Ergometrine: Uses, Side Effects, and Concerns - Obstetrics and Gynecology

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Ergonovine is a uterotonic medication?


Hello Dr.
Tsao,
On June 14 (Friday), I underwent a medical abortion.
Aside from experiencing significant pain and passing blood clots that day, I did not have much discomfort in the following days.
However, yesterday, June 18, I suddenly experienced abdominal pain and passed a large blood clot, which prompted me to visit a clinic.
The physician prescribed Ergometrine 0.2 mg for uterine contractions, to be taken four times a day.
Since I started taking it yesterday, I have been experiencing swelling and pain in my thighs and calves, but I have not engaged in any physical activity aside from visiting the doctor.
1.
Could this be a side effect of the medication?
2.
I previously had mild proteinuria and hematuria during a health check-up.
Could this medication be affecting my kidney function?
3.
I have one more day's worth of medication left.
Should I finish it?
Thank you for your patient response.

Yun, 30~39 year old female. Ask Date: 2024/06/18

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, this medication generally does not affect other functions.
If you are still feeling unwell, it would be best to return to the obstetrics and gynecology department for an examination.
Wishing you good health.

Reply Date: 2024/06/18

More Info


Ergometrine, also known as ergonovine, is a medication primarily used to stimulate uterine contractions. It is often prescribed after childbirth or abortion to help the uterus return to its normal size and to reduce the risk of excessive bleeding. While it can be effective in managing these conditions, it is important to be aware of its potential side effects and interactions with other medications.


Uses of Ergometrine
1. Uterine Contraction: Ergometrine is commonly used to promote uterine contractions after delivery or abortion, which helps to expel any remaining placental tissue and reduces the risk of postpartum hemorrhage.

2. Management of Postpartum Hemorrhage: It is particularly useful in cases where there is a risk of significant blood loss after childbirth.


Side Effects
While ergometrine can be beneficial, it is not without side effects. Common side effects include:
- Gastrointestinal Issues: Nausea, vomiting, and abdominal pain are frequently reported.

- Cardiovascular Effects: It may cause an increase in blood pressure and can lead to palpitations or changes in heart rate.

- Neurological Symptoms: Headaches, dizziness, and a sensation of tingling or numbness can occur.

- Muscle Pain: Some patients report muscle cramps or pain, particularly in the legs, which may be related to the medication's effects on blood vessels.

In your case, the swelling and pain in your legs could potentially be linked to the use of ergometrine, especially if you have been relatively inactive. This medication can cause vasoconstriction, which may lead to reduced blood flow and subsequent discomfort in the extremities.


Concerns Regarding Kidney Function
Regarding your previous health check showing mild proteinuria and hematuria, it is essential to consider that ergometrine is not typically known to directly affect kidney function. However, any medication that influences blood pressure can indirectly impact renal function, particularly in individuals with pre-existing kidney issues. If you experience significant changes in urination, swelling, or any other concerning symptoms, it is crucial to consult your healthcare provider.


Recommendations
1. Continue Medication: If your doctor prescribed ergometrine, it is generally advisable to complete the prescribed course unless you experience severe side effects. However, if the discomfort in your legs becomes intolerable or if you have other concerning symptoms, you should reach out to your healthcare provider for further evaluation.


2. Monitoring Symptoms: Keep track of any new or worsening symptoms, especially those related to swelling, pain, or changes in urination. This information will be valuable for your healthcare provider in assessing your condition.

3. Follow-Up Appointment: Given your recent symptoms and history, it may be beneficial to schedule a follow-up appointment with your doctor to discuss your concerns and possibly adjust your treatment plan.


Conclusion
Ergometrine is a valuable medication for managing uterine contractions and preventing postpartum complications. However, it is essential to be vigilant about its side effects and to communicate openly with your healthcare provider about any concerns. Your health and comfort should always be the priority, and your doctor can provide the best guidance tailored to your specific situation.

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