Fundic Gland Polyps: What You Need to Know After Your Endoscopy - Gastroenterology and Hepatology

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Fundic gland polyp


Hello Doctor: I underwent an upper gastrointestinal endoscopy last week and found a gastric polyp approximately 1 cm in size.
This week, I received the report indicating it is a fundic gland polyp.
The report states: MICROSCOPIC DESCRIPTION: The section shows a fundic gland polyp composed of compact oxyntic glands with the presence of prominent microcysts lined by atrophic parietal and chief cells.
No intestinal metaplasia is seen.
No Helicobacter pylori bacilli in the foveolar pits can be found.
There is no epithelial dysplasia nor evidence of malignancy.
Can I feel reassured about this, Doctor?

Nìngmíng, 40~49 year old female. Ask Date: 2024/04/23

Dr. Lin Minghui reply Gastroenterology and Hepatology


This report indicates gastric fundic gland polyps, with no intestinal metaplasia, no Helicobacter pylori, no cellular atypia, and no malignancy.
You can rest assured.
Please follow up as per medical advice.
Wishing you good health!

Reply Date: 2024/04/23

More Info


Fundic gland polyps (FGPs) are a type of gastric polyp that typically arise from the gastric mucosa, particularly in the fundus of the stomach. Your recent endoscopy report indicates that you have a fundic gland polyp measuring approximately 1 cm, and the microscopic examination shows that it is composed of compact oxyntic glands with no signs of dysplasia or malignancy. This is reassuring, as FGPs are generally considered benign lesions.


Understanding Fundic Gland Polyps
1. Nature of Fundic Gland Polyps: FGPs are often associated with conditions such as chronic gastritis, particularly in patients with long-term use of proton pump inhibitors (PPIs). They are characterized by the proliferation of gastric foveolar cells and are typically non-cancerous. The absence of intestinal metaplasia and Helicobacter pylori in your biopsy results further supports the benign nature of your polyp.

2. Cancer Risk: The risk of FGPs progressing to gastric cancer is extremely low. Unlike adenomatous polyps, which have a higher potential for malignant transformation, FGPs do not exhibit this risk. The findings in your report indicate no dysplasia or malignancy, which is a positive sign.
3. Follow-Up and Monitoring: While FGPs are benign, it is still essential to monitor them, especially if you have a history of gastric issues or other risk factors for gastric cancer. The general recommendation for follow-up endoscopy in patients with FGPs is typically every 3 to 5 years, depending on individual risk factors and the size of the polyps. Since your polyp is 1 cm, your healthcare provider may recommend a follow-up in a shorter timeframe, such as 1 to 3 years, to ensure that there are no changes.

4. Symptoms and Management: If you experience symptoms such as abdominal pain, nausea, or changes in appetite, it is crucial to communicate these to your healthcare provider. While FGPs are usually asymptomatic, any new or worsening symptoms should be evaluated to rule out other gastrointestinal conditions.

5. Lifestyle and Prevention: Although FGPs themselves are not cancerous, maintaining a healthy lifestyle can contribute to overall gastric health. This includes a balanced diet rich in fruits and vegetables, regular exercise, and avoiding excessive alcohol and tobacco use. Additionally, if you are on PPIs, discuss with your doctor the necessity and duration of this treatment, as long-term use can be associated with the development of FGPs.


Conclusion
In summary, your recent endoscopy findings are reassuring, and the characteristics of the fundic gland polyp suggest that it is benign with a very low risk of malignancy. Regular follow-up with your healthcare provider is essential to monitor any changes. If you have any concerns or experience new symptoms, do not hesitate to reach out for further evaluation. Your health and peace of mind are paramount, and staying informed about your condition is a crucial part of managing your gastric health.

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