Diarrhea and Weight Loss: A Gastrointestinal Concern - Gastroenterology and Hepatology

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Diarrhea and weight loss?


Hello doctor, the following content is a question for my mother, and I hope you can help answer it.
My mother has been experiencing diarrhea for the past two months.
The common factor is that she almost always starts having severe abdominal pain around noon on weekdays, followed by frequent trips to the restroom.
Because of this, her weight has started to decrease.
However, on weekends when she is at home, she doesn't seem to have the same diarrhea issue around noon.
(My mother has tried taking anti-diarrheal medication, which stops the diarrhea temporarily, but it resumes when she doesn't take it.) She also experiences loud bowel sounds.
She visited an internal medicine clinic, and the doctor prescribed medication, which has provided slight improvement (she has been taking the medication for about two to three days), but she is still experiencing daily diarrhea.
The feeling of bloating has become less intense, and the frequency of restroom visits has decreased, but she continues to have diarrhea every day.
After researching a lot online, she is becoming increasingly worried, especially since the internet suggests that weight loss can be a sign of serious illness...

Qing, 50~59 year old female. Ask Date: 2024/03/01

Dr. Chen Shidian reply Gastroenterology and Hepatology


Fecal occult blood testing can be performed, and if positive, a colonoscopy should be conducted.
Additionally, continuous monitoring of weight changes is recommended.

Reply Date: 2024/03/01

More Info


Diarrhea and weight loss can be concerning symptoms, especially when they persist over a period of time. In your mother's case, the fact that she experiences severe abdominal pain and diarrhea primarily during weekdays suggests a possible connection to her daily routine, diet, or stress levels. It is important to consider various factors that could be contributing to her symptoms.

Firstly, the timing of her symptoms—occurring mostly during weekdays—may indicate that stress or anxiety related to work or daily responsibilities could be playing a role. Stress can significantly affect gastrointestinal function, leading to conditions such as irritable bowel syndrome (IBS), which is characterized by abdominal pain and altered bowel habits. In IBS, symptoms can often be triggered by stress, certain foods, or changes in routine.
Additionally, the fact that her symptoms improve during weekends when she is at home suggests that her environment or dietary choices during the week may be influencing her gastrointestinal health. It would be beneficial to keep a food diary to identify any potential food triggers that could be exacerbating her symptoms. Common triggers include dairy products, gluten, spicy foods, and high-fat meals.
The use of anti-diarrheal medications may provide temporary relief, but they do not address the underlying cause of the diarrhea. Since her symptoms have shown some improvement with medication, it is a positive sign, but the persistence of diarrhea indicates that further investigation is warranted.
Weight loss is another significant concern. Unintentional weight loss can be a red flag for various underlying health issues, including malabsorption syndromes, chronic infections, inflammatory bowel disease (IBD), or even malignancies. Given that your mother has experienced a notable decrease in weight alongside her gastrointestinal symptoms, it is essential to conduct a thorough evaluation. This may include blood tests to check for anemia, electrolyte imbalances, and markers of inflammation, as well as stool tests to rule out infections or malabsorption issues.

It is also important to consider the possibility of chronic conditions such as celiac disease or Crohn's disease, which can lead to diarrhea and weight loss. If her symptoms persist despite treatment, further diagnostic procedures such as endoscopy or colonoscopy may be necessary to visualize the gastrointestinal tract and obtain biopsies if needed.

In conclusion, while your mother's symptoms of diarrhea and weight loss are concerning, they can often be managed effectively with the right approach. It is crucial to work closely with her healthcare provider to monitor her symptoms, adjust her treatment plan as needed, and conduct any necessary tests to rule out serious conditions. Encouraging her to maintain a balanced diet, manage stress, and stay hydrated will also be beneficial in her recovery. If her symptoms do not improve or worsen, seeking a gastroenterologist's opinion may provide more specialized care and insight into her condition.

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