Effectiveness of Commercial Disinfectants Against Helicobacter Pylori - Gastroenterology and Hepatology

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The antibacterial efficacy of commercially available disinfectants?


Hello doctor, I apologize for bothering you again.
I would like to ask one more question: Is it effective to spray commercially available disinfectants, such as Noroclean spray (400ml, hypochlorous acid solution, made in Japan), on surfaces to kill Helicobacter pylori present on those surfaces?

Ke Ke, 10~19 year old female. Ask Date: 2024/01/10

Dr. Chen Shidian reply Gastroenterology and Hepatology


I'm sorry, I don't understand the relevant information.

Reply Date: 2024/01/10

More Info


When it comes to the effectiveness of commercial disinfectants against Helicobacter pylori (H. pylori), it's important to understand both the nature of the bacteria and the properties of the disinfectants being used. H. pylori is a gram-negative bacterium that primarily resides in the gastric mucosa and is known to be a major cause of peptic ulcers and gastric cancer. Therefore, effective disinfection is crucial in preventing its transmission and infection.

Commercial disinfectants, such as those containing hypochlorous acid (like the Noroclean spray you mentioned), are generally effective against a wide range of pathogens, including bacteria, viruses, and fungi. Hypochlorous acid is known for its antimicrobial properties, and studies have shown that it can effectively kill various bacteria, including H. pylori, on surfaces. However, the effectiveness can depend on several factors, including the concentration of the disinfectant, the contact time, and the nature of the surface being disinfected.

For instance, when using a disinfectant like hypochlorous acid, it is essential to follow the manufacturer's instructions regarding dilution and application. Typically, the disinfectant should be sprayed onto the surface and allowed to sit for a specific period to ensure that it effectively kills the bacteria. This contact time is crucial because if the disinfectant is wiped off too quickly, it may not have sufficient time to act on the bacteria.

Moreover, while disinfectants can kill H. pylori on surfaces, it is important to note that the primary mode of transmission of H. pylori is through oral-oral or fecal-oral routes. This means that while disinfecting surfaces can help reduce the risk of transmission, it is equally important to maintain good hygiene practices, such as washing hands thoroughly, especially before meals and after using the restroom.

In terms of practical application, if you are using a disinfectant spray like Noroclean, it is advisable to apply it in a well-ventilated area and to allow it to dry completely on the surface. After application, it is also a good practice to rinse the surface with clean water, especially if it will come into contact with food or utensils, to avoid any potential irritation from the disinfectant.

In conclusion, commercial disinfectants containing hypochlorous acid can be effective against H. pylori on surfaces, provided they are used correctly. However, it is essential to combine surface disinfection with proper hygiene practices to effectively prevent H. pylori infection. If you have any further questions or concerns about H. pylori or the use of disinfectants, feel free to ask.

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