Hashimoto's Disease: Causes, Treatment, and Dietary Tips - Otolaryngology

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Thyroid medication consultation?


Hello Dr.
Zheng, I had a blood test a few days ago, and my metabolic doctor said that I have Hashimoto's disease.
I have also researched a lot of information online, and I would like to ask:
1.
Is Hashimoto's disease essentially a chronic inflammation of the thyroid gland, or is there a more in-depth explanation?
2.
My family has normal thyroid function; what could be the possible causes of my Hashimoto's disease?
3.
A thyroid ultrasound revealed four nodules measuring 0.4 to 0.7 cm.
My attending physician prescribed 50 mcg of levothyroxine (Eltroxin) for one month.
Will taking levothyroxine help reduce the size of the nodules? Are there any dietary factors that could be related to the nodules? What can I do to reduce the size of the nodules or prevent them from growing larger?

Eason, 40~49 year old female. Ask Date: 2024/03/28

Dr. Zheng Jueyi reply Otolaryngology


1.
Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis, is an autoimmune disease caused by the immune attack of thyroid tissue by self-cells or antibodies.
2.
In addition to family history, certain environmental factors such as high iodine intake, infectious diseases, and medications may predispose susceptible individuals to develop Hashimoto's disease.
3.
Medications can be used to control the size of nodules, and it is recommended to have regular follow-up appointments with an endocrinologist for monitoring.

Reply Date: 2024/03/28

More Info


Hashimoto's disease, also known as Hashimoto's thyroiditis, is indeed a chronic autoimmune condition that primarily affects the thyroid gland. It is characterized by the immune system mistakenly attacking the thyroid, leading to inflammation and often resulting in hypothyroidism, where the thyroid does not produce enough hormones. This condition is named after Dr. Hakaru Hashimoto, who first described it in 1912.
1. Understanding Hashimoto's Disease: Hashimoto's disease is a form of chronic thyroiditis, which is an inflammation of the thyroid gland. The inflammation is caused by an autoimmune response, where the body's immune system produces antibodies that attack the thyroid tissue. This can lead to a gradual destruction of the thyroid gland, resulting in decreased hormone production. The symptoms of Hashimoto's can vary widely, but common signs include fatigue, weight gain, cold intolerance, dry skin, hair loss, and depression. In some cases, patients may also develop a goiter, which is an enlargement of the thyroid gland.

2. Causes and Risk Factors: While the exact cause of Hashimoto's disease is not fully understood, several factors may contribute to its development. Genetic predisposition plays a significant role; however, it is possible for individuals without a family history of thyroid disease to develop Hashimoto's. Environmental factors, such as exposure to certain chemicals, radiation, and viral infections, may also trigger the onset of the disease. Additionally, hormonal changes, particularly in women, can influence the development of autoimmune conditions.

3. Thyroid Nodules and Treatment: The presence of thyroid nodules, as noted in your ultrasound report, is not uncommon in individuals with Hashimoto's disease. These nodules can be benign or, in rare cases, malignant. The treatment prescribed by your physician, Levothyroxine (often referred to by the brand name Synthroid or Euthyrox), is a synthetic form of the thyroid hormone thyroxine (T4). This medication is used to normalize thyroid hormone levels in the body. While Levothyroxine primarily addresses the hormone deficiency, it may not directly reduce the size of thyroid nodules. However, maintaining normal thyroid hormone levels can help prevent further growth of the nodules.

4. Dietary Considerations: There is ongoing research into the relationship between diet and thyroid health, particularly in autoimmune thyroid conditions. While no specific diet can cure Hashimoto's disease, certain dietary practices may support thyroid function and overall health. A diet rich in whole foods, including fruits, vegetables, lean proteins, and healthy fats, is generally recommended. Some individuals find that avoiding gluten, dairy, or highly processed foods may help alleviate symptoms, although this varies from person to person. Selenium and iodine are essential nutrients for thyroid health, but it is crucial to consult with a healthcare provider before making significant dietary changes or taking supplements, as excessive iodine can exacerbate thyroid dysfunction.

5. Monitoring and Follow-Up: Regular follow-up with your healthcare provider is essential for managing Hashimoto's disease. This includes monitoring thyroid hormone levels and assessing the size and characteristics of any nodules. If there are changes in the nodules or if you experience new symptoms, further evaluation may be necessary, including possible fine-needle aspiration biopsy to rule out malignancy.

In summary, Hashimoto's disease is a chronic autoimmune condition that affects the thyroid gland, leading to inflammation and potential hypothyroidism. While the exact cause is not fully understood, genetic and environmental factors play a role. Treatment typically involves hormone replacement therapy, and while dietary changes may support overall health, they should be approached cautiously and under medical guidance. Regular monitoring is crucial for managing the condition effectively.

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