Lymph Node Swelling: When to Seek Further Evaluation - Otolaryngology

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Regarding lymphadenopathy?


During the Lunar New Year this year, I noticed a small round lump on the left side of my neck that is not painful, measuring approximately 0.7 to 0.8 centimeters in diameter.
I consulted an ENT specialist who mentioned that it is not a serious condition (such as lymphoma) and suggested that it might be caused by an infection.
They prescribed antibiotics, but after three weeks, the swelling has not decreased, although it hasn't increased in size either.
Is this considered normal? If a biopsy is needed, would it require surgery on my neck?

xiao, 20~29 year old female. Ask Date: 2004/02/15

Dr. Cai Zhenggu reply Otolaryngology


Hello, based on your description, it could be cervical lymphadenitis.
After medication, it may remain unchanged.
If a biopsy is needed, surgery will be required on the neck.

Reply Date: 2004/02/15

More Info


When it comes to swollen lymph nodes, particularly in the neck, it’s important to understand the potential causes and when further evaluation is necessary. Lymph nodes can swell due to a variety of reasons, including infections, inflammatory conditions, or malignancies. In your case, you have noticed a small, painless lump on the left side of your neck, measuring approximately 0.7 to 0.8 cm, which has not changed in size after three weeks of antibiotic treatment prescribed by an ENT specialist.

The fact that your lymph node is not painful and has not increased in size is somewhat reassuring, as painful and rapidly enlarging lymph nodes are often more concerning. Infections, such as viral or bacterial infections, can cause lymph nodes to swell, and they often resolve on their own as the infection clears. However, if a lymph node remains swollen for an extended period, as in your case, it may warrant further investigation.

The recommendation from your ENT doctor that this is likely not a serious condition is a positive sign, but it’s essential to monitor the situation. If the lymph node remains unchanged or continues to persist beyond a few weeks, further evaluation may be necessary. This could include imaging studies, such as an ultrasound or CT scan, to assess the characteristics of the lymph node and surrounding tissues.

In terms of whether a biopsy is needed, this typically depends on the findings from imaging studies and the clinical context. If the lymph node appears suspicious based on imaging or if there are other concerning symptoms (such as unexplained weight loss, night sweats, or persistent fever), a biopsy may be warranted. A biopsy can be performed in several ways, including:
1. Fine Needle Aspiration (FNA): This is a minimally invasive procedure where a thin needle is inserted into the lymph node to extract a small sample of tissue. It can often be done in an outpatient setting and does not require a large incision.

2. Core Needle Biopsy: This involves using a larger needle to obtain a bigger tissue sample and may provide more information than an FNA.

3. Excisional Biopsy: If the lymph node is larger or if the previous methods are inconclusive, a surgical excisional biopsy may be performed, where the entire lymph node is removed for examination.

In your case, if the lymph node continues to persist without change, it may be advisable to discuss with your healthcare provider the possibility of imaging studies to evaluate the lymph node further. If imaging suggests any abnormalities or if there are other clinical concerns, a biopsy may be recommended.

In summary, while your lymph node's characteristics are somewhat reassuring, ongoing monitoring is essential. If it remains unchanged or if you develop new symptoms, further evaluation, including imaging and possibly a biopsy, may be necessary to rule out any serious underlying conditions. Always consult with your healthcare provider for personalized advice based on your specific situation.

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