Unexplained Body Pain: A Neurological Perspective - Neurology

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Physical changes in the past three months?


Hello, Doctor.
I have been experiencing various health issues over the past three months.
Initially, I had pain throughout my body (I'm unsure if it's muscle pain or bone pain).
The pain is difficult to describe; sometimes it feels like tenderness, and other times it feels like tingling.
Then I started having muscle twitching symptoms (which initially occurred randomly).
During this period, I have been continuously visiting doctors at both a large hospital (neurology department) and a small clinic (orthopedics).

In orthopedics, I mentioned pain in my arms and back, and they took X-rays of my neck, which they said looked fine, suggesting some neck stretching.
The neurology department believes I may be experiencing anxiety and suggested it resembles fibromyalgia (though no tests were conducted), prescribing anti-anxiety medication and medication to prevent muscle twitching, among other things.
However, I feel that my condition has not improved; in fact, I am more aware of the diverse sensations of pain in my body.

Sometimes my left and right legs hurt, with the left leg experiencing more pain.
Of course, the pain in my arms also occurs occasionally.
Regarding muscle twitching, I notice it more frequently in my left thigh (inner side) and left knee, as well as my left little toe.
My left knee often feels tight and weak.
Recently, I have also experienced a painful lump in the front of my calf that cramps (lasting no more than 30 seconds).
Whether sitting or standing, I feel a trembling sensation in my body (similar to the vibrations from a large vehicle passing by or the tremors before an earthquake).
Some aspects of my symptoms feel somewhat similar to conditions like amyotrophic lateral sclerosis (ALS), and I am unsure where to seek further evaluation or which specialty to consult.
I also struggle to express these unusual phenomena clearly.
I hope the doctor can provide some advice.

hone, 20~29 year old female. Ask Date: 2024/05/10

Dr. Huang Hongling reply Neurology


Fibromyalgia is diagnosed based on clinical symptoms, and some medications used for it also serve as treatments for anxiety or depression.
As for amyotrophic lateral sclerosis (ALS), pain is rarely a symptom.
It is recommended that you return to your original neurologist for a consultation and discuss your concerns with the physician.

Reply Date: 2024/05/10

More Info


Understanding unexplained body pain can be quite complex, especially when it involves a combination of symptoms such as muscle pain, tenderness, and involuntary muscle twitching. Your situation, characterized by a variety of pain sensations and muscle spasms, raises several important considerations from a neurological perspective.

Firstly, it’s crucial to recognize that pain can be categorized into different types: nociceptive pain (resulting from tissue damage), neuropathic pain (arising from nerve damage), and psychogenic pain (associated with psychological factors). Given your symptoms, it’s possible that you could be experiencing a combination of these pain types. For instance, the tenderness and pressure pain you describe may suggest a nociceptive component, while the muscle twitching could indicate a neuropathic origin.

The mention of anxiety by your neurologist is also significant. Anxiety can amplify the perception of pain and lead to a heightened awareness of bodily sensations, which may explain why you feel more attuned to your discomfort. Conditions such as fibromyalgia, which is characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood issues, could also be a consideration. Fibromyalgia is often associated with heightened sensitivity to pain and can be exacerbated by stress and anxiety.

In terms of diagnostic approaches, it’s essential to undergo a comprehensive evaluation to rule out any underlying medical conditions. This may include blood tests to check for inflammatory markers, vitamin deficiencies, or autoimmune disorders, as well as imaging studies like MRI or CT scans to assess for structural issues. A referral to a rheumatologist might also be beneficial, as they specialize in conditions that affect the muscles and joints.

You mentioned that you have been prescribed anti-anxiety medication and muscle relaxants, which can help manage symptoms but may not address the root cause of your pain. It’s important to communicate with your healthcare provider about the effectiveness of these treatments and any side effects you may be experiencing. If your symptoms persist or worsen, seeking a second opinion from another neurologist or a pain specialist could provide additional insights.

Additionally, consider exploring non-pharmacological interventions. Cognitive-behavioral therapy (CBT) can be effective in managing chronic pain and anxiety by helping you develop coping strategies and altering negative thought patterns. Physical therapy may also be beneficial, as it can help improve mobility, strengthen muscles, and reduce pain through targeted exercises.

Lastly, maintaining a healthy lifestyle, including regular physical activity, a balanced diet, and adequate sleep, can significantly impact your overall well-being and pain management. Mindfulness practices, such as yoga or meditation, may also help reduce anxiety and improve your pain perception.

In summary, your symptoms warrant a thorough investigation to identify any underlying causes and to develop a comprehensive treatment plan. Open communication with your healthcare providers, along with a multidisciplinary approach that includes both medical and psychological support, will be key in addressing your unexplained body pain effectively.

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