Can You Get the Flu Vaccine with an Autoimmune Disease? - Internal Medicine

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Influenza vaccine


Hello doctor, I had blood tests this week in the rheumatology and immunology department to check for issues related to my immune system, but the results are not out yet.
My symptoms are suggestive of reactive arthritis.
I would like to ask if it turns out to be an autoimmune disease, would it still be appropriate for me to receive the flu vaccine? Thank you.

Ke, 20~29 year old female. Ask Date: 2023/10/12

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your question.
I believe it is advisable.
Individuals with immune system disorders should also receive the influenza vaccine, and the likelihood of experiencing side effects is not higher.
This is a message from the Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare, caring for you.

Reply Date: 2023/10/12

More Info


Yes, individuals with autoimmune diseases are generally encouraged to receive the flu vaccine. Autoimmune diseases occur when the immune system mistakenly attacks the body’s own tissues, leading to inflammation and damage. Common examples include rheumatoid arthritis, lupus, and multiple sclerosis. While it is understandable to have concerns about vaccination when dealing with an autoimmune condition, the benefits of receiving the flu vaccine often outweigh the risks.

The flu vaccine is designed to help prevent influenza, which can be particularly severe in individuals with compromised immune systems. People with autoimmune diseases may be at a higher risk for complications from the flu, such as pneumonia, hospitalization, or exacerbation of their underlying condition. Therefore, vaccination can be a crucial preventive measure.

Research indicates that the flu vaccine is safe for most individuals with autoimmune diseases. The vaccine does not contain live virus, which means it cannot cause the flu. While some individuals may experience mild side effects, such as soreness at the injection site, fever, or fatigue, these are typically short-lived and much less severe than the flu itself. Importantly, studies have shown that individuals with autoimmune diseases do not have a higher incidence of adverse reactions to the flu vaccine compared to the general population.

It is also worth noting that certain autoimmune conditions may require specific considerations. For example, if you are on immunosuppressive medications, it is essential to discuss your vaccination plan with your healthcare provider. They can provide tailored advice based on your specific condition, treatment regimen, and overall health status. In some cases, timing the vaccine around your medication schedule may enhance its effectiveness.

In summary, if you have an autoimmune disease, getting the flu vaccine is generally recommended to protect yourself from influenza and its potential complications. It is advisable to consult with your healthcare provider, particularly a specialist in rheumatology or immunology, to discuss your specific situation and any concerns you may have. They can help you make an informed decision that aligns with your health needs.

In addition to vaccination, it is also important to practice good hygiene, such as frequent handwashing and avoiding close contact with sick individuals, to further reduce your risk of contracting the flu. Staying informed about your health and maintaining open communication with your healthcare team will empower you to manage your autoimmune condition effectively while taking preventive measures against infections like the flu.

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