Pap Smear and Biopsy Results: Mild Chronic Inflammation Explained - Obstetrics and Gynecology

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Pap smear and biopsy?


Hello Dr.
Lin: I recently had a Pap smear at the hospital that showed CIN 1.
Later, the doctor performed a biopsy, and today I found the following information uploaded in my health record under SNOMED: 83000-A-M43000DX: Uterus, cervix, biopsy----mild chronic inflammation.
GROSS DESCRIPTION: The specimen submitted consists of 3 pieces of tissue measuring 0.3 x 0.2 x 0.2 cm to 0.4 x 0.3 x 0.2 cm.
All are submitted.
MICROSCOPIC DESCRIPTION: Sections show cervical tissue with mild chronic inflammation.
I looked it up and found that it indicates mild chronic inflammation of the cervix.
Does this mean I have both conditions? Thank you.

Nìmíng, 40~49 year old female. Ask Date: 2024/03/14

Dr. Lin Xinwang reply Obstetrics and Gynecology


Hello: The Pap smear is for screening purposes, with the biopsy report being the primary basis for diagnosis.
Currently, the diagnosis is chronic cervicitis; however, it is still recommended to follow up with 3 to 6 Pap smears.

Reply Date: 2024/03/14

More Info


Understanding the results of a Pap smear and biopsy can be a source of anxiety for many patients, especially when terms like "mild chronic inflammation" and "CIN 1" (Cervical Intraepithelial Neoplasia grade 1) are involved. Let's break down what these findings mean and how they relate to each other.

A Pap smear is a screening test used to detect abnormal cells in the cervix, which can indicate the presence of precancerous changes or cervical cancer. In your case, the result of CIN 1 suggests that there are mild changes in the cervical cells, which are typically associated with human papillomavirus (HPV) infection. CIN 1 is considered a low-grade lesion and often resolves on its own without treatment.
The biopsy results you received indicate "mild chronic inflammation" in the cervical tissue. Chronic inflammation in the cervix can be caused by various factors, including persistent infections (like HPV), irritation, or other underlying conditions. The presence of mild chronic inflammation does not necessarily indicate a serious problem; it often reflects the body's response to a mild irritant or infection.

To address your concern about whether you have two separate conditions: yes, you have both CIN 1 and mild chronic inflammation. However, these findings are not uncommon and can occur together. The chronic inflammation may be a response to the changes seen in CIN 1, particularly if there is an ongoing HPV infection.

It's important to note that mild chronic inflammation itself is not a disease but rather a description of the tissue's condition. It may require monitoring, but it does not usually necessitate immediate treatment unless there are other concerning symptoms or findings.

In terms of management, your healthcare provider will likely recommend a follow-up plan. This may include regular Pap smears and HPV testing to monitor the situation. In many cases, CIN 1 resolves spontaneously, and the chronic inflammation may also improve over time.
You should maintain open communication with your healthcare provider regarding any symptoms you may experience, such as unusual bleeding, pain, or discharge. They can provide guidance on lifestyle modifications, such as smoking cessation, which can help improve cervical health and reduce inflammation.

In summary, while you have both CIN 1 and mild chronic inflammation, these findings are generally manageable and often resolve without intervention. Regular follow-up and monitoring are key to ensuring your cervical health remains stable. If you have further questions or concerns, do not hesitate to reach out to your healthcare provider for personalized advice and reassurance.

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