EPS Symptoms After Gastroenteritis Treatment: A Neurology Perspective - Neurology

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Symptom Analysis


Last week, after taking antiemetics for gastroenteritis, I experienced extrapyramidal symptoms (EPS).
It started with my teeth chattering, followed by sudden jaw deviation.
I immediately went to the emergency room for an injection, which corrected the jaw misalignment.
However, the next day, the chattering of my teeth persisted without improvement.
Since January 26, my appetite has been poor, and I feel my metabolism has also declined a bit.
I've been very worried about having a serious illness, so I visited a small clinic (neurology) yesterday.
They only performed an EEG and prescribed medication for me to take at home.
My medications include one tablet of biperiden HCl after breakfast and dinner, and one tablet of fludiazepam before bedtime.
Last night, after taking a tablet, my muscles began to twitch involuntarily and frequently.
Are these still symptoms of EPS? What insights does the doctor have regarding my situation? P.S.
I smoke and was anxious until after 4 AM before falling asleep.

Chen Daxuesheng, 10~19 year old female. Ask Date: 2024/02/04

Dr. Jiang Junyi reply Neurology


Hello Mr.
Chen: You mentioned, "Last night before bed, I took a muscle relaxant and my muscles started twitching involuntarily." Generally speaking, symptoms of extrapyramidal syndrome (EPS) caused by medication typically improve within three days after discontinuation.
Your symptoms may need to be evaluated for other factors, such as metabolic disorders like hyperthyroidism or electrolyte imbalances.
Foods that stimulate the nervous system, such as caffeine, may also exacerbate muscle twitching while awake.
Neurologists specializing in neuromuscular diseases are more familiar with these types of conditions, and I recommend consulting with such a specialist.
Thank you for your question, and feel free to discuss further.
Wishing you good health and peace.
Dr.
Jiang Junyi, Taoyuan Medical Center, cares about you.

Reply Date: 2024/02/04

More Info


Understanding Extrapyramidal Symptoms (EPS) after gastroenteritis treatment requires a multifaceted approach, particularly from a neurology perspective. Extrapyramidal symptoms are drug-induced movement disorders that can occur as a side effect of certain medications, particularly antipsychotics and antiemetics. In your case, it seems that the antiemetic medication you took for gastroenteritis may have triggered these symptoms.

Initially, you experienced tremors in your teeth and a sudden deviation of your jaw, which are indicative of EPS. These symptoms can arise due to the disruption of dopamine pathways in the brain, particularly in the basal ganglia, which is responsible for coordinating movement. The fact that you sought emergency care and received treatment that alleviated the jaw deviation suggests that the acute symptoms were effectively managed, but the persistence of the tremors indicates that the underlying issue may not have been fully resolved.

The medication you were prescribed, Biperiden HCl, is an anticholinergic agent commonly used to treat EPS. It works by restoring the balance between dopamine and acetylcholine in the brain, which can help alleviate the symptoms you are experiencing. Fludiazepam, a benzodiazepine, is often prescribed for anxiety and can help with muscle relaxation and sleep, but it may not directly address the EPS symptoms.

Your ongoing symptoms, including the involuntary muscle movements and poor appetite, could indeed be related to the EPS. It's essential to monitor these symptoms closely. If they persist or worsen, it may be necessary to revisit your neurologist or primary care physician for a reevaluation of your treatment plan. They may consider adjusting your medications or exploring alternative therapies to manage your symptoms more effectively.

Additionally, your mention of anxiety and sleep disturbances is significant. Anxiety can exacerbate physical symptoms and may contribute to the perception of worsening health. It's crucial to address both the neurological symptoms and the psychological aspects of your condition. Engaging in relaxation techniques, cognitive behavioral therapy, or other forms of psychological support may help alleviate some of the anxiety you are experiencing.

Regarding your concerns about serious underlying diseases, it's understandable to feel anxious after experiencing such distressing symptoms. However, it’s important to focus on the management of your current symptoms and to maintain open communication with your healthcare providers. Regular follow-ups and possibly further diagnostic tests may be warranted to ensure that no other conditions are contributing to your symptoms.

In summary, your EPS symptoms following gastroenteritis treatment are likely related to the medications you received. The prescribed Biperiden HCl should help manage these symptoms, while Fludiazepam can assist with anxiety and sleep. It's crucial to monitor your symptoms closely and maintain communication with your healthcare providers to ensure effective management and to address any concerns about your overall health. If symptoms persist or worsen, further evaluation and adjustment of your treatment plan may be necessary.

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