Left Upper Abdominal Discomfort and Nausea: Could It Be Pancreatitis? - Gastroenterology and Hepatology

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Left upper abdominal discomfort and nausea?


Hello Doctor, I have a duodenal ulcer and have undergone two gastroscopies.
The doctor at the clinic mentioned that there is still a slight ulcer.
Previously, I experienced discomfort primarily in the upper right abdomen, but now, after taking medication for nearly four months, the discomfort has improved.
However, recently, I have started to feel nausea in the left upper abdomen, below the rib cage, although there is no pain.
It is clearly located in the left upper abdomen.
I am still taking ulcer medication, but it hasn't alleviated the nausea.
I would like to know if this could possibly be a symptom of pancreatitis.

A-Hsun, 20~29 year old female. Ask Date: 2023/09/26

Dr. Chen Shidian reply Gastroenterology and Hepatology


Please discuss with the attending gastroenterologist.

Reply Date: 2023/09/26

More Info


When considering left upper abdominal discomfort and nausea, it is essential to explore various potential causes, including pancreatitis, especially given your medical history of duodenal ulcers. Pancreatitis is an inflammation of the pancreas that can manifest with symptoms such as abdominal pain, nausea, vomiting, and changes in bowel habits. However, it is important to note that the presentation of pancreatitis can vary significantly among individuals.

In your case, the discomfort you are experiencing in the left upper abdomen, particularly under the rib cage, could be related to several factors. The pancreas is located in the upper abdomen, but it is situated more towards the back, making it sometimes challenging to pinpoint pain or discomfort in that area. While pancreatitis typically presents with severe, persistent pain that may radiate to the back, your description of nausea without significant pain raises the possibility of other gastrointestinal issues.

Given your history of duodenal ulcers, it is plausible that the discomfort and nausea could be related to your existing condition. Ulcers can cause irritation and inflammation in the gastrointestinal tract, leading to symptoms such as nausea and discomfort. Additionally, medications used to treat ulcers, such as proton pump inhibitors or H2 blockers, can sometimes lead to gastrointestinal side effects, including nausea.

Moreover, the left upper quadrant of the abdomen houses not only the pancreas but also the spleen, stomach, and parts of the colon. Conditions affecting these organs, such as gastritis, splenic issues, or even gastrointestinal reflux disease (GERD), could also contribute to your symptoms. It is also worth considering that stress and anxiety can exacerbate gastrointestinal symptoms, leading to discomfort and nausea.

While pancreatitis is a possibility, it is crucial to rule out other conditions. The absence of severe pain, particularly in the context of pancreatitis, is noteworthy. Typically, pancreatitis pain is acute and severe, often described as a "boring" pain that can be debilitating. In your case, the nausea without significant pain may suggest a different underlying issue.

To further evaluate your symptoms, I recommend discussing your concerns with a gastroenterologist. They may suggest imaging studies, such as an abdominal ultrasound or CT scan, to assess the pancreas and surrounding structures. Blood tests to check for elevated pancreatic enzymes (amylase and lipase) can also help determine if pancreatitis is present.

In summary, while your symptoms could potentially relate to pancreatitis, they may also stem from your history of duodenal ulcers or other gastrointestinal conditions. A thorough evaluation by a healthcare professional is essential to accurately diagnose the cause of your discomfort and nausea. It is important to communicate all your symptoms and medical history to your doctor to facilitate a comprehensive assessment and appropriate management plan.

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