustained release of the active ingredients over a period of time.


Can Hiros Capsules Be Taken on an Empty Stomach Before Bed?
1. Administration Timing: While it is generally recommended to take Hiros capsules after meals to minimize gastrointestinal irritation, taking them on an empty stomach is not strictly contraindicated. However, doing so may increase the risk of gastrointestinal discomfort or irritation, especially if you have a sensitive stomach or a history of gastrointestinal issues.

2. Potential for Gastric Irritation: Taking medications on an empty stomach can sometimes lead to increased gastric acid secretion, which may cause discomfort or exacerbate conditions like gastritis or peptic ulcers. If you have a history of such conditions, it would be wise to avoid taking Hiros capsules on an empty stomach.

3. Best Practices: If you choose to take Hiros capsules before bed, it is advisable to do so with a full glass of water and ideally after a light meal or snack. This can help buffer the stomach and reduce the likelihood of irritation.


Duration of Effectiveness
Regarding the duration of the medication's effectiveness, Hiros capsules are designed for sustained release, which typically means that they can provide relief for up to 24 hours. This sustained-release mechanism allows for a gradual release of the active ingredients into the bloodstream, providing a more consistent therapeutic effect throughout the day.


Recommendations
- Consult Your Physician: Before making any changes to how you take your medication, including the timing and whether to take it on an empty stomach, it is crucial to consult with your healthcare provider. They can provide personalized advice based on your medical history and current health status.

- Monitor for Side Effects: If you decide to take Hiros capsules before bed, pay attention to how your body responds. If you experience any discomfort, nausea, or other gastrointestinal symptoms, consider reverting to taking the medication after meals.

- Consider Alternatives: If you are struggling with nighttime symptoms of allergic rhinitis or other conditions, discuss with your healthcare provider whether there are alternative medications or strategies that might be more suitable for nighttime use.

In summary, while Hiros capsules can technically be taken on an empty stomach, it is generally recommended to take them after meals to minimize the risk of gastrointestinal irritation. The medication is designed to provide relief for up to 24 hours, but individual responses may vary. Always consult with your healthcare provider for tailored advice and to ensure the best outcomes for your health.

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