Recurrent Glans Inflammation in Autoimmune Conditions

Glans issues

1.
Can autoimmune system issues, such as ankylosing spondylitis, lead to recurrent inflammation of the glans? I have noticed that it occurs almost 1-2 times a month.
2.
On March 23rd, I noticed a spot, but initially, I thought I would let it heal on its own without applying medication.
After nearly a week without improvement, I applied medication for five days.
I thought it had healed, but upon stopping the medication, I found that the red spot was still there.
Two days later, I applied medication again for three days, and now the spot has become very small; it sometimes appears and sometimes disappears.
The size is approximately that of a 0.3 mm pen tip.
Could this be a scar left by glans inflammation since it does not completely disappear?
3.
It does not hurt or itch.
I would like to ask the doctor what changes I should watch for that would warrant medical treatment.
For example, if it enlarges, bleeds, or if I should just continue to observe it.

You, 30~39 year old female. Ask Date: 2024/04/21

Dr. Du Shixi reply Urology

Hello,
1.
Could issues with the immune system lead to recurrent inflammation of the glans? I have noticed that it occurs almost 1-2 times a month.
Should this still be attributed to hygiene or contact primarily?
2.
On March 23, I noticed a spot, but initially, I thought it would heal on its own, so I didn't apply any medication.
After almost a week without improvement, I applied medication for five days.
I thought it had healed, but after stopping the medication, I found that the red spot was still there.
Two days later, I applied medication again for three days, and now the spot has become very small; it sometimes appears and sometimes disappears.
The size is approximately that of a 0.3 mm pen tip.
Could this be a scar left by glans inflammation since it never completely disappears? If it is still a red spot, I would recommend seeing a doctor, and currently, keep the area dry.
3.
It does not hurt or itch.
I would like to ask the doctor what changes would warrant medical treatment? For example, if it enlarges or bleeds, or should I just observe it? If it enlarges, you definitely need to seek medical attention.
Redness is also a reason to consult a healthcare professional.
Wishing you good health.

Reply Date: 2024/04/21

More Info

Recurrent glans inflammation, particularly in the context of autoimmune conditions like ankylosing spondylitis, can indeed be a complex issue. Autoimmune diseases can lead to various systemic effects, including skin and mucosal changes, which may predispose individuals to localized inflammation, such as that occurring on the glans (the head of the penis).
1. Connection Between Autoimmune Conditions and Glans Inflammation: Autoimmune disorders can affect the immune system's ability to regulate inflammation properly. In conditions like ankylosing spondylitis, there is often an underlying dysregulation of immune responses, which can lead to increased susceptibility to infections or inflammatory conditions. This may manifest as recurrent glans inflammation or other dermatological issues. The inflammation could be due to a variety of factors, including infections (like yeast or bacterial infections), irritants, or even friction.
2. Persistent Red Spot: The persistent red spot you describe, which has not fully resolved despite treatment, could be indicative of several things. It may represent a localized inflammatory response, a remnant of previous inflammation, or even a scar. The fact that it is small and does not cause pain or itching is somewhat reassuring, but it is essential to monitor any changes. If the spot were to grow, change in color, or begin to cause discomfort, it would warrant further evaluation by a healthcare provider.
3. When to Seek Medical Attention: It is crucial to be vigilant about any changes in the lesion. You should seek medical attention if you notice:
- The spot increasing in size or changing in color.

- The development of pain, itching, or any discharge.

- Signs of bleeding or ulceration.

- Any systemic symptoms such as fever or malaise, which could indicate a more widespread infection or inflammatory process.

In the absence of these concerning symptoms, it may be reasonable to continue monitoring the spot while maintaining good hygiene and avoiding irritants. However, if you have any doubts or if the lesion persists without improvement, consulting a healthcare professional, preferably a dermatologist or urologist, would be advisable. They may perform a physical examination and possibly a biopsy if there is any concern about the nature of the lesion.

In summary, while autoimmune conditions can contribute to recurrent glans inflammation, the specific characteristics of your lesion and its behavior are essential in determining the next steps. Regular follow-ups and open communication with your healthcare provider are key to managing both your autoimmune condition and any related symptoms effectively.

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