Delayed Periods After Norethisterone: Key Questions Answered - Obstetrics and Gynecology

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After taking progesterone for seven days, my menstrual period still hasn't arrived?


2.29 The last menstrual period started, and it ended on 3.6 (my menstrual cycles are usually irregular).
On 4.6, I had some friction with my boyfriend, but there was no penetration and no ejaculation.
However, there might have been some pre-ejaculate fluid that came into contact with my vulva.
My boyfriend also touched my genital area with his hand (which had not come into contact with pre-ejaculate fluid), and afterward, I wiped it off with tissue.
On 4.9, I was concerned that my menstrual period had not arrived yet, so I went to see a doctor.
An ultrasound was performed, and the doctor said that my endometrium was slightly thickened, but everything else was normal, and my menstrual period was expected to come soon.
The doctor prescribed a seven-day course of progesterone medication (Norethisterone 5mg).
I finished taking the medication on 4.16, and on 4.17, I used a pregnancy test, which showed one line.
I would like to ask the doctor: 1.
Is it possible to become pregnant from the friction on 4.6? 2.
Is the pregnancy test result on 4.17 accurate? 3.
If my menstrual period still hasn’t arrived by 4.20 and the pregnancy test still shows one line, what should I do?

Kk, 10~19 year old female. Ask Date: 2024/04/17

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, the chances of pregnancy should be low.
Your period is expected to come within a week after finishing the medication, so just wait and see.
Wishing you good health.

Reply Date: 2024/04/17

More Info


Understanding delayed periods after taking Norethisterone can be quite complex, especially when considering various factors that can influence menstrual cycles. Let's break down your concerns and questions systematically.

1. Possibility of Pregnancy from Friction: The incident on April 6, where there was friction but no penetration or ejaculation, generally poses a low risk for pregnancy. However, it's important to note that pre-ejaculate fluid (pre-cum) can contain sperm, albeit in very small amounts. If this fluid came into contact with the vaginal area, there is a theoretical risk of pregnancy, but it is significantly lower compared to direct ejaculation. Given that you have not had a regular menstrual cycle and considering the timing of your cycle, the likelihood of pregnancy from this encounter is low, especially since you have not experienced any subsequent symptoms of pregnancy.

2. Accuracy of Pregnancy Test on April 17: The pregnancy test you took on April 17 is likely accurate, especially if it was taken after your expected period date. Most home pregnancy tests are designed to detect the hormone hCG (human chorionic gonadotropin) in urine, which typically becomes detectable about a week after a missed period. Since you took the test after completing the Norethisterone regimen and it showed one line (negative), it suggests that you are not pregnant. However, if your period does not arrive soon, it may be worth repeating the test a few days later or consulting with a healthcare provider for a blood test, which can provide more definitive results.

3. What to Do if Period Does Not Arrive by April 20: If your period has not arrived by April 20 and the pregnancy test remains negative, it is advisable to consult your healthcare provider. Delayed periods can be influenced by various factors, including hormonal imbalances, stress, changes in weight, and the effects of medications like Norethisterone. Since you have already been prescribed Norethisterone to help regulate your cycle, it is essential to follow up with your doctor to discuss your ongoing symptoms and any concerns about your menstrual health.

Norethisterone is a synthetic progestogen that can be used to delay periods or manage menstrual irregularities. It works by mimicking the natural hormone progesterone, which plays a crucial role in regulating the menstrual cycle. After stopping Norethisterone, it is common for some women to experience a delay in their period as the body readjusts to its natural hormonal rhythm. This adjustment period can vary from person to person, and it may take some time for your cycle to normalize.

In summary, while the risk of pregnancy from the described encounter is low, the negative pregnancy test is reassuring. However, if your period does not arrive soon, it is crucial to seek medical advice to rule out any underlying issues and to discuss the best course of action for managing your menstrual health. Regular monitoring and open communication with your healthcare provider are key to understanding and managing your menstrual cycle effectively.

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