Blood Pressure Medication Changes: Risks and Concerns - Cardiology

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Issues with Hypertension Medications


Hello, my mother has been taking half a tablet of Amlodipine at 6 PM for hypertension for over three years.
Her usual morning blood pressure is around 120/59 with a heart rate of about 108.
Recently, after breakfast, her blood pressure has dropped to 103/55 with a heart rate of 102, or even 96/48 with a heart rate of 102, accompanied by dizziness, requiring her to lie down to feel better.
At 5 PM, her blood pressure was measured at 136/60 with a heart rate of 96.
During her follow-up appointment, she mentioned her symptoms to the doctor, who said her blood pressure looked fine and switched her medication to one tablet of Lisinopril.
I would like to ask if taking medication for so many years can suddenly cause low blood pressure, and whether Lisinopril is stronger than Amlodipine.
I am very concerned that switching to a stronger medication might cause her blood pressure to drop to the point of shock.

Miss Zhu, 30~39 year old female. Ask Date: 2024/01/25

Dr. Chen Jili reply Cardiology


I recommend that you: 1.
Discuss the above situation further with your attending physician.
2.
Consider consulting a cardiologist at a major hospital.
Wishing you good health.
Thank you!

Reply Date: 2024/01/25

More Info


Hello! Thank you for your question regarding blood pressure medication changes and the associated risks and concerns. It sounds like your mother has been managing her hypertension with a medication called "舒脈優" (which I assume is a brand name for a specific antihypertensive medication) for over three years. Recently, however, she has experienced episodes of low blood pressure, particularly in the morning after breakfast, which has led to symptoms like dizziness and the need to lie down.

Firstly, it's important to understand that blood pressure can fluctuate throughout the day due to various factors, including hydration status, physical activity, stress levels, and dietary intake. The readings you provided indicate that your mother's blood pressure can drop significantly in the morning, which may be concerning, especially when accompanied by symptoms like dizziness.

The change in medication to "優雅錠" (another antihypertensive) raises valid concerns. It's not uncommon for doctors to adjust medications based on a patient's current health status and response to treatment. The new medication may have a different mechanism of action or potency compared to "舒脈優." While "優雅錠" may be more effective for some patients, it could also lead to lower blood pressure readings, especially if the dosage is higher or if it works more aggressively to lower blood pressure.

Regarding the potential for low blood pressure after long-term use of a medication, it is indeed possible for patients to experience changes in their blood pressure response over time. Factors such as changes in body weight, diet, physical activity, and even the progression of underlying health conditions can influence how the body responds to medications. Additionally, if your mother has been on the same medication for an extended period, her body may have adapted to it, and a sudden change in medication could lead to unexpected effects, including hypotension (low blood pressure).

It's crucial to monitor her blood pressure closely after the medication change. If her blood pressure readings remain low or if she continues to experience symptoms like dizziness, it would be advisable to contact her healthcare provider. They may need to adjust the dosage or consider alternative treatment options to ensure her blood pressure remains within a safe range.

In terms of the fear of experiencing severe hypotension or shock, it's essential to communicate these concerns with her doctor. They can provide reassurance and guidance on what to expect with the new medication. It's also important to educate her on recognizing signs of low blood pressure, such as dizziness, fainting, or extreme fatigue, and to know when to seek medical attention.

In summary, while changes in blood pressure medication can lead to fluctuations in blood pressure, careful monitoring and communication with healthcare providers can help manage these risks effectively. Encourage your mother to keep a log of her blood pressure readings and any symptoms she experiences, as this information can be invaluable for her healthcare team in making informed decisions about her treatment plan.

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