Persistent Urgency to Urinate: When to Test After Levofloxacin? - Urology

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Still experiencing a persistent urge to urinate?


If I have been taking Levofloxacin 750 mg for one month but still have a persistent urge to urinate without any other pain, and the doctor seems to suggest stopping the medication after one month, how many days after stopping the medication should I wait before testing for bacteria and other sexually transmitted infections to ensure accurate results for blood and urine tests?

Wei, 30~39 year old female. Ask Date: 2024/06/11

Dr. Du Shixi reply Urology


Hello: If symptoms persist after a period of treatment, it may be necessary to consult your physician about the addition of other medications.
Additionally, dietary considerations are important; limit the intake of beverages and focus on drinking plain water, while also minimizing the consumption of diuretic foods.

Reply Date: 2024/06/11

More Info


When it comes to persistent urinary urgency after a course of Levofloxacin, it's important to understand both the medication's effects and the appropriate timing for testing after discontinuation. Levofloxacin is a fluoroquinolone antibiotic commonly used to treat various bacterial infections, including urinary tract infections (UTIs). If you've been taking Levofloxacin for a month and are still experiencing persistent urgency to urinate without other pain, it may indicate that the underlying issue has not been fully resolved or that there could be another cause for your symptoms.

After stopping Levofloxacin, the timing for accurate urine and blood tests can vary. Generally, it is advisable to wait at least 48 to 72 hours after discontinuing the antibiotic before conducting urine tests for bacterial cultures. This waiting period allows any residual effects of the antibiotic to diminish, ensuring that the test results accurately reflect the presence of bacteria in the urine. If you are also considering testing for sexually transmitted infections (STIs), it is typically recommended to wait at least one week after stopping antibiotics to ensure that the results are not influenced by the medication.

In your case, since you've been experiencing persistent urinary urgency, it would be prudent to follow up with your healthcare provider. They may recommend additional tests to rule out other potential causes of your symptoms, such as interstitial cystitis, bladder irritation, or other infections that may not be responsive to Levofloxacin. It's also important to consider lifestyle factors, such as hydration and dietary choices, which can influence urinary symptoms. Drinking plenty of water and avoiding irritants like caffeine and alcohol may help alleviate some of the urgency.

If your symptoms persist despite the completion of the antibiotic course, your doctor may consider alternative treatments or further diagnostic evaluations, such as imaging studies or cystoscopy, to investigate the underlying cause of your urinary urgency. It's essential to communicate openly with your healthcare provider about your symptoms and any concerns you may have regarding the treatment plan.

In summary, after stopping Levofloxacin, waiting 48 to 72 hours before testing for bacterial infections is advisable, while a week may be more appropriate for STI testing. Persistent urinary urgency warrants further evaluation, and maintaining open communication with your healthcare provider is crucial for effective management of your symptoms.

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