Mild Dysplasia in Cervical Biopsies and Hormonal Treatment - Obstetrics and Gynecology

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Cervical cancer issues


I would like to ask why the doctor said that my cervical biopsy showed mild dysplasia and that taking hormones would help improve it.
Is there no need for other treatments?

y, 30~39 year old female. Ask Date: 2023/12/10

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, you may consider undergoing a cone biopsy.
You can consult your obstetrician-gynecologist.
Wishing you good health.

Reply Date: 2023/12/10

More Info


Mild dysplasia, also known as CIN 1 (Cervical Intraepithelial Neoplasia grade 1), is a condition where there are slight changes in the cells on the surface of the cervix. These changes are typically considered low-grade and often resolve on their own without any treatment. The presence of mild dysplasia indicates that the cells are abnormal but not cancerous. In many cases, especially in younger women, the body’s immune system can clear these abnormal cells naturally over time.

When your doctor suggests hormonal treatment, it is likely based on the understanding that hormonal balance can influence cervical cell health. Hormones, particularly estrogen and progesterone, play a significant role in the regulation of the menstrual cycle and the health of the cervical tissue. Some studies suggest that hormonal treatments may help in restoring the normal function of cervical cells, potentially aiding in the regression of mild dysplastic changes. This approach is particularly relevant if there are underlying hormonal imbalances that could be contributing to the abnormal cell changes.

It’s important to note that while hormonal treatment can be beneficial, it is not always necessary for mild dysplasia. The standard approach for CIN 1 is often active surveillance, which means regular monitoring through Pap smears and HPV testing rather than immediate intervention. Most women with mild dysplasia will not require surgical treatment, as the condition is often self-limiting.

However, your doctor may recommend hormonal treatment for several reasons:
1. Hormonal Imbalance: If there is evidence of hormonal imbalance, treating it may help improve cervical health and reduce the risk of progression to more severe dysplasia.

2. Symptom Management: Hormonal treatments can also help manage symptoms related to menstrual irregularities or other hormonal issues, which may indirectly support cervical health.

3. Personalized Care: Each case is unique, and your doctor may have specific reasons based on your medical history, age, and overall health that make hormonal treatment a suitable option for you.

Regarding the need for other treatments, if your mild dysplasia is confirmed and monitored regularly, additional interventions such as surgical procedures (e.g., LEEP or conization) are typically reserved for cases of moderate to severe dysplasia (CIN 2 or CIN 3) or if there are other concerning findings. Since your diagnosis is mild, the focus will likely be on monitoring and possibly hormonal treatment rather than invasive procedures.

In conclusion, while mild dysplasia is a condition that warrants attention, it is often manageable with careful monitoring and, in some cases, hormonal treatment. Regular follow-ups with your healthcare provider are essential to ensure that any changes in your cervical health are promptly addressed. Always feel free to discuss any concerns or questions you have with your doctor, as they can provide personalized advice based on your specific situation.

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