Lymph Nodes: Symptoms and Concerns in Oncology - Oncology

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Cervical lymph nodes


Last March, I discovered a swollen lymph node in my neck.
Since then, I have noticed several more swollen lymph nodes in my neck.
I have been continuously monitoring the situation.
Initially, an ultrasound was performed, followed by a CT scan of my neck, and the doctors have determined that the lymph nodes are benign, and they all seem to be less than one centimeter in size, although their quantity has increased.
Recently, over the past two weeks, I have come down with a cold for an unknown reason.
I initially had a fever of 39 degrees Celsius, but after taking antipyretics, it has decreased.
However, I have noticed that when I wake up, my clothes are slightly damp, and I feel like I am sweating, although my body is dry.
I have been experiencing low-grade fevers in the afternoons and a slight cough, but it seems to be improving compared to the initial onset.
I would like to ask the doctor: 1.
If the initially swollen lymph node was lymphoma, is it possible for symptoms like fever and night sweats to appear only now? 2.
Can lymphoma present with lymph nodes that are less than one centimeter in size?

Mr. Wang, 20~29 year old female. Ask Date: 2024/01/25

Dr. Chen Sirong reply Oncology


1.
Is it possible for symptoms like fever and night sweats to appear now if the swollen lymph node was initially lymphoma? A: It is possible, but just a possibility.
However, if the lymphoma is present, that lymph node would likely continue to grow.
If it hasn't increased in size, it is less likely to be lymphoma.
2.
Can lymphoma be smaller than one centimeter? A: Of course, it starts from a single malignant mutated cell becoming cancerous, which is not visible to the naked eye or palpable, at sizes like 0.5 cm, 1 cm, and gradually growing to 2 cm.
However, if it is malignant, it typically will not remain less than 1 cm indefinitely.
Wishing you a happy New Year, Taoyuan Hospital, Chen Si-Rong.

Reply Date: 2024/01/25

More Info


Understanding lymph nodes and their implications in oncology is crucial, especially when there are symptoms like swelling, fever, and night sweats. Based on the information provided, let’s address your concerns regarding the lymph nodes and the potential for lymphoma.

1. Could the initial swollen lymph node indicate lymphoma, with symptoms like fever and night sweats appearing later?
Lymphoma, a type of cancer that originates in the lymphatic system, can indeed present with swollen lymph nodes. However, the symptoms you are experiencing—fever, night sweats, and cough—are more commonly associated with systemic illnesses or infections rather than lymphoma, especially if the lymph nodes have been assessed multiple times and deemed benign. In lymphoma, systemic symptoms such as fever, night sweats, and unexplained weight loss (often referred to as "B symptoms") typically occur when the disease is more advanced. If the initial swollen lymph node was indeed lymphoma, it is plausible that these systemic symptoms could develop later; however, it is essential to consider other factors, such as infections or inflammatory conditions, which can also cause similar symptoms.

2. Can lymphoma present with lymph nodes smaller than one centimeter?
Yes, lymphomas can present with lymph nodes that are less than one centimeter in size. In fact, many benign conditions, including infections and reactive lymphadenopathy, can cause lymph nodes to swell, and these nodes can vary in size. Lymph nodes that are less than one centimeter are often considered normal, especially in the context of a reactive process. However, the size of lymph nodes alone is not a definitive indicator of malignancy. The characteristics of the lymph nodes, such as their shape, consistency, and whether they are tender or fixed, are also important factors in determining their nature.

Given your recent symptoms of fever and night sweats, it is advisable to consult with your healthcare provider. They may recommend further investigations, such as blood tests or imaging studies, to rule out any underlying infections or other conditions that could explain your symptoms. It is also essential to keep monitoring the lymph nodes and report any changes to your doctor.

In summary, while the presence of swollen lymph nodes can be concerning, especially with accompanying symptoms, it is crucial to interpret these findings in the context of a comprehensive clinical evaluation. Regular follow-ups and open communication with your healthcare provider are key to managing your health and addressing any concerns about potential malignancies like lymphoma.

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