Groin Pain and Iron Deficiency: Insights on Restless Legs - Neurology

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Groin discomfort, iron deficiency, restless legs syndrome, and tightness of the cremaster muscle?


Hello, doctor.
About 4-5 years ago, I underwent laparoscopic surgery for bilateral varicocele.
Approximately 1-2 years post-surgery, I began experiencing a vague, dull pain in the right inguinal region.
I consulted a urologist, and all examination results were normal.
This year, the pain has expanded to the inner thigh, posterior side of the lower leg, and the right testicle, which sometimes experiences spasms and involuntary twitching, especially during thigh flexor stretches, which exacerbates the twitching.
I visited a neurologist for evaluation, and X-rays of the spine were normal, as were the nerve conduction studies.
The doctor initially prescribed Lyrica (pregabalin) and Levofloxacin, which provided significant relief.
Further blood tests revealed iron deficiency, and the doctor suspects it may be restless leg syndrome, so iron supplements were prescribed.
Recently, I have noticed that the dull pain in the inguinal region becomes more pronounced after ejaculation during sexual activity, and the cremaster muscle tends to be more tense and spasmodic.
I searched online for restless leg syndrome but did not find any information regarding these symptoms.
Thank you for your assistance, doctor.

Mr. Chen, 20~29 year old female. Ask Date: 2023/10/08

Dr. Jiang Junyi reply Neurology


Hello Mr.
Chen: You mentioned that "the pain has spread to the inner thigh, posterior lateral side of the right calf, and the right testicle experiences spasms and sometimes involuntary twitching." These symptoms may suggest a neuropathy of the sacral plexus.
Symptoms of peripheral neuropathy include: 1.
Pain characterized by burning or tingling sensations; 2.
Symptoms with a specific dermatomal distribution, which can be triggered by touch or pressure; 3.
Accompanied by muscle soreness and weakness.
You mentioned medications such as Lyrica (pregabalin) and other similar drugs, which can generally alleviate symptoms of nerve instability.
Diagnostic tests for peripheral nerve issues typically include electrophysiological studies.
Nerve conduction studies assess the conduction velocity and waveform of large fiber nerves, while electromyography (EMG) evaluates muscle responses in the affected nerve distribution areas.
I recommend increasing your intake of B vitamins and remind you to stand up and stretch every half hour to avoid nerve compression and muscle tightness that could exacerbate your symptoms.
It would be advisable to consult a neurologist for follow-up examinations, particularly one with expertise in peripheral nerves, as they would have more experience with EMG testing.
Thank you for your inquiry, and feel free to discuss any related questions! Wishing you good health, peace, and joy.
Dr.
Jiang Junyi, Department of Neurology, Taoyuan Hospital, cares about you.

Reply Date: 2023/10/08

More Info


Understanding groin pain, especially in the context of a history of surgery and potential iron deficiency, can be complex. Your situation involves multiple factors, including previous surgery for varicocele, the development of pain in various areas, and the recent diagnosis of iron deficiency, which may contribute to symptoms consistent with Restless Legs Syndrome (RLS).

Firstly, the groin pain you are experiencing could be multifactorial. After undergoing laparoscopic surgery for varicocele, it is not uncommon for patients to experience lingering discomfort or pain in the groin area. This could be due to nerve irritation, scar tissue formation, or changes in blood flow. The fact that your pain has expanded to the inner thigh, back of the thigh, and outer calf suggests that there may be a neurological component involved, especially since you mentioned experiencing spasms and involuntary twitching.

The symptoms you describe, particularly the discomfort that intensifies after sexual activity, could be related to pelvic floor tension or muscle spasms. The pelvic floor muscles can become tight and overactive, leading to discomfort in the groin and surrounding areas. This tension can be exacerbated by anxiety or stress, which is not uncommon in individuals dealing with chronic pain.

Regarding your iron deficiency, it is essential to understand that iron plays a crucial role in various bodily functions, including oxygen transport and muscle function. Low iron levels can lead to fatigue, weakness, and may contribute to symptoms of RLS, which is characterized by an uncontrollable urge to move the legs, often accompanied by uncomfortable sensations. The fact that your doctor has prescribed iron supplements is a positive step, as replenishing iron stores may help alleviate some of your symptoms.

Restless Legs Syndrome can sometimes present with discomfort in the legs, especially during periods of inactivity, and symptoms may improve with movement. However, the specific symptoms you describe, such as the groin pain and testicular spasms, are not classic presentations of RLS. It is possible that these symptoms are related to the previous surgical intervention or other underlying conditions, such as pelvic floor dysfunction or nerve entrapment.

To address your concerns, it would be beneficial to consider a multidisciplinary approach. Here are some recommendations:
1. Physical Therapy: A physical therapist specializing in pelvic floor dysfunction can help assess and treat any muscle tightness or imbalances that may be contributing to your symptoms. They can provide targeted exercises and techniques to relieve tension and improve mobility.

2. Pain Management: Since you have found relief with medications like Lyrica (pregabalin), it may be worth discussing ongoing pain management strategies with your healthcare provider. This could include medication adjustments or alternative therapies.

3. Nutritional Support: Continue with the iron supplementation as prescribed, and consider consulting a nutritionist to ensure you are meeting your dietary needs, which may help improve your overall health and energy levels.

4. Follow-Up with Specialists: Given the complexity of your symptoms, it may be helpful to follow up with both a urologist and a neurologist to rule out any underlying conditions that may be contributing to your pain and discomfort.

5. Monitoring Symptoms: Keep a detailed log of your symptoms, noting when they occur, their intensity, and any potential triggers. This information can be invaluable for your healthcare team in diagnosing and managing your condition.

In conclusion, while your groin pain and associated symptoms may be linked to your surgical history and iron deficiency, a comprehensive evaluation and a multidisciplinary approach will be essential in addressing your concerns effectively. Always consult with your healthcare provider before making any changes to your treatment plan.

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