Gonorrhea Test Results: Urine Negative, Vaginal Positive - Urology

Share to:

Testing issues


I am a female.
My urine test for gonorrhea was negative, but my vaginal discharge test was positive.
Is this possible? Which report should I refer to? Should I receive treatment? Is there a blood test for gonorrhea?

Xin Xin, 30~39 year old female. Ask Date: 2024/03/02

Dr. Du Shixi reply Urology


Hello: It is possible to require treatment for gonorrhea, which affects two systems: the urinary and vaginal systems.
Diagnosis is typically made based on symptoms or through smear tests or culture methods.
Wishing you good health.

Reply Date: 2024/03/02

More Info


When it comes to understanding gonorrhea test results, it is indeed possible to have a negative urine test while having a positive vaginal swab result. This scenario can occur due to several factors related to the testing methods and the nature of the infection itself.

Gonorrhea is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae. It can infect various mucosal surfaces in the body, including the urethra, cervix, throat, and rectum. Testing for gonorrhea can be done through different methods, including urine tests and swabs from infected areas.
1. Testing Methods:
- Urine Test: This method typically involves collecting a urine sample to check for the presence of the bacteria. It is a non-invasive method and is commonly used for screening in men and women.

- Vaginal Swab: This method involves taking a sample directly from the vaginal canal, which can provide a more accurate representation of the infection in women. The bacteria may be present in the vaginal secretions even if they are not detectable in the urine.

2. Why the Discrepancy?:
- The discrepancy between a negative urine test and a positive vaginal swab can occur because the infection may be localized to the cervix or vaginal area, which may not be adequately represented in a urine sample. Additionally, the sensitivity of the tests can vary, meaning that one method may detect the infection better than the other.

3. What to Do Next:
- Given that your vaginal swab result is positive for gonorrhea, it is crucial to follow up with treatment. Gonorrhea is typically treated with antibiotics, and it is essential to complete the full course of treatment to ensure the infection is cleared.
- You should also inform any sexual partners about your diagnosis so they can get tested and treated if necessary to prevent reinfection.

4. Blood Tests for Gonorrhea:
- Gonorrhea is not typically diagnosed through blood tests. The standard testing methods are urine tests and swabs. However, in some cases, blood tests may be used to check for complications or to rule out other STIs.

5. Follow-Up Care:
- After treatment, it is advisable to have a follow-up test to ensure that the infection has been successfully treated. This is particularly important if symptoms persist or if you have had unprotected sex after treatment.

In summary, a negative urine test combined with a positive vaginal swab for gonorrhea is possible and indicates that you should proceed with treatment based on the positive result. It is essential to consult with your healthcare provider for appropriate management and to discuss any further testing or follow-up care that may be necessary. Remember, early detection and treatment are key to preventing complications associated with gonorrhea and other STIs.

Similar Q&A

Understanding Gonorrhea Testing in Women: Urine vs. Vaginal Samples

Doctors can detect gonorrhea in females, including pregnant women and asymptomatic individuals, through urine samples or vaginal secretions. It is unlikely to have a situation where urine tests positive and vaginal secretions test negative, or vice versa.


Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, both tests are acceptable. Wishing you good health.

[Read More] Understanding Gonorrhea Testing in Women: Urine vs. Vaginal Samples


Understanding Negative Gonorrhea Test Results: What They Mean

I recently went to a testing facility for a urine test to check for gonococcal DNA, and the result came back negative. Does this mean that there is no gonococcal infection in my body? For example, does this rule out the possibility of gonococcal pharyngitis? After all, the result...


Dr. Du Shixi reply Urology
Hello: General tests cannot be 100% accurate. To confirm, one should be asymptomatic, engage in safe behaviors, and have multiple negative test results. Wishing you good health.

[Read More] Understanding Negative Gonorrhea Test Results: What They Mean


Understanding Gonorrhea Testing During Pregnancy: Urine vs. Swab Results

Doctor, I had a urine test for gonorrhea using chocolate agar culture before my prenatal check-up, which came back negative at 22 weeks of pregnancy. The gonorrhea urine PCR was also negative at 32 weeks of pregnancy. I am currently waiting for the report on the gonorrheal discha...


Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, it seems that gonorrhea is not a condition for a cesarean section. Wishing you good health.

[Read More] Understanding Gonorrhea Testing During Pregnancy: Urine vs. Swab Results


Understanding Urine Bacteria Tests: Do Negative Results Mean No Infection?

Hello, doctor: I recently underwent a health check at a local health screening center, and one of the urine tests showed negative for bacteria. Does this mean that my urine does not contain Neisseria gonorrhoeae or Chlamydia trachomatis, indicating that I am not infected with gon...


Dr. Du Shixi reply Urology
Hello: It cannot be said that way; a urine test is quite simple, and the absence of bacteria is certainly a good thing. However, the testing for gonorrhea is complex. You can refer to https://www.cdc.gov.tw/File/Get/lh6TyjM85hwqWMfnOLbT8Q for specimen collection and submission de...

[Read More] Understanding Urine Bacteria Tests: Do Negative Results Mean No Infection?


Related FAQ