Medication Consultation for Breastfeeding Moms: Sleep Aids and Safety - Obstetrics and Gynecology

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Consultation on the use of sleep medications during breastfeeding?


Hello, Director Cao! I am a breastfeeding mother, and my child is currently 14 months old.
Recently, the frequency of my child waking up at night for milk has increased, making it difficult for me to fall asleep at night.
I have been experiencing insomnia for over a week! I sought help from a psychiatrist, who informed me that I am currently breastfeeding.
Two psychiatrists prescribed me 0.5 mg of Zyprexa (Olanzapine) and 1.0 mg of Atarax (Hydroxyzine) to take.
However, after researching online, I found that these medications may affect the infant through breast milk, so I have been hesitant to take them.
I would like to ask the doctor: 1.
If medication is absolutely necessary, which is better, 1 mg of Atarax or 0.5 mg of Zyprexa? 2.
Are there other medications that are more suitable for breastfeeding mothers? (Over-the-counter medications are also acceptable) 3.
If I take these medications, what recommendations do you have to minimize the impact on my infant? Thank you very much for your attention and response!

Fang, 40~49 year old female. Ask Date: 2023/10/30

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, the amount of medication that is secreted into breast milk after taking it is generally very small.
If you really cannot sleep, it may be necessary to take it; otherwise, taking care of your child could become an issue.
Wishing you good health.

Reply Date: 2023/10/30

More Info


As a breastfeeding mother experiencing sleep disturbances, it's understandable that you're concerned about the safety of sleep aids and their potential effects on your child. Let's address your questions regarding the medications prescribed to you, as well as provide some general advice on managing sleep issues while breastfeeding.


1. Comparing Medications: Zolpidem (贊安諾) vs. Eszopiclone (悠然錠)
Both Zolpidem (commonly known as Ambien) and Eszopiclone (Lunesta) are non-benzodiazepine sleep aids that are often prescribed for short-term management of insomnia. While both medications can be effective for inducing sleep, they have different pharmacokinetics and potential side effects.

- Zolpidem (贊安諾): This medication has a relatively short half-life, which means it acts quickly and is eliminated from the body fairly quickly as well. However, it can cause next-day drowsiness in some individuals, especially if taken too late at night or if the individual does not get a full night's sleep (7-8 hours). There are concerns about its potential to cause dependence and withdrawal symptoms with long-term use.

- Eszopiclone (悠然錠): This medication has a longer half-life compared to Zolpidem, which may provide a more sustained effect throughout the night. It is also associated with a lower incidence of next-day sedation, making it a potentially better option for those who need to be alert during the day. However, like Zolpidem, it can also lead to dependence if used for extended periods.

Given your situation, if you must choose between the two, Eszopiclone may be preferable due to its longer duration of action and potentially lower risk of next-day sedation. However, this should be discussed with your healthcare provider, who can consider your specific circumstances.


2. Alternative Medications for Breastfeeding Mothers
If you're hesitant to use either Zolpidem or Eszopiclone due to concerns about their effects on your baby, there are other options to consider:
- Melatonin: This is a naturally occurring hormone that regulates sleep-wake cycles. Melatonin supplements are generally considered safe for breastfeeding mothers and can help improve sleep without the sedative effects of prescription medications.

- Doxylamine or Diphenhydramine: These are over-the-counter antihistamines that can induce drowsiness. While they are generally safe for breastfeeding, they can cause sedation in both the mother and the infant, so caution is advised.

- Cognitive Behavioral Therapy for Insomnia (CBT-I): This non-pharmacological approach is highly effective for treating insomnia and can be a great option for breastfeeding mothers. It focuses on changing sleep habits and addressing the thoughts and behaviors that contribute to sleep difficulties.


3. Minimizing Impact on Your Baby
If you decide to proceed with medication, here are some strategies to minimize any potential impact on your breastfeeding infant:
- Timing of Medication: Take the medication right before bedtime to allow for maximum clearance before the next feeding. This can help reduce the amount of medication that might be passed through breast milk.

- Monitor Your Baby: Keep an eye on your baby's behavior and sleep patterns after you start taking the medication. If you notice any unusual drowsiness or changes in feeding patterns, consult your pediatrician.

- Consult Your Healthcare Provider: Always discuss any concerns with your healthcare provider, who can provide personalized advice based on your health history and your baby's needs.


Conclusion
Navigating sleep issues while breastfeeding can be challenging, but there are safe options available. It's essential to weigh the benefits and risks of any medication and to consider non-pharmacological approaches as well. Always consult with your healthcare provider before starting any new medication, and keep an open line of communication regarding your concerns and your baby's health. Your well-being is crucial for both you and your child, and finding a suitable solution is possible with the right support.

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