Questions about pre-meal blood glucose and glycated hemoglobin?
Hello Doctor, during my health check in 2018, my fasting blood sugar was 105, and in 2022, it was 113, with other results normal.
After undergoing an endoscopy on September 1st this year, I noticed my previous blood sugar readings were concerning, so I asked the doctor to check some items, resulting in two abnormal values: GPT 57 and fasting blood sugar 128.
On September 7th, I had my hemoglobin A1c tested, which was 5.5.
My height is 183 cm, and my weight was 100 kg in January, but on September 1st, it was 95 kg.
The doctor advised me to wait three months for another check-up, suggesting I exercise and change my diet.
Does this mean I have been diagnosed with diabetes? I couldn't find information on having elevated fasting blood sugar but normal A1c levels.
There is no family history of diabetes.
Should I undergo further testing for postprandial blood sugar or an oral glucose tolerance test to assess insulin resistance, or check other items for confirmation in three months? Just thinking about it makes my emotions fluctuate greatly.
I would appreciate your guidance, doctor.
Mr. Hsu, 30~39 year old female. Ask Date: 2023/11/21
Dr. Li Jian reply Internal Medicine
Elevated fasting blood glucose is also a risk factor for diabetes.
It is recommended that you lose weight and continue to follow up at the metabolic clinic.
Thank you for your inquiry.
Reply Date: 2023/11/21
More Info
Based on the information you've provided regarding your blood sugar levels and HbA1c results, it appears that you are currently in a state of prediabetes rather than having a confirmed diagnosis of diabetes. To clarify, let's break down the relevant criteria and your specific results.
According to the American Diabetes Association (ADA), the diagnostic criteria for diabetes include:
1. Fasting plasma glucose (FPG) ≥ 126 mg/dL.
2. 2-hour plasma glucose during an oral glucose tolerance test (OGTT) ≥ 200 mg/dL.
3. HbA1c ≥ 6.5%.
4. A random plasma glucose ≥ 200 mg/dL in a patient with classic symptoms of hyperglycemia or hyperglycemic crisis.
In your case, your fasting blood sugar levels have been slightly elevated, with readings of 105 mg/dL and 113 mg/dL in previous tests, and a more recent reading of 128 mg/dL. However, your HbA1c level of 5.5% is well within the normal range (normal is considered below 5.7%). This discrepancy between your fasting blood sugar and HbA1c suggests that while your fasting glucose is elevated, it is not consistently high enough to meet the criteria for diabetes.
The ADA defines prediabetes as having an HbA1c between 5.7% and 6.4%, or a fasting blood glucose between 100 mg/dL and 125 mg/dL. Since your HbA1c is below 5.7%, you do not meet the criteria for prediabetes either. However, the elevated fasting blood sugar indicates that you should be vigilant about your lifestyle choices, particularly regarding diet and exercise.
Your physician's recommendation to monitor your blood sugar levels over the next three months and to focus on improving your diet and increasing physical activity is sound advice. This approach can help you lower your blood sugar levels and potentially prevent the progression to diabetes.
In terms of further testing, it may be beneficial to conduct a follow-up fasting blood glucose test or an oral glucose tolerance test (OGTT) if your fasting levels remain elevated at your next check-up. These tests can provide additional insight into your glucose metabolism and help assess your risk for developing diabetes.
Regarding your concerns about family history, while having a family history of diabetes can increase your risk, it is not the only factor. Lifestyle factors such as diet, physical activity, and body weight play significant roles in the development of insulin resistance and diabetes.
Lastly, it's important to manage stress and maintain a positive outlook. Emotional well-being can significantly impact your overall health, including blood sugar levels. Engaging in stress-reducing activities such as exercise, meditation, or hobbies can be beneficial.
In summary, while your fasting blood sugar levels are elevated, your HbA1c is normal, indicating that you are not currently diagnosed with diabetes. Continue to monitor your levels, follow your doctor's advice, and make lifestyle changes to maintain your health. If you have further concerns or if your blood sugar levels do not improve, consider discussing additional testing options with your healthcare provider.
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