Blood Donation and HIV Testing: What You Need to Know - Internal Medicine

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Blood Donation and HIV Issues


Hello, my girlfriend has had unprotected sexual intercourse in the past but did not get tested.
Later, she donated blood and received a report stating that her blood was suitable for use (multiplex NAT negative).
However, I saw that the blood donation center mentioned that HIV test results would not be disclosed.
Does this mean that even though the report indicates that her blood is usable, there is still a possibility that she could have HIV? Thank you.

Xin Shui Xiao Gou, 20~29 year old female. Ask Date: 2023/11/22

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your inquiry.
Although AIDS can cause immune dysfunction, AIDS-related diseases are classified as infectious diseases.
Therefore, questions related to AIDS should be directed to the Infectious Disease Department.
Please consult with them.
Thank you! The Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare, cares about you.

Reply Date: 2023/11/22

More Info


When it comes to understanding HIV testing and blood donation, it's essential to clarify several key points regarding the safety of blood donation, the testing methods used, and the implications of test results.

Firstly, it's important to note that blood donation centers typically conduct rigorous testing on donated blood to ensure its safety for transfusion. One of the tests performed is the Multiplex Nucleic Acid Test (NAT), which is highly sensitive and can detect the presence of HIV RNA in the blood. This test is capable of identifying HIV infections earlier than traditional antibody tests, as it can detect the virus within days to weeks after exposure. If your girlfriend's blood was tested and reported as "safe for use" with a negative Multiplex NAT result, it indicates that no HIV was detected at the time of testing.

However, there are a few considerations to keep in mind. The window period for HIV testing varies depending on the type of test used. For instance, while NAT can detect HIV very early, antibody tests may take longer to yield accurate results. If your girlfriend had unprotected sex prior to her blood donation, it is crucial to consider when that exposure occurred in relation to the testing window. If the exposure was recent and within the window period of the test, there is still a possibility that the virus could be present but undetectable at the time of testing.

Regarding the policies of blood donation centers, it is true that they do not routinely inform donors about the results of HIV tests performed on their blood. This is primarily to prevent individuals from using blood donation as a means of personal health screening. Instead, if a donor's blood tests positive for HIV, the blood donation center will typically follow protocols to ensure that the donor is contacted for further testing and counseling, but this process can vary by location.

In your specific case, since your girlfriend's blood was deemed safe for use, it is unlikely that she is HIV positive, especially if the exposure was outside the testing window. However, if there are lingering concerns or if she has had further potential exposures, it would be prudent for her to undergo additional testing. Testing at a healthcare facility can provide more comprehensive results and peace of mind.

Moreover, it is essential to understand that HIV is primarily transmitted through specific routes: unprotected sexual contact, sharing needles, and from mother to child during childbirth or breastfeeding. If your girlfriend has not engaged in any high-risk behaviors since her last test and has received a negative result, the likelihood of her being HIV positive is significantly reduced.

In summary, while the negative Multiplex NAT result is reassuring, it is vital to consider the timing of any potential exposures and the type of testing performed. If there are any doubts or concerns, seeking further testing and consultation with a healthcare provider is advisable. Regular testing and practicing safe sex are crucial steps in maintaining sexual health and preventing the transmission of HIV and other sexually transmitted infections.

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