Unexplained Pain: Symptoms and Possible Causes - Internal Medicine

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Unexplained pain


In the past two weeks, I initially experienced headaches accompanied by weakness in my limbs, followed by dizziness (I consulted a neurologist, and the EEG was normal; the doctor mentioned it was due to high stress).
Additionally, there are some areas in my arms and legs that experience unexplained sharp pain (it feels like it's in the blood vessels), and I noticed bloodshot eyes; I visited an ophthalmologist who diagnosed me with conjunctivitis.
Recently, I've also been experiencing pain at the upper end of my femur (located in the hip area), which hurts when sitting.
Given all these symptoms, what could be the underlying cause? I do not have any fever symptoms.
Thank you for your assistance.

Xiao Wei, 20~29 year old female. Ask Date: 2004/05/30

Dr. Li Dong'an reply Internal Medicine


Hello, Xiao Wei: In addition to your symptoms, it is necessary to conduct a physical examination and laboratory tests to identify the underlying cause.
I recommend that you consult with specialists in immunology and rheumatology, as well as neurology, to rule out any issues related to vasculitis or inflammatory conditions.

Reply Date: 2004/05/30

More Info


Unexplained pain can be a complex and multifaceted issue, often requiring a thorough investigation to identify the underlying causes. Based on your symptoms, which include headaches, limb weakness, dizziness, unexplained pain in specific areas, and conjunctival injection (redness in the eye), it is essential to consider a range of potential diagnoses.

Firstly, the combination of headaches, dizziness, and limb weakness could suggest a neurological issue, even though your EEG results were normal. Conditions such as migraines, tension-type headaches, or even more serious concerns like multiple sclerosis or transient ischemic attacks (TIAs) could manifest with these symptoms. It is crucial to follow up with a neurologist if symptoms persist or worsen, as they may recommend further imaging studies, such as an MRI, to rule out structural abnormalities in the brain.

The unexplained pain in your limbs, particularly if it feels like it is located in the blood vessels, could be indicative of several conditions. One possibility is peripheral neuropathy, which can cause pain, tingling, or weakness in the extremities. This condition can arise from various factors, including diabetes, vitamin deficiencies, or autoimmune disorders. Another consideration is complex regional pain syndrome (CRPS), which can develop after an injury and lead to chronic pain, swelling, and changes in skin color or temperature.

The eye symptoms you described, particularly the conjunctival injection, suggest an inflammatory process, such as conjunctivitis. While this is often benign, it can sometimes be associated with systemic conditions, including autoimmune diseases. If you have not already done so, it may be beneficial to consult with an ophthalmologist for a comprehensive eye examination and to rule out any underlying issues.

Regarding the pain in your hip area, particularly when sitting, this could be related to musculoskeletal issues, such as bursitis or tendinitis, or even referred pain from spinal issues. Conditions like sciatica, where nerve pain radiates from the lower back to the legs, could also be a factor. A physical examination and possibly imaging studies like X-rays or MRI of the hip and lower back may be warranted to assess for any structural problems.

In summary, your symptoms are indicative of a potential interplay between neurological, musculoskeletal, and possibly systemic inflammatory processes. It is essential to maintain open communication with your healthcare providers and advocate for further evaluation if your symptoms do not improve or if new symptoms arise. Keeping a detailed symptom diary, including when symptoms occur and any potential triggers, can be helpful for your doctors in diagnosing your condition.
Additionally, managing stress through relaxation techniques, physical therapy, or counseling may also be beneficial, especially if stress is contributing to your symptoms. Remember, it is crucial to seek a comprehensive evaluation from specialists who can work together to provide a holistic approach to your care.

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