Uterine Fibroids, Endometriosis, and Pelvic Adhesions: Treatment Options Explained - Obstetrics and Gynecology

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Uterine fibroids, endometriosis, pelvic adhesions?


At 30 years old and unmarried, I am seeking to become pregnant.
I am experiencing painful intercourse and lower abdominal pain a week before my menstrual period.
Currently, I have two fibroids, each over 3.5 cm but not reaching 4 cm, and I have endometriosis and adhesions on the left side.
The doctor provided me with two options:
1.
Take Danazol (Endometriosis medication), which may cause amenorrhea.
I plan to stop the medication in the future when I want to conceive.
The medication will not cure the condition but only manage it.

2.
Undergo laparoscopic surgery with two incisions to remove the fibroids and adhesions.
After the surgery, I will still need to take Danazol for a year to reduce the risk of recurrence.
I would like to know if long-term use of Danazol will cause side effects, and if I choose to have laparoscopic surgery, will I still need to take medication? This aspect is quite confusing for me.

Fang, 30~39 year old female. Ask Date: 2023/11/08

Dr. Lin Xinwang reply Obstetrics and Gynecology


Hello, Fang: After laparoscopic surgery, it is recommended to take medication to reduce pain symptoms and recurrence.
Long-term use of Danazol may lead to abnormal uterine bleeding.

Reply Date: 2023/11/08

More Info


Understanding uterine fibroids, endometriosis, and pelvic adhesions is crucial for women experiencing symptoms such as pelvic pain, heavy menstrual bleeding, and fertility issues. In your case, at 30 years old and seeking to conceive, the presence of two fibroids measuring over 3.5 cm, along with endometriosis and adhesions, presents a complex situation that requires careful consideration of treatment options.


Treatment Options Explained
1. Medication (Visanne):
- Mechanism: Visanne (dienogest) is a progestin that helps manage endometriosis by suppressing the growth of endometrial tissue and reducing associated pain. It can induce a state similar to menopause, which may alleviate symptoms but does not cure the underlying condition.

- Side Effects: Long-term use of Visanne can lead to side effects such as mood changes, weight gain, breast tenderness, and potential impacts on bone density. Some women may experience emotional fluctuations due to hormonal changes, which can be significant if you are already experiencing mood swings.

- Fertility Considerations: While Visanne can help manage endometriosis symptoms, it is not recommended for women trying to conceive. If you choose this route, you will need to stop the medication when you are ready to try for pregnancy, which may lead to a resurgence of symptoms.

2. Surgical Intervention (Laparoscopic Surgery):
- Procedure: Laparoscopic surgery involves making small incisions to remove fibroids and adhesions. This minimally invasive approach can relieve pain and improve fertility by addressing the physical obstructions caused by fibroids and endometriosis.

- Recovery and Follow-Up: Post-surgery, it is common for doctors to recommend continuing hormonal therapy, such as Visanne, for a period (often up to a year) to minimize the risk of recurrence of endometriosis and to help manage any residual symptoms.

- Fertility Outcomes: Many women experience improved fertility after surgery, especially if the fibroids and endometriosis were contributing factors to infertility.


Your Concerns
- Long-Term Use of Visanne: While Visanne is effective in managing endometriosis, long-term use can lead to side effects. It is essential to have regular follow-ups with your healthcare provider to monitor any adverse effects and to discuss your fertility goals.

- Need for Medication Post-Surgery: Even after surgery, continuing medication like Visanne can be beneficial in preventing the recurrence of endometriosis. However, this can be confusing, especially if your primary goal is to conceive. Discussing a tailored plan with your doctor that considers your desire to become pregnant while managing your symptoms is crucial.


Recommendations
1. Consultation with a Specialist: It may be beneficial to consult with a reproductive endocrinologist or a specialist in reproductive medicine who can provide insights into how best to manage your condition while optimizing your chances of conception.

2. Discussing Alternatives: If you are concerned about the side effects of long-term medication, discuss alternative treatments or adjunct therapies that may help manage your symptoms without compromising your fertility goals.

3. Monitoring and Support: Regular monitoring of your symptoms and any side effects from medications is essential. Emotional support, whether through counseling or support groups, can also be beneficial as you navigate these challenges.

In conclusion, both medication and surgical options have their pros and cons, and the best approach often involves a combination of treatments tailored to your specific situation and future fertility plans. Open communication with your healthcare provider will be key in making informed decisions that align with your health goals.

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