Blood test report issues?
On August 29, blood tests showed GOT: 75, GPT: 187, HBeAg - EIA Hepatitis B e antigen: 1380.
After continuously taking Viread for about 3 months, on December 1, blood tests showed GOT: 31, GPT: 49, HBeAg - EIA Hepatitis B e: 1236.
I would like to know if these values indicate that inflammation is still ongoing or if there has been improvement to the point where medication is no longer necessary.
Additionally, a previous abdominal ultrasound indicated that the doctor observed small lymph nodes near the liver.
I am wondering if this is related to the condition.
Thank you for your assistance.
Xiao, 20~29 year old female. Ask Date: 2023/12/05
Dr. Chen Shidian reply Gastroenterology and Hepatology
Inflammation is improving (very effectively), long-term medication is required, do not discontinue on your own, and regular follow-up is necessary.
Reply Date: 2023/12/05
More Info
Based on your blood test results and the context provided, it appears that you are experiencing a significant improvement in your liver function and hepatitis B status. Let's break down the key components of your results and what they indicate.
1. Liver Enzymes (GOT and GPT): Your initial results on August 29 showed elevated levels of GOT (75 U/L) and GPT (187 U/L), which are indicative of liver inflammation or damage. However, your follow-up results on December 1 showed a marked decrease in these levels, with GOT at 31 U/L and GPT at 49 U/L. This reduction suggests that your liver is healing and that the inflammation is subsiding. Normal ranges for these enzymes are typically around 10-40 U/L for GOT and 7-56 U/L for GPT, so while you are still above the normal range, the trend is positive.
2. HBeAg Levels: The HBeAg (Hepatitis B e Antigen) levels have decreased from 1380 to 1236. While these values are still elevated, the decrease indicates that the viral replication may be slowing down. HBeAg positivity often correlates with active viral replication, and a decrease in its levels can suggest that the virus is becoming less active. However, it is essential to continue monitoring these levels, as they can fluctuate.
3. Treatment Considerations: You mentioned that you have been on antiviral medication (likely entecavir or a similar drug) for about three months. The improvement in your liver enzymes and the decrease in HBeAg levels are encouraging signs that the medication is working. It is crucial to continue your prescribed treatment and not to discontinue it without consulting your healthcare provider. Stopping antiviral therapy prematurely can lead to a rebound in viral activity and potentially worsen your condition.
4. Lymph Nodes Near the Liver: Regarding the small lymph nodes near your liver observed during the abdominal ultrasound, it is essential to discuss this with your doctor. Lymph nodes can become enlarged due to various reasons, including infections, inflammation, or other underlying conditions. In the context of hepatitis B, it is not uncommon for lymph nodes to react to the viral infection. However, your healthcare provider may want to monitor these lymph nodes to ensure they are not indicative of a more serious issue.
5. Next Steps: Given your current results, it is advisable to continue regular follow-ups with your healthcare provider. They may recommend further blood tests to monitor your liver function, viral load, and HBeAg levels. Additionally, they may suggest imaging studies if there are concerns about the lymph nodes or if your symptoms persist.
In summary, your recent blood test results indicate an improvement in liver function and a potential decrease in viral activity. It is crucial to maintain your treatment regimen and continue monitoring your condition with your healthcare provider. If you have any concerns about your symptoms or test results, do not hesitate to reach out to your doctor for further evaluation and guidance. Your health and well-being are paramount, and staying informed and proactive in your care is essential.
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