Benign prostatic hyperplasia, drug interactions?
Hello, doctor! I am currently undergoing treatment for benign prostatic hyperplasia (BPH).
The hospital has prescribed me Doxazosin 0.2 mg, one tablet in the morning and one in the evening, and Tamsulosin 5 mg, half a tablet in the morning and half in the evening.
Can I take Cialis (Tadalafil) 5 mg together with these medications? What should I be aware of?
A-Liang, 50~59 year old female. Ask Date: 2023/11/28
Dr. Du Shixi reply Urology
Hello: You can discuss your situation with your attending physician to see if any action is needed.
Wishing you good health.
Reply Date: 2023/11/28
More Info
When managing Benign Prostatic Hyperplasia (BPH), it is common for patients to be prescribed medications such as alpha-blockers (like Doxazosin, which is the active ingredient in "暢利淨") and 5-alpha-reductase inhibitors (like Finasteride, which may be the active ingredient in "歐舒"). These medications help alleviate symptoms associated with BPH by relaxing the muscles in the prostate and bladder neck, making it easier to urinate.
Cialis (Tadalafil) is a phosphodiesterase type 5 (PDE5) inhibitor that is often used to treat erectile dysfunction and can also help with the symptoms of BPH. The combination of Cialis with medications for BPH can be beneficial, but it is essential to consider potential interactions and side effects.
Safety of Combining Cialis with BPH Medications
1. Mechanism of Action: Cialis works by increasing blood flow to the penis, which can help with erectile dysfunction. It also relaxes the smooth muscles in the prostate and bladder, which can help relieve urinary symptoms associated with BPH. Therefore, combining Cialis with your current medications may provide additional relief from BPH symptoms.
2. Potential Interactions: While there are no direct contraindications for taking Cialis with alpha-blockers like Doxazosin or Finasteride, caution is advised. Both classes of medications can lower blood pressure. When taken together, there is a risk of hypotension (low blood pressure), especially when starting treatment or increasing dosages. It is crucial to monitor your blood pressure regularly.
3. Dosage Considerations: The typical starting dose of Cialis for BPH is 5 mg, which you mentioned. Since you are already on medications for BPH, starting with the lowest effective dose of Cialis is advisable. You should consult your healthcare provider about the appropriate dosage and timing to minimize the risk of side effects.
4. Monitoring Side Effects: When combining these medications, be vigilant for side effects such as dizziness, lightheadedness, or fainting, especially when standing up quickly. These symptoms may indicate that your blood pressure is dropping too low.
5. Consult Your Healthcare Provider: Before starting Cialis, it is essential to discuss this with your healthcare provider. They can provide personalized advice based on your overall health, the severity of your BPH symptoms, and any other medications you may be taking. They may also want to monitor your response to the combination therapy closely.
Conclusion
In summary, combining Cialis with your current BPH medications can be safe and effective, but it requires careful consideration and monitoring. Always consult with your healthcare provider before making any changes to your medication regimen. They can help ensure that you are using the medications safely and effectively to manage your BPH symptoms while minimizing the risk of adverse effects. Regular follow-ups and open communication with your healthcare team are key to successful management of your condition.
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