Can I Use Biologics for Psoriatic Arthritis with Reactive HBc IgG?
Hello, doctor. I would like to inquire about the use of biologics for psoriatic arthritis? Hello, doctor. I have psoriatic arthritis, and one out of three doctors has applied for a biologic agent for me (currently under review). However, one of my blood test results shows HBc IgG...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. A positive HBc-IgG indicates that you have had a past infection and may still have latent hepatitis B virus. You can still use biologics, but it is important to regularly monitor the hepatitis B virus load to check for any reactivation during tr...[Read More] Can I Use Biologics for Psoriatic Arthritis with Reactive HBc IgG?
Understanding Psoriatic Arthritis: Treatment Options and Concerns
Hello, doctor. I would like to inquire about psoriatic arthritis. Thank you? Hello Doctor, last year I experienced pain in my right wrist and consulted a physician at Kaohsiung Medical University Hospital. The doctor informed me that it might be psoriatic arthritis. I have been t...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my responses: 1. I researched online and feel that my symptoms are very similar to rheumatoid arthritis, but during my initial consultation, the anti-citrullinated protein antibody test came back normal. The doctor said it is not rhe...[Read More] Understanding Psoriatic Arthritis: Treatment Options and Concerns
Understanding Ankylosing Spondylitis Diagnosis and Treatment Options
Diagnosis of Ankylosing Spondylitis Hello, doctor. I am 42 years old and have been experiencing occasional dull pain in my sacroiliac joint for the past six months. I have seen both orthopedic and rehabilitation specialists without any improvement. One day, I woke up at 4 AM due ...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my responses: 1. Am I certain that I have ankylosing spondylitis? --> Currently, the diagnosis of ankylosing spondylitis requires not only blood tests but also clinical symptoms. The absence of nighttime back pain is somewhat unusu...[Read More] Understanding Ankylosing Spondylitis Diagnosis and Treatment Options
Medication vs. Biologics: Which is Better for Ankylosing Spondylitis?
Is it better to take medication or to receive a biologic treatment? Hello Doctor, my son is 20 years old and has been diagnosed with ankylosing spondylitis for 3.5 years. It took 1.5 years after the onset of symptoms to confirm the diagnosis and begin formal treatment. The overvi...
Dr. Zeng Guosen Reply:
The general principle is that traditional oral medications are the first-line treatment. If the condition is stable, the use of biologics is not recommended. It may be worth considering a reduction in medication and monitoring the situation. Biologics are also a type of medicatio...[Read More] Medication vs. Biologics: Which is Better for Ankylosing Spondylitis?
Evaluating Biologics for Ankylosing Spondylitis: A Patient's Dilemma
Should the use of biologic agents be evaluated? Hello, Doctor Gao. My son is 20 years old and has been diagnosed with ankylosing spondylitis for 3.5 years. It took 1.5 years after the onset of symptoms to confirm the diagnosis and begin formal treatment. The overview of his treat...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my responses: 1) Although taking two Salazopyrin and two CellCept daily can effectively manage my child's condition, I am concerned about the potential long-term side effects (such as cardiovascular issues or kidney disease) fro...[Read More] Evaluating Biologics for Ankylosing Spondylitis: A Patient's Dilemma
Can Biologics for Psoriasis Be Used After Prostate Cancer Radiation Therapy?
Can biologic agents for psoriasis be used after radiation therapy for prostate cancer? Hello, my father has been diagnosed with stage II prostate cancer and has undergone radiation therapy. He has been monitored for two years, and his PSA levels are normal. However, due to the im...
Dr. Gao Jiankai Reply:
Hello, thank you for your question. Currently, the use of biologics should be avoided in patients who have been diagnosed with cancer for less than ten years. Different biologics may have varying effects on cancer treatment and recurrence, ranging from significant to minimal impa...[Read More] Can Biologics for Psoriasis Be Used After Prostate Cancer Radiation Therapy?
Impact of COVID-19 Vaccine on Ankylosing Spondylitis: What to Know
The impact of COVID-19 vaccines on ankylosing spondylitis? Hello Doctor, I previously asked you about the worsening of my ankylosing spondylitis condition after receiving the first dose of the BNT vaccine (where my medication became ineffective in controlling inflammation levels ...
Dr. Zeng Guosen Reply:
Hello, the COVID-19 vaccine does not necessarily worsen ankylosing spondylitis; however, it is true that approximately 5% of patients with autoimmune rheumatic diseases may experience instability in their condition after vaccination. The reasons for this are unclear, and the degr...[Read More] Impact of COVID-19 Vaccine on Ankylosing Spondylitis: What to Know
Understanding Biologics for Ankylosing Spondylitis: Key Questions Answered
Biologics Hello, doctor. My son is 18.7 years old and is a patient with ankylosing spondylitis. I would like to ask some questions regarding biologic agents: To save the doctor's time, I would like to define the following conditions as "Condition A" (the prescripti...
Dr. Gao Jiankai Reply:
Hello, thank you for your questions. There are many inquiries, so I can only provide brief responses as follows: 1) If you apply for public funding to receive biologic therapy and it is approved, after a period of treatment, if the inflammatory markers normalize and there is no...[Read More] Understanding Biologics for Ankylosing Spondylitis: Key Questions Answered
Understanding Biologics and Vaccination for Ankylosing Spondylitis Patients
Biologics Hello Doctor, I am currently 19 years old and have ankylosing spondylitis. I received my first dose of the BNT vaccine on September 27, 2021, and I am planning to get the second dose (the delay in receiving the second dose is due to my serious suspicion that the first d...
Dr. Gao Jiankai Reply:
Hello, thank you for your questions. Here are my responses: 1) Is there a regulation on how long one should wait to receive the COVID-19 vaccine before or after receiving a biologic agent? --> Only certain biologic agents require a pause in administration when receiving the C...[Read More] Understanding Biologics and Vaccination for Ankylosing Spondylitis Patients
Evaluating the Efficacy and Risks of Biologics for Ankylosing Spondylitis
Biologics (additional inquiries) The questions below, starting with an asterisk, were previously asked to Dr. Tseng, and I appreciate Dr. Tseng's response on January 25: "It is effective, and I recommend continuing the medication and adjusting the dosage after some time...
Dr. Zeng Guosen Reply:
Hello, the medical guidelines suggest a sequence of medications for treatment, taking into account their side effects and benefits. The principle is to use anti-inflammatory and analgesic medications as the first line of treatment. The consideration of biologics should be discuss...[Read More] Evaluating the Efficacy and Risks of Biologics for Ankylosing Spondylitis
Assessing Long-Term Risks of Biologics vs. Traditional Treatments
Biologics (Follow-up Question) Dear Dr. Gao, Below the asterisks is the question I raised on January 17. I appreciate your detailed response, and I would like to ask a few more questions: 1) I want to focus on the long-term severe (or life-threatening) side effects. The long-te...
Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Here is my consolidated response: 1) I would like to focus on the long-term severe (or fatal) side effects. The long-term severe (or fatal) side effects of Celebrex (celecoxib) include cardiovascular, renal, and gastrointestinal issues. The lon...[Read More] Assessing Long-Term Risks of Biologics vs. Traditional Treatments
Understanding Ankylosing Spondylitis: MRI Findings and Future Implications
Nuclear vibration report issues? Hello Doctor: My son is 19 years old. A year and a half ago, he started experiencing pain in the sacroiliac joint, and recently, through MRI and other examinations, he was diagnosed with ankylosing spondylitis. The following English portion is the...
Dr. Zeng Guosen Reply:
Hello, bone marrow edema indicates a localized inflammatory response. Regardless of whether it is treated or stabilizes on its own, bone marrow edema will resolve, making it reversible. Once healed, there will be residual signs of previous inflammation on the bone, known as subch...[Read More] Understanding Ankylosing Spondylitis: MRI Findings and Future Implications
Effective Treatment Strategies for Ankylosing Spondylitis in Young Patients
Treatment methods My son is currently 18 years old and began experiencing symptoms of ankylosing spondylitis two years ago, with a diagnosis made one year ago. I have the following questions: 1) For the past six months, my son has been taking two capsules of Celebrex (200 mg ea...
Dr. Zeng Guosen Reply:
1) It is effective, and it is recommended to continue taking it while adjusting the dosage over time. 2) Do not consider switching to immunomodulators for now. 3) Only if CRP/ESR remains high after medication can one apply for biologics. 4) SIMPONI is not suitable for children un...[Read More] Effective Treatment Strategies for Ankylosing Spondylitis in Young Patients
Should We Change Medications for Ankylosing Spondylitis Management?
Should the medication be changed? Hello Doctor: My child (born June 2003, currently 18 years and 6 months old) developed ankylosing spondylitis in June 2019 (symptoms only included sacroiliac joint pain, with no morning stiffness). However, he was only diagnosed with ankylosing s...
Dr. Zeng Guosen Reply:
1. At that time, the patient was unable to stabilize their condition with the current medication, so it may be worth trying the new medication recently; if it proves ineffective, we can switch back. 2. It may be worth trying the new medication recently; if it proves ineffective, ...[Read More] Should We Change Medications for Ankylosing Spondylitis Management?
Understanding Ankylosing Spondylitis: Managing Inflammation and Treatment Options
Ankylosing spondylitis has fluctuating levels of inflammation markers? Doctor: A young male, 18 years old, was diagnosed with ankylosing spondylitis at the end of 2020 and started taking Celebrex (200 mg). Below are the CRP (mg/dL) / ESR (mm/hr) and medication records: 2020/11/...
Dr. Zeng Guosen Reply:
1. BNT may lead to instability in certain immune inflammatory diseases. 2. If the ESR is significantly elevated but there are no symptoms, it is advisable to monitor the situation; further investigation should be conducted if abnormalities arise. 3. Disease control includes: ...[Read More] Understanding Ankylosing Spondylitis: Managing Inflammation and Treatment Options
Understanding Diabetes Risk: Interpreting Your Blood Test Results
What is the likelihood of developing diabetes? Hello Doctor, Happy New Year! I would like to ask about my fasting blood test results after 12 hours: Mean Corpuscular Volume (MCV) 78.5, Hemoglobin 24.6, High-Sensitivity C-Reactive Protein (hs-CRP) 10.58, Glycated Hemoglobin (HbA1c...
Dr. Xiao Yongxun Reply:
1. Your fasting blood test report shows an average red blood cell volume of 78.5, hemoglobin of 24.6, high-sensitivity C-reactive protein of 10.58, glycated hemoglobin (HbA1c) of 7.7, GOT (AST) of 86, GPT (ALT) of 172, alkaline phosphatase of 110, total iron binding capacity of 5...[Read More] Understanding Diabetes Risk: Interpreting Your Blood Test Results
Understanding Biologics for Ankylosing Spondylitis: Weight Gain and Edema Concerns
Ankylosing Spondylitis (Biologics) Hello, Doctor: I have ankylosing spondylitis, and since the medication treatment has not been very effective, my physician evaluated my condition and started me on biologic therapy. It has been four months since the treatment began, and I have r...
Dr. Gao Jiankai Reply:
Hello, thank you for your message. Currently, there is no clear evidence indicating that the administration of biologic agents causes edema or weight gain as side effects; in fact, the likelihood of side effects is higher with other medications, particularly anti-inflammatory pai...[Read More] Understanding Biologics for Ankylosing Spondylitis: Weight Gain and Edema Concerns
Understanding the Link Between Rheumatoid Arthritis and Cancer Risk
Rheumatoid arthritis and cancer? 1. What is the relationship between rheumatoid arthritis (RA) and cancer? It is said that RA patients have a higher risk of developing cancer. 2. Some RA patients develop cancer; why is that? Is it influenced by their medical history, disease prog...
Dr. Gao Jiankai Reply:
Hello, 1. The risk of developing cancer seems to be higher in patients with rheumatoid arthritis (RA), particularly for cancers such as lymphoma, which should be monitored during RA follow-up. 2. The evidence linking RA medications to cancer is still unclear. It is currently ...[Read More] Understanding the Link Between Rheumatoid Arthritis and Cancer Risk