Allergy Blood Test Results: Is Your Condition Serious? - Internal Medicine

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Allergy blood test report


I have been coughing for six months, and recently my nasal allergies have been almost daily, so I had blood tests done, but my lung function tests are normal.
The doctor prescribed me an asthma inhaler, and I am hesitant to use it because it contains steroids.
Can you tell me if my levels are serious? The doctor keeps saying I need to use it continuously.
My total IgE is 151, ECP is 112, and the PHADIATOP qualitative result is 4.87 (3).
Is this considered severe allergy? Last year during the change of seasons, it wasn't this bad.
After being diagnosed at the end of May this year, it has been difficult; I have been taking Chinese medicine which helped a bit, but after a while, it started again.

Vivky, 30~39 year old female. Ask Date: 2023/10/30

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your question.
In Eastern populations, asthma often presents primarily as a chronic cough, with typical wheezing being less common.
This may be why your physician prescribed this medication.
Currently, inhaled corticosteroids are the mainstay of asthma treatment, and their side effects are quite low.
By following the medication guidelines, symptoms can significantly improve.
As for the severity of your blood test results, the severity of asthma is not determined by blood tests but rather by the severity and frequency of asthma symptoms.
Blood test results, including ECP, can serve as a follow-up indicator after treatment.
If the treatment is effective, ECP levels will decrease, which can help the physician decide whether to adjust the medication.
The Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare, is concerned about you.

Reply Date: 2023/10/30

More Info


When it comes to understanding allergy blood test results and determining the severity of your condition, it's essential to interpret the numbers in the context of your symptoms and medical history. Based on the information you've provided, let's break down your situation.


Understanding Your Test Results
1. Total IgE (151 IU/mL): Immunoglobulin E (IgE) is an antibody that plays a crucial role in allergic reactions. Elevated levels of total IgE can indicate an allergic response, but the interpretation of this number can vary. Normal IgE levels can range widely depending on age and individual factors, but generally, levels above 100 IU/mL are considered elevated. Your level of 151 IU/mL suggests that you may have an allergic condition, but it does not necessarily indicate the severity of your allergies.

2. ECP (Eosinophil Cationic Protein, 112 ng/mL): ECP is a marker of eosinophil activation, which is often associated with allergic reactions and asthma. Elevated ECP levels can indicate ongoing inflammation in the airways, which is common in asthma and allergic conditions. Your level of 112 ng/mL is elevated, suggesting that there is significant eosinophilic activity, which can correlate with asthma or severe allergic responses.

3. Phadiatop (4.87): This is a specific IgE test that measures sensitivity to common inhalant allergens. A result of 4.87 indicates a positive reaction, suggesting that you have a sensitization to one or more allergens. The number in parentheses (3) likely indicates the reference range, where a higher number suggests a stronger sensitization.


Assessing Severity and Treatment
Given your symptoms of persistent cough and nasal allergies, along with the test results, it is reasonable to conclude that you are experiencing significant allergic reactions, potentially exacerbated by asthma. The fact that your lung function tests are normal is a positive sign, indicating that your airways are not currently obstructed, but it does not rule out asthma or allergic rhinitis.

Your doctor’s recommendation to use inhaled corticosteroids (ICS) is a common approach in managing asthma and severe allergies. While there may be concerns about long-term use of steroids, inhaled corticosteroids are generally considered safe and effective for controlling inflammation in the airways. They can help reduce symptoms and improve your quality of life.


Recommendations
1. Follow Your Doctor's Advice: If your doctor has prescribed inhaled corticosteroids, it is important to discuss any concerns you have with them. They can provide reassurance about the safety and efficacy of the medication.

2. Monitor Your Symptoms: Keep track of your symptoms and any triggers that may worsen your condition. This information can be valuable for your healthcare provider in adjusting your treatment plan.

3. Consider Allergy Testing: If you haven't already, you might want to discuss further allergy testing with your doctor. Identifying specific allergens can help you avoid triggers and manage your symptoms more effectively.

4. Lifestyle Modifications: Implementing lifestyle changes, such as avoiding known allergens, using air purifiers, and maintaining a clean living environment, can also help reduce your symptoms.

5. Regular Follow-ups: Regular check-ups with your healthcare provider are essential to monitor your condition and adjust treatment as necessary.


Conclusion
In summary, your test results indicate that you are experiencing significant allergic reactions, which may be contributing to your respiratory symptoms. While your condition may not be classified as "severe" in a clinical sense, it is certainly impactful on your daily life. Following your doctor's recommendations and maintaining open communication about your treatment will be key in managing your allergies effectively.

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