Urticaria recurrence after discontinuation of medication?
Hello, doctor.
Recently, I suddenly started experiencing hives, which have progressively worsened and spread all over my body.
For the past month, I have been taking second-generation antihistamines.
During my consultation, the doctor mentioned that acute urticaria, especially when it appears suddenly, usually resolves with symptom management over time and is less likely to recur, making chronic urticaria less probable.
I have finished my medication, and during the treatment, my symptoms were well controlled, with only occasional mild itching and no raised spots or streaks.
However, two days ago, after finishing the medication, the symptoms of hives began to reappear last night, now sporadically on my thighs and back, with some raised areas at the itchy spots.
I would like to ask if this situation indicates that it might be chronic urticaria, requiring long-term antihistamine treatment to control the symptoms, or should I observe for a few more months? Thank you, doctor.
spec, 20~29 year old female. Ask Date: 2023/10/01
Dr. Li Yufen reply Dermatology
Hello: If hives occur repeatedly for more than 6 weeks, it is more likely to be classified as chronic urticaria.
For a detailed introduction to chronic urticaria, you can refer to the article on MedPartner https://www.medpartner.club/chronic-urticaria-treatment-prevention-introduction/ and Dr.
Chiu-Chia Yu's article https://epaper.ntuh.gov.tw/health/201206/special_1_1.html.
If the skin condition does not improve or worsens, it is recommended to consult a nearby dermatologist for diagnosis and treatment https://www.derma.org.tw/finddoctor/.
Thank you!
Reply Date: 2023/10/01
More Info
Urticaria, commonly known as hives, can be a frustrating and uncomfortable condition. It is characterized by raised, itchy welts on the skin, which can vary in size and can appear anywhere on the body. Understanding whether your urticaria is acute or chronic is crucial for determining the appropriate treatment options.
Acute urticaria typically lasts less than six weeks and is often triggered by an allergic reaction to food, medication, or environmental factors. In contrast, chronic urticaria persists for six weeks or longer and can be more challenging to manage. Chronic urticaria can be idiopathic, meaning the exact cause is unknown, or it can be associated with underlying conditions such as autoimmune disorders, infections, or chronic diseases.
In your case, it seems you have been experiencing a sudden onset of urticaria that has progressively worsened. You mentioned that you have been taking second-generation antihistamines, which are often the first line of treatment for urticaria due to their effectiveness in controlling symptoms with fewer sedative effects compared to first-generation antihistamines. It is encouraging that your symptoms were well-controlled during the course of the medication, with only occasional mild itching.
However, the recurrence of symptoms after stopping the antihistamines raises some important considerations. The fact that you are experiencing new outbreaks of hives, particularly if they are localized and associated with itching, suggests that there may still be an underlying trigger or that your body is reacting to something in your environment.
Here are some recommendations for your situation:
1. Observation Period: Since you have just completed your course of antihistamines and are experiencing a resurgence of symptoms, it may be beneficial to observe your condition for a few weeks. Keep a diary of your symptoms, noting when they occur, their severity, and any potential triggers (such as food, stress, or environmental changes). This information can be invaluable for your healthcare provider.
2. Consider Long-term Antihistamine Use: If your symptoms continue to recur or worsen, it may be necessary to consider long-term use of antihistamines. Chronic urticaria often requires ongoing treatment to manage symptoms effectively. Second-generation antihistamines can be taken daily, and some patients find relief with higher doses than typically recommended, but this should be done under the guidance of a healthcare provider.
3. Consultation with a Specialist: If your symptoms persist or if you experience significant discomfort, it may be worthwhile to consult with a dermatologist or an allergist. They can perform further evaluations, including allergy testing or blood tests, to identify potential triggers or underlying conditions.
4. Lifestyle Modifications: In addition to medication, consider lifestyle changes that may help reduce flare-ups. This includes avoiding known allergens, managing stress, and maintaining a cool environment, as heat can exacerbate itching and hives.
5. Emergency Plan: If you experience severe symptoms, such as difficulty breathing or swelling of the face and throat, seek immediate medical attention, as these could be signs of anaphylaxis, a serious allergic reaction.
In summary, while your symptoms may initially suggest acute urticaria, the recurrence after stopping medication warrants careful monitoring and possibly a longer-term treatment strategy. Consulting with a healthcare provider can help tailor a management plan that suits your needs and alleviates your symptoms effectively.
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