Can Disinfectant Spray Kill Helicobacter Pylori on Surfaces? - Family Medicine

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A cleanliness issue?


Hello doctor, I would like to ask if commercially available disinfectant (hypochlorous acid solution) can kill Helicobacter pylori on surfaces (such as a mouse) when sprayed on them?

Ke Ke, 10~19 year old female. Ask Date: 2024/01/10

Dr. Lin Zhebin reply Family Medicine


Hello: Hypochlorous acid water should have a bactericidal effect against Helicobacter pylori, but it can be irritating to the skin.
Therefore, it is more suitable for use in home environments and for cleaning utensils.
It is recommended to use it in a well-ventilated area, allowing it to sit for a few minutes after wiping before rinsing with clean water.

Reply Date: 2024/01/10

More Info


When it comes to disinfecting surfaces that may harbor Helicobacter pylori (H. pylori), it's essential to understand the characteristics of this bacterium and the effectiveness of various disinfectants. H. pylori is a gram-negative bacterium primarily known for its role in causing gastric ulcers and chronic gastritis. It is typically transmitted via the oral-fecal route, and while it can survive in the acidic environment of the stomach, it is not particularly resilient on surfaces.

Disinfectant sprays, particularly those containing sodium hypochlorite (commonly known as bleach), can be effective against a wide range of pathogens, including H. pylori. Sodium hypochlorite works by denaturing proteins and disrupting cellular functions, leading to the death of the bacteria. When using disinfectants, it is crucial to follow the manufacturer's instructions regarding dilution, contact time, and surface compatibility.

For effective disinfection of surfaces like a computer mouse, here are some steps to consider:
1. Preparation: Before applying any disinfectant, ensure that the surface is clean. Remove any visible dirt or organic matter, as these can shield bacteria from the disinfectant.

2. Application: Apply the disinfectant spray evenly over the surface. If using a sodium hypochlorite solution, ensure it is diluted appropriately (typically around 1000-5000 ppm for general disinfection).

3. Contact Time: Allow the disinfectant to remain on the surface for the recommended contact time. This is crucial for ensuring that the disinfectant has enough time to kill the bacteria effectively. The contact time can vary depending on the product, but it is often around 5-10 minutes.

4. Rinse (if necessary): Some disinfectants may require rinsing after application, especially if they are used on surfaces that come into contact with food or skin. Check the product label for specific instructions.

5. Drying: Allow the surface to air dry completely after disinfection. This helps ensure that any remaining bacteria are killed and that the surface is safe to use.

While alcohol-based disinfectants (like 75% ethanol) can also kill many types of bacteria, their effectiveness against H. pylori specifically may not be as robust as that of sodium hypochlorite. Alcohol can evaporate quickly, which may limit its contact time with the bacteria on surfaces. Therefore, while it can reduce the bacterial load, it may not guarantee complete eradication.

In summary, using a disinfectant spray containing sodium hypochlorite is a viable method for killing H. pylori on surfaces. However, it is essential to follow proper cleaning and disinfection protocols to ensure effectiveness. Additionally, maintaining good hygiene practices, such as regular handwashing and avoiding sharing personal items, can further reduce the risk of H. pylori transmission. If there are concerns about H. pylori infection or related health issues, consulting a healthcare professional is advisable for appropriate testing and treatment options.

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