Do Seladin and Labtal Cause Low Blood Pressure? A Doctor's Insight - Family Medicine

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Hello, doctor.
I would like to ask whether the medications Seladin and Labtal can cause a decrease in blood pressure.
My blood pressure was already low, and it has become even lower after taking them.
This issue has been troubling me for a long time.
Thank you for your help in answering this.

An An, 40~49 year old female. Ask Date: 2024/06/09

Dr. Cai Dongqi reply Family Medicine


Hello, labtal is available, but seladin is not.

Reply Date: 2024/06/09

More Info


Seladin (also known as Selegiline) and Labtal (which is likely a reference to Labetalol) are two medications that can have different effects on blood pressure. Understanding their pharmacological profiles is essential for addressing your concerns about low blood pressure.

Seladin (Selegiline) is primarily used as a treatment for Parkinson's disease and major depressive disorder. It works as a selective monoamine oxidase B (MAO-B) inhibitor, which increases the levels of certain neurotransmitters in the brain, such as dopamine. While Selegiline is not typically associated with causing low blood pressure, it can have side effects that may indirectly affect blood pressure regulation, particularly in sensitive individuals or when combined with other medications. However, it is generally not known to lower blood pressure significantly.

Labtal (Labetalol), on the other hand, is a medication that is commonly used to treat high blood pressure (hypertension). It is a combined alpha and beta-adrenergic blocker, which means it can lower blood pressure by reducing heart rate and dilating blood vessels. As a result, Labetalol can indeed cause a decrease in blood pressure, especially in individuals who are already on the lower side of the blood pressure spectrum. If you were already experiencing low blood pressure before starting Labetalol, it is possible that this medication could exacerbate that condition.

In your case, if you have noticed a significant drop in blood pressure after starting these medications, it is crucial to discuss this with your healthcare provider. They can evaluate your overall health, review your medication regimen, and determine whether adjustments are necessary. It is also important to monitor your blood pressure regularly, especially if you are experiencing symptoms such as dizziness or lightheadedness.

Low blood pressure (hypotension) can lead to various symptoms, including dizziness, fainting, and fatigue. If your blood pressure readings are consistently low, your doctor may consider several factors, including your overall health, any underlying conditions, and the potential interactions between medications.
In managing low blood pressure, your healthcare provider may suggest lifestyle modifications, such as increasing fluid and salt intake (if appropriate), wearing compression stockings, or adjusting your medications. In some cases, medications that raise blood pressure may be prescribed if lifestyle changes are insufficient.

Additionally, it is essential to consider other possible causes of low blood pressure, such as dehydration, blood loss, or certain medical conditions. If you have a history of heart problems or other health issues, these could also contribute to fluctuations in your blood pressure.

In summary, while Seladin is not typically associated with low blood pressure, Labtal can lower blood pressure and may be contributing to your symptoms. It is essential to have an open dialogue with your healthcare provider to ensure that your treatment plan is safe and effective for your specific situation. Regular monitoring and adjustments may be necessary to maintain optimal blood pressure levels and overall health.

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