Lymphoma: Treatment Options and Care for Elderly Patients - Oncology

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Regarding lymphoma?


Hello Doctor, my grandfather was recently diagnosed with lymphoma.
However, the doctor advised against surgery due to concerns about infection.
Could you explain why? Wouldn't the cure rate be higher if surgery were performed? Additionally, the doctor mentioned chemotherapy, but my grandfather is quite old, and I've heard that chemotherapy can be very painful.
Could you please tell me what the chances of a cure are? Also, how should we take care of my grandfather? Thank you.

Binggan, 20~29 year old female. Ask Date: 2004/02/25

Dr. Lin Zongzhe reply Oncology


Hello: Surgery for lymphoma generally does not improve the cure rate; chemotherapy is the primary treatment for most lymphomas.
The cure rate is determined by prognostic factors such as the patient's overall health, the classification of the cancerous tissue, and the clinical stage.
Although chemotherapy can be more challenging for older patients, lymphoma has a significant chance of being cured.
Refusing chemotherapy due to harmful side effects is akin to throwing away an opportunity.
It is advisable to discuss the benefits and risks of treatment in detail with the attending physician, rather than giving up on beneficial treatment based on hearsay that "chemotherapy is very painful." Sincerely, Dr.
Lin Tsung-Che, Department of Oncology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2004/02/25

More Info


Lymphoma is a type of cancer that originates in the lymphatic system, which is part of the body's immune system. It primarily affects lymphocytes, a type of white blood cell that plays a crucial role in fighting infections. There are two main types of lymphoma: Hodgkin lymphoma and non-Hodgkin lymphoma, each with different characteristics, treatment protocols, and prognoses.

When it comes to treatment options for elderly patients, particularly those like your grandfather, several factors must be considered, including the specific type of lymphoma, the stage of the disease, and the overall health and functional status of the patient. In many cases, surgery is not the first line of treatment for lymphoma. This is primarily because lymphoma is often systemic, meaning it can affect multiple lymph nodes and organs throughout the body, rather than being localized to one area. Therefore, surgical removal of a tumor may not be effective or necessary.

Your grandfather's doctor may have recommended against surgery due to concerns about infection and complications that can arise from surgical procedures, especially in older patients who may have comorbidities or a weakened immune system. Surgery can pose significant risks, including prolonged recovery times and the potential for post-operative infections, which can be particularly dangerous for elderly patients.

Chemotherapy is often the preferred treatment for lymphoma, especially in cases where the disease is widespread. While it is true that chemotherapy can be challenging and may cause side effects such as nausea, fatigue, and hair loss, it is also a highly effective treatment that can lead to remission. The decision to pursue chemotherapy should be made collaboratively between the patient, family, and healthcare team, taking into account the potential benefits and risks.

Regarding the prognosis, the cure rate for lymphoma can vary significantly based on several factors, including the type of lymphoma, the stage at diagnosis, and the patient's overall health. In general, younger patients tend to have better outcomes, but many elderly patients also respond well to treatment. For instance, non-Hodgkin lymphoma can have a wide range of outcomes, with some subtypes being more aggressive than others. It's essential to discuss with your grandfather's oncologist to get a clearer picture of his specific situation and prognosis.

As for caring for your grandfather during treatment, here are some general recommendations:
1. Supportive Care: Ensure he has a comfortable and supportive environment. This includes managing any side effects from treatment, such as nausea or fatigue. Encourage him to rest and provide nutritious meals to help maintain his strength.

2. Emotional Support: Cancer treatment can be emotionally taxing. Be there to listen and provide emotional support. Encourage him to express his feelings and concerns.

3. Regular Communication with Healthcare Providers: Keep in close contact with his healthcare team. Attend appointments with him, ask questions, and ensure you understand his treatment plan and any necessary follow-up care.

4. Monitor for Side Effects: Be vigilant for any side effects from chemotherapy, such as signs of infection (fever, chills), unusual bruising or bleeding, or severe fatigue. Report any concerning symptoms to his doctor promptly.

5. Encourage Physical Activity: If he is able, encourage light physical activity, as it can help improve mood and overall well-being.

6. Educate Yourself: Learn as much as you can about lymphoma and its treatment options. This knowledge can empower you to make informed decisions and provide better support.

In conclusion, while the journey ahead may be challenging, many patients with lymphoma can achieve remission and lead fulfilling lives post-treatment. Open communication with healthcare providers and a strong support system can significantly impact your grandfather's experience and outcomes.

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