Addressing Concerns in Multiple Myeloma Treatment: A Patient's Journey
Questions Regarding Treatment of Multiple Myeloma Hello Dr. Hu, My mother is 67 years old and has been diagnosed with multiple myeloma through spinal cord testing, with a high IgD level (6000-7000). Other body metrics are mostly normal, with the only notable abnormality being a...
Dr. Hu Ziren Reply:
If it is caused by Sider, typically after 1-2 months of adapting to the medication treatment, symptoms will gradually improve. If it does not affect daily life, it is recommended to simply monitor the situation.[Read More] Addressing Concerns in Multiple Myeloma Treatment: A Patient's Journey
High Immunoglobulin Levels: Potential Indicators of Blood Disorders
Elevated immunoglobulin levels? The health check results show elevated immunoglobulin levels, with total protein at 6.8 g/dL, albumin at 4.6 g/dL, and globulin at 2.2 g/dL (highlighted in red). A subsequent blood test revealed IgG at 968 mg/dL, IgA at 206 mg/dL, and IgM at 261 mg...
Dr. Chen Yunfang Reply:
Hello: Free kappa 11.83, Free lambda 1.54, Kappa/lambda ratio 7.68. Only this ratio is abnormal; the standard K/L ratio is 1/1. All other values you provided are normal (however, we cannot draw conclusions as the lab report you provided is incomplete). I cannot give recommendatio...[Read More] High Immunoglobulin Levels: Potential Indicators of Blood Disorders
Understanding the Link Between Gamma-Globulin Levels and Multiple Myeloma
Possible multiple myeloma? Hello, doctor. I was diagnosed with COVID-19 on June 10. After that, on June 25, I developed petechiae on my calves due to an immune response. I sought medical attention, and it was assessed as vasculitis. Blood tests and urinalysis were all normal. Aft...
Dr. Chen Yunfang Reply:
Hello: You have undergone many tests, including some uncommon ones, which were not originally conducted due to a suspicion of multiple myeloma. Therefore, it is quite strange to force a connection to that. The diagnosis of multiple myeloma can only be made through a bone marrow a...[Read More] Understanding the Link Between Gamma-Globulin Levels and Multiple Myeloma
Understanding IFE Results: Can They Rule Out Multiple Myeloma?
IFE electrophoresis analysis Hello, doctor. I am the person who inquired about multiple myeloma last time. My IFE electrophoresis results showed no monoclonal protein present. Does this mean that multiple myeloma can be ruled out? Should I be concerned about MGUS?
Dr. Hu Ziren Reply:
Yes, multiple myeloma can be ruled out, including other plasma cell proliferative disorders (MGUS, etc.); please do not ask the same question again; if there are any issues related to testing, please discuss them with the primary physician.[Read More] Understanding IFE Results: Can They Rule Out Multiple Myeloma?
Understanding Blood Test Results: Insights on Multiple Myeloma and Related Conditions
Blood test report issues? Hello, doctor. I was diagnosed with COVID-19 on June 10. After that, on June 25, I developed petechiae on my calves due to an immune response. I sought medical attention, and it was assessed as vasculitis. I underwent blood tests and urinalysis, all of w...
Dr. Hu Ziren Reply:
If the Beta-microglobulin and FLC ratio (kappa/lambda) are normal, the possibility of multiple myeloma can be ruled out. Gamma globulin refers to immunoglobulins in the serum and is likely related to elevated RF IgM and cryoglobulin IgM levels. Note: Considering the above values,...[Read More] Understanding Blood Test Results: Insights on Multiple Myeloma and Related Conditions
Could My Symptoms Indicate Multiple Myeloma After COVID-19?
Multiple Myeloma Hello, doctor. Last month, after being diagnosed with COVID-19, I developed petechiae on my calves two weeks later. I went to the hospital, and the physician said it was vasculitis induced by the immune response after the infection. After taking steroids for a we...
Dr. Chen Sirong Reply:
Guang, 43 years old, male. Please forgive me, as I am not a hematology specialist. I recommend that you see a hematologist for blood tests. Wishing you good health. Taoyuan Hospital, Chen Si-Rong.[Read More] Could My Symptoms Indicate Multiple Myeloma After COVID-19?
Understanding Abnormal Blood Test Results: Is It Multiple Myeloma?
Abnormal blood test results? During a routine check-up, elevated total protein (TP) and globulin (GLO) levels were found, while other blood parameters were normal. The serum total protein was 8.7 g/dL, albumin (ALB) was 4.8 g/dL, and globulin was 3.9 g/dL. (Is this significantly ...
Dr. Chen Yunfang Reply:
Hello: You are too worried about whether you are ill. Tests are not infallible, and abnormalities do not necessarily indicate anything significant. Based on your description and reports, I do not have any recommendations. Thank you.[Read More] Understanding Abnormal Blood Test Results: Is It Multiple Myeloma?
Understanding Retinal Issues in Multiple Myeloma Patients: Symptoms and Solutions
Multiple myeloma causing retinal issues? Hello Doctor, I was diagnosed with multiple myeloma about two years ago, and after treatment, my symptoms stabilized for a year. Recently, however, my left eye suddenly became blurry and I couldn't see clearly. I visited the ophthalmo...
Dr. Chen Sirong Reply:
Zhang Ren'an / 72 years old / Male Your questions may exceed my ability to answer, please forgive me. 1. Are there more definitive examination methods for these eye symptoms? (e.g., fluorescein angiography) A: This should be directed to an ophthalmologist. The hematologi...[Read More] Understanding Retinal Issues in Multiple Myeloma Patients: Symptoms and Solutions
Understanding Anemia: Insights from Four Blood Tests and Gastrointestinal Issues
Anemia status from four blood test reports? Hello, Doctor. I have had a total of four blood tests from last year to this year. In March of last year: Red blood cell count: 4.6 (4.5-5.9), Hemoglobin: 13.6 (13.5-17.5), Hematocrit: 41 (41-53), Mean corpuscular volume: 87 (80-100), G...
Dr. Chen Yunfang Reply:
Hello: To me, your report is considered normal, and I will directly dismiss it in the outpatient clinic. The numbers are not fixed values; this is quite common. Thank you.[Read More] Understanding Anemia: Insights from Four Blood Tests and Gastrointestinal Issues
Understanding Monoclonal Gammopathy: Risks and Management Strategies
Unexplained monoclonal protein abnormalities My mother was informed during a blood test at Taipei Veterans General Hospital that her IgG levels were elevated (first test 1685, second test 1698) and her Kappa/Lambda ratio (approximately 20 in the first test, about 22 in the second...
Dr. Hu Ziren Reply:
This condition cannot be prevented; subsequent follow-up is more important. If concerned, it is advisable to return for a check-up every six months. If any of the following situations occur, it is recommended to schedule an earlier appointment: worsening kidney function (decrease...[Read More] Understanding Monoclonal Gammopathy: Risks and Management Strategies
Managing Suspected Multiple Myeloma: Key Insights and Recommendations
Management of suspected multiple myeloma? Hello, my father is 64 years old. Recently, a blood test revealed a hemoglobin level of 9.4 gm/dL. Despite multiple blood transfusions, his hemoglobin remains below 10 gm/dL, prompting further examination. The results showed the following...
Dr. Chen Yunfang Reply:
Hello: 1. Have you confirmed a diagnosis of multiple myeloma? So you received a major illness certificate? Based on your statement, it is impossible because a bone marrow aspiration has not been performed! Without a bone marrow aspiration, a diagnosis of myeloma cannot be made. A...[Read More] Managing Suspected Multiple Myeloma: Key Insights and Recommendations
Understanding Causes of Normocytic Anemia: Is It Myeloma or Throat Bleeding?
The causes of normocytic anemia can vary, but in your case, the most likely reasons could include chronic disease, acute blood loss, or renal insufficiency? Hello Doctor, on August 22nd of this year, I suddenly experienced significant bleeding from my throat, with more than four ...
Dr. Hu Ziren Reply:
Causes of normocytic anemia may include bleeding or hemolysis; it appears to be acute anemia caused by hematemesis. It is recommended to follow up with further testing after three months, provided there are no discomforting symptoms.[Read More] Understanding Causes of Normocytic Anemia: Is It Myeloma or Throat Bleeding?
Caring for Grandma with Multiple Myeloma: Dietary and Lifestyle Tips
Grandma has multiple myeloma? Recently, my grandmother was diagnosed with multiple myeloma, and it is now affecting her kidney function. What dietary and daily living recommendations do you have? My grandmother is in her 70s, and what kind of treatment options are typically consi...
Dr. Hu Ziren Reply:
Hello, if your grandmother's mobility is still relatively normal, it is recommended that she can undergo pharmacological treatment. In terms of diet, be cautious to avoid foods high in potassium and phosphorus, as well as medications that can harm the kidneys (such as certai...[Read More] Caring for Grandma with Multiple Myeloma: Dietary and Lifestyle Tips
Understanding Complications After Autologous Stem Cell Transplant for Multiple Myeloma
Multiple Myeloma 1: Hello Doctor, my family member is a 50-year-old male who was diagnosed with multiple myeloma last year. He completed an autologous stem cell transplant this Lunar New Year. Last month, during a follow-up visit, his blood test showed a hemoglobin level of 100 a...
Dr. Hu Ziren Reply:
You may try oral corticosteroids; if there is no improvement or if the condition worsens after 10 to 14 days, a referral to a dermatologist for a skin biopsy may be recommended.[Read More] Understanding Complications After Autologous Stem Cell Transplant for Multiple Myeloma
Assessing End-Stage Multiple Myeloma: Symptoms and Treatment Options
End-stage assessment of multiple myeloma? Dear Doctor, My father was diagnosed with stage II multiple myeloma six years ago at the age of 65. He did not undergo a stem cell transplant but chose treatment with CyBorD (cyclophosphamide, bortezomib, and dexamethasone). For the firs...
Dr. Chen Yunfang Reply:
Hello: 1. The original physician from Hospital L has returned, and the physician from Hospital Z has asked you to go back to the original hospital for treatment, so it’s quite clear where to go. 2. The symptoms of multiple myeloma are primarily related to the bone marrow. As the ...[Read More] Assessing End-Stage Multiple Myeloma: Symptoms and Treatment Options
Understanding Treatment Options and Prognosis for Multiple Myeloma
Treatment of Multiple Myeloma Hello Dr. Chen: My husband is 73 years old and was diagnosed with multiple myeloma last year. He has completed eight cycles of Velcade treatment and, after a two-month rest, his doctor performed another blood test, finding that his IgG level increase...
Dr. Chen Yunfang Reply:
Hello: 1. Regarding the first question, I cannot answer it because I do not know which stage your husband was in initially. 2. For the second question, besides Venclexta and Revlimid, commonly used medications for treating multiple myeloma include Thalidomide, Melphalan (Alke...[Read More] Understanding Treatment Options and Prognosis for Multiple Myeloma
Understanding Multiple Myeloma: Treatment Options and Concerns
Multiple Myeloma My father was diagnosed with multiple myeloma in mid-last year, with an initial IgG level of over 3000. After completing treatment with Velcade, his IgG level dropped to over 1500 by early March. During a follow-up appointment at the end of April, the doctor info...
Dr. Chen Sirong Reply:
Ms. Chen / 47 years old / Female Hello, because I am a radiation oncology specialist, I must consult with a hematology oncology specialist before I can confidently respond to your questions. 1. If Rituximab is used so early, will there be a situation where there are no availabl...[Read More] Understanding Multiple Myeloma: Treatment Options and Concerns
Understanding Multiple Myeloma: Treatment Response and Maintenance Therapy
Multiple Myeloma Thank you for the response on May 4th. The IgG level decreased from 3480 mg/L before treatment to 1590 mg/L. If the units are as stated, does this indicate a complete remission of the treatment? If so, does the physician's subsequent use of Revlimid represen...
Dr. Lai Yicheng Reply:
Dear Ms. Chen, Thank you for your letter. Here is the response: The normal range for IgG is 690-1400 mg/dL. Your levels have decreased from 3480 mg/L to 1590 mg/L, indicating some improvement, but they are still above the standard value. The first-line treatment for multiple m...[Read More] Understanding Multiple Myeloma: Treatment Response and Maintenance Therapy
Understanding Multiple Myeloma Treatment: Questions About Therapy Options
Multiple Myeloma Dear Director, My father is seventy years old and was diagnosed with multiple myeloma last June. An X-ray report indicated that his bones were not affected. He began treatment with Velcade in late June last year, completing eight cycles by early March. His IgG l...
Dr. Lai Yicheng Reply:
Dear Ms. Chen, Thank you for your letter. Here are my responses: 1. Regarding your IgG level of 3480, the unit is either g/L or mg/L. If the unit is g/L, the current level of 1590 g/L is still too high, indicating that the treatment effect is not ideal, which is why the physici...[Read More] Understanding Multiple Myeloma Treatment: Questions About Therapy Options
Curcumin's Potential in Inhibiting Multiple Myeloma Growth: Current Insights
Multiple Myeloma I found research reports from the University of Texas MD Anderson Cancer Center and Virginia Tech regarding multiple myeloma, indicating that curcumin has the ability to inhibit the growth of cancer cells. Are there any clinical trial reports or information avail...
Dr. Lai Yicheng Reply:
Mr. Yan: Thank you for your letter. In response to your inquiry regarding the ability of curcumin to inhibit cancer cell growth, as you mentioned, there are relevant research reports from the University of Texas MD Anderson Cancer Center and Virginia Tech in the United States. Ho...[Read More] Curcumin's Potential in Inhibiting Multiple Myeloma Growth: Current Insights