Platelet Distribution Width and Its Implications for Health - Family Medicine

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Platelet distribution width (PDW)


Hello, Doctor.
I have a few questions I would like to ask you: A few days ago, I went to the hospital to check my blood test results.
The doctor mentioned that overall, the values suggest iron deficiency anemia (microcytic), but my hemoglobin level is still at 10.3.
He believes that further blood tests are unnecessary (the doctor said symptoms become significant when hemoglobin is < 9).
However, I often experience dizziness and nausea (for example, just turning my body around once makes me feel dizzy and nauseous).
Although I can manage it by resting a bit, is this situation still considered normal? Or are there other aspects that need to be checked beyond just anemia? P.S.
Overall, my values are slightly worse than in previous years (the anemia-related numbers have all decreased).
Additionally, the doctor did not mention it at the time, but when I reviewed the report at home, I noticed that the "platelet distribution width" value was marked as "unable to be interpreted by the instrument." What does this mean? (I had a complete blood count, and about 5 tubes of blood were drawn.) Lastly, the report indicates "bilirubin positive 1" under "blood observation." What does this mean? Thank you very much for taking the time to respond!

Niming, 20~29 year old female. Ask Date: 2024/05/16

Dr. Liao Yaopan reply Family Medicine


Hello,
1.
It is recommended to clarify the causes of anemia before reassessing the need for immediate treatment.

2.
The width of platelet distribution may be related to the differences in the size of blood cells.
It is advised to consult a hematology outpatient clinic regarding these two issues.

3.
Jaundice still requires reliance on other biochemical tests; online consultations are not equivalent to in-person visits and cannot provide diagnostic or treatment recommendations.

Changhua Hospital cares about you.

Reply Date: 2024/05/16

More Info


Understanding Platelet Distribution Width (PDW) and Its Implications for Health
Platelet Distribution Width (PDW) is a measure of the variability in the size of platelets in the blood. It is an important parameter in a complete blood count (CBC) and can provide insights into various health conditions. A high PDW indicates a greater variation in platelet size, which may suggest an underlying health issue, while a normal PDW suggests a more uniform platelet population.

In your case, the mention of "instrument unable to interpret" regarding your PDW value indicates that the laboratory equipment could not provide a reliable measurement. This could be due to several factors, including the quality of the blood sample, the presence of clumped platelets, or technical issues with the testing equipment. It is essential to discuss this with your healthcare provider, as they may recommend a repeat test to obtain a valid PDW measurement.

Regarding your symptoms of dizziness and nausea, especially when turning your body, it is crucial to consider that while your hemoglobin level of 10.3 g/dL is above the threshold of 9 g/dL, it is still indicative of mild anemia. Symptoms like dizziness can occur even with mild anemia, particularly if your body is not adequately compensating for the reduced oxygen-carrying capacity of your blood. Other factors, such as hydration status, blood pressure, and overall cardiovascular health, can also contribute to these symptoms. Therefore, it would be prudent to monitor your symptoms closely and discuss them with your doctor, who may consider further evaluations or referrals to specialists if necessary.

The presence of jaundice (indicated by "jaundice positive 1+") in your blood report suggests that there may be an increased level of bilirubin in your blood, which can occur due to various reasons, including liver dysfunction, hemolysis (breakdown of red blood cells), or bile duct obstruction. Jaundice can also be associated with certain types of anemia, including hemolytic anemia, where the body destroys red blood cells faster than they can be produced. Given your symptoms and the findings in your blood tests, it would be advisable to have a thorough evaluation of your liver function and a complete hemolytic workup to determine the underlying cause of your jaundice.

In summary, PDW is a valuable parameter in assessing platelet function and can indicate various health issues. The inability to interpret your PDW value warrants further investigation. Your symptoms of dizziness and nausea, combined with mild anemia and jaundice, suggest that a comprehensive evaluation is necessary to rule out any significant underlying conditions. It is essential to maintain open communication with your healthcare provider and follow up on these findings to ensure appropriate management of your health concerns.

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