Mycoplasma Testing & Treatment
Hello Doctor, on September 15, I underwent a sexually transmitted infection screening at the hospital, where my blood test showed positive for Chlamydia IgM (5.0) and negative for IgG.
I took D green antibiotics for five weeks and did not engage in sexual activity during this period.
On November 17, I tested negative for Chlamydia IgA at a medical laboratory.
After that, I engaged in sexual activity (the partner also tested negative).
On December 5, I returned to the hospital for a follow-up blood test, which still showed positive IgM (2.7) and negative IgG.
The doctor suggested continuing antibiotics for another four weeks, believing my immune system is weak.
However, the next day, I had a urine PCR test at the medical laboratory, and the result was negative.
I am unclear about whether I have fully recovered (I had no symptoms during this period, only a Candida infection during treatment, which improved with suppository treatment).
Can I engage in sexual activity? Is it advisable to continue the antibiotics for another four weeks?
H, 20~29 year old female. Ask Date: 2023/12/09
Dr. Du Shixi reply Urology
Hello: It is necessary to seek medical examination when asymptomatic to confirm whether there is an infection, and practicing safe behaviors is essential.
Wishing you good health.
Reply Date: 2023/12/09
More Info
Understanding Chlamydia Testing and Treatment: Your Results and Next Steps
Thank you for sharing your detailed medical history regarding your chlamydia testing and treatment. It’s understandable to feel confused about your results and what they mean for your health and future sexual activity. Let’s break down your situation step by step.
1. Understanding Your Test Results:
- IgM and IgG Antibodies: The presence of IgM antibodies typically indicates a recent infection, while IgG antibodies suggest a past infection. In your case, the positive IgM result (5.0) and negative IgG result indicate that you may have had a recent chlamydia infection, which aligns with your initial diagnosis.
- Subsequent Testing: Your follow-up tests showed a decrease in IgM (2.7) and a negative IgA result, which is a good sign. The negative IgA suggests that there is no active infection at that moment. However, the persistence of IgM can sometimes occur even after treatment, as the immune response can take time to normalize.
2. PCR Testing:
- The PCR (Polymerase Chain Reaction) test you underwent is a highly sensitive method for detecting the presence of chlamydia DNA in urine. A negative PCR result is very reassuring and suggests that there is no active chlamydia infection at the time of testing. This is a crucial piece of information, as it indicates that the antibiotic treatment was effective in clearing the infection.
3. Treatment Continuation:
- Your doctor’s recommendation to continue antibiotics for an additional four weeks may be based on the persistence of your IgM levels. While it’s common for IgM to remain positive for some time after the infection has cleared, your doctor may be taking a cautious approach to ensure that any residual infection is fully treated. If you are asymptomatic and your PCR test is negative, it may be reasonable to discuss with your doctor whether continuing antibiotics is necessary.
4. Resuming Sexual Activity:
- Given that your PCR test is negative and you have been asymptomatic, it is generally considered safe to resume sexual activity. However, it’s essential to ensure that your partner has also been tested and treated if necessary to prevent reinfection. Open communication with your partner about testing and treatment is crucial for both of your health.
5. Next Steps:
- If you have concerns about the necessity of continuing antibiotics, it would be beneficial to have a conversation with your healthcare provider. They can provide personalized advice based on your specific situation and may consider additional testing if needed.
- Additionally, consider regular follow-up testing, especially if you have new partners or if you experience any symptoms in the future.
In summary, your negative PCR result is a strong indicator that you are no longer infected with chlamydia. While the presence of IgM antibodies can be concerning, it does not necessarily mean that you have an active infection. Always consult with your healthcare provider for tailored advice and to address any lingering concerns you may have. Remember, maintaining open communication with your sexual partners and practicing safe sex are vital components of sexual health.
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