Myocardial Perfusion Imaging in Aortic Dissection Patients - Cardiology

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Myocardial perfusion imaging


Hello Dr.
Wu, I have a history of type B aortic dissection and have had an aortic stent placed for four and a half years.
Over the years, I have occasionally experienced chest tightness and pain, which prompted me to undergo a myocardial perfusion study.
The report is as follows:
[Clinical Information] Palpitations and left chest pain were noted occasionally; history of cardiovascular disease, type B aortic dissection with uncontrolled pain and hypertension status post TEVAR on September 13, 2018.

[Procedure] The myocardial perfusion imaging was performed after intravenous injection of dipyridamole and Tl-201 3 mCi.

[Finding] The stress imaging shows mildly decreased perfusion in a small area of the inferolateral wall, likely with attenuation artifact in the inferior region.
Extracardiac radioactivity adjacent to the inferior wall is attributed to abdominal activity.
The rest imaging shows complete redistribution.

[Impression]
1.
Mild myocardial ischemia in a small area of the inferolateral wall.

2.
The functional analysis reveals adequate left ventricular (LV) systolic function without regional wall motion abnormality.

3.
Mild coronary artery disease (CAD) involving the territory of the left circumflex artery (LCx) is suspected.

4.
All regions of the LV myocardium are viable.

5.
Wall motion study: post-stress: normokinesis; rest: normokinesis.

6.
Estimated LV ejection fraction: post-stress: 75%; rest: 74%.

I would like to ask Dr.
Wu if this degree of findings necessitates a cardiac catheterization or treatment.
Thank you for your response.

Jiang Xiansheng, 50~59 year old female. Ask Date: 2024/01/24

Dr. Wu Xueming reply Cardiology


The myocardial perfusion scan shows mild myocardial hypoxia.
If symptoms persist despite pharmacological management, coronary angiography may be considered.

Reply Date: 2024/01/24

More Info


Understanding myocardial perfusion imaging (MPI) in patients with a history of aortic dissection, particularly in your case with a B-type aortic dissection and a stent placement, is crucial for assessing cardiac health and determining the need for further intervention, such as coronary angiography.

Your MPI report indicates that there is mild myocardial ischemia in a small area of the inferolateral wall, which is a significant finding. The presence of ischemia suggests that there may be inadequate blood flow to that region of the heart muscle, potentially due to underlying coronary artery disease (CAD). The report also notes that there is complete redistribution in the resting images, which is a positive sign indicating that the affected area is still viable and can recover blood flow when not under stress.

The findings of adequate left ventricular (LV) systolic function, with an estimated ejection fraction of 75% during stress and 74% at rest, are reassuring. This suggests that your heart is still functioning well overall, despite the mild ischemia observed. The absence of regional wall motion abnormalities further supports the notion that your heart's pumping ability is intact.

Given your history of aortic dissection and the current findings, the decision to proceed with coronary angiography should be made in conjunction with your cardiologist. Here are some considerations that may influence this decision:
1. Symptomatology: If you are experiencing recurrent chest pain or discomfort, this could warrant further investigation. The presence of symptoms, especially in the context of a known history of aortic dissection, raises the concern for potential complications or concurrent coronary artery disease.

2. Risk Factors: Your report indicates mild CAD involving the territory of the left circumflex artery (LCx). This, combined with your history of hypertension and aortic dissection, may increase your risk for significant coronary events.
3. Non-invasive Testing Limitations: While MPI is a valuable tool for assessing myocardial perfusion, it is not definitive. If there is a high suspicion of significant CAD based on your symptoms and risk factors, coronary angiography may provide clearer insights into the state of your coronary arteries.

4. Management of Aortic Dissection: In patients with a history of aortic dissection, careful monitoring of cardiovascular health is essential. The presence of CAD can complicate the management of aortic dissection, and understanding the full picture of your cardiovascular status is vital for optimal treatment planning.

5. Consultation with Specialists: It is essential to have a thorough discussion with your cardiologist, who can evaluate the MPI findings in the context of your overall health, symptoms, and history. They may recommend coronary angiography if they believe that the potential benefits of further investigation outweigh the risks.

In conclusion, while your MPI results indicate mild ischemia, the decision to proceed with coronary angiography should be based on a comprehensive evaluation of your symptoms, risk factors, and the potential implications of your aortic dissection. Engaging in a detailed discussion with your healthcare provider will help clarify the best course of action tailored to your specific situation.

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