Epididymitis Pain: When to Seek Further Testing - Urology

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Epididymal pain or discomfort?


Hello Doctor, I recently experienced discomfort at the urethral opening and swelling of the epididymis, so I visited a urologist.
After examination, I was diagnosed with urethritis caused by Chlamydia infection.
After about 10 days of antibiotic treatment, the discomfort in the epididymis has decreased, and the Chlamydia DNA test conducted the day after completing the treatment came back negative.
However, I still occasionally feel a burning sensation when urinating, and there is still some discomfort in the left epididymis.
Should I get tested for Mycoplasma or Ureaplasma infections, or is this just a psychological effect during the recovery period?

Xiang, 20~29 year old female. Ask Date: 2024/04/22

Dr. Jian Weihong reply Urology


Hello: If the epididymis is still swollen or painful, you should seek medical attention for further evaluation.
As for examinations and tests, they are for reference and can be determined by the physician.
They are not mandatory.
Wishing you good health.

Reply Date: 2024/04/22

More Info


Epididymitis, an inflammation of the epididymis, can be a distressing condition, particularly when accompanied by symptoms such as discomfort in the urethra and swelling of the epididymis. In your case, it appears that you have already undergone treatment for a Chlamydia infection, which is a common cause of epididymitis, particularly in younger males. After completing a 10-day course of antibiotics, you noted an improvement in symptoms, but residual discomfort in the left epididymis and occasional burning during urination persists.

Given your situation, it is essential to consider several factors before deciding on further testing. First, it is not uncommon for patients to experience lingering symptoms even after successful treatment of an infection. This can be due to several reasons, including:
1. Residual Inflammation: After an infection has been treated, inflammation may take some time to resolve completely. The tissues in the epididymis can remain sensitive and swollen for a period, leading to discomfort.

2. Psychological Factors: Anxiety about the condition and its implications can sometimes exacerbate the perception of pain or discomfort. This is often referred to as "psychosomatic" pain, where psychological factors contribute to physical symptoms.

3. Other Infections: While your recent DNA test for Chlamydia returned negative, it is prudent to consider other potential infections. Mycoplasma and Ureaplasma are less commonly tested but can also cause urethritis and epididymitis. If your symptoms persist, it may be worthwhile to discuss with your healthcare provider the possibility of testing for these organisms.

4. Chronic Epididymitis: In some cases, epididymitis can become chronic, where symptoms persist for more than six weeks despite treatment. This may require a different approach to management, including possible imaging studies or a referral to a urologist for further evaluation.

5. Other Causes: It is also important to rule out other potential causes of your symptoms, such as trauma, hernia, or even referred pain from other areas.

In summary, if your symptoms of burning during urination and discomfort in the left epididymis continue, it would be advisable to follow up with your healthcare provider. They may recommend further testing for Mycoplasma or Ureaplasma, or possibly imaging studies to assess the epididymis and surrounding structures. It is crucial to communicate all your symptoms and concerns during this follow-up visit, as this will help guide the appropriate next steps in your care.

Additionally, maintaining open communication with your healthcare provider about your symptoms and any concerns you have can help alleviate anxiety and ensure you receive the most appropriate care. Remember, it is always better to seek clarification and further evaluation if you feel that your symptoms are not resolving as expected. Your health and well-being should always be the priority.

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