Managing Blood Sugar and Kidney Health: A Patient's Journey - Family Medicine

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Blood Sugar and Kidney Issues


Hello doctor, a month ago my fasting blood glucose was 127, and my HbA1c was 7.2.
The doctor prescribed medication for me, but I was advised not to take it.
Instead, I focused on exercising and changing my diet, and my fasting blood glucose has mostly been between 100 and the low 110s.
Recently, I went to a lab and my HbA1c dropped to 6.1.
However, my glomerular filtration rate (GFR) was in the 80s four months ago, in the 70s a month ago, and now it has dropped to 62.
Why has my GFR decreased so rapidly, even though my blood glucose levels have improved? What should I do?

Jayen288, 50~59 year old female. Ask Date: 2024/07/10

Dr. Lin Zhebin reply Family Medicine


Hello: The decrease in your glomerular filtration rate may be due to diabetic nephropathy or other factors causing kidney damage (such as dehydration, use of pain medications, etc.).
It is recommended that you see a nephrologist as soon as possible for further evaluation of the underlying cause.

Reply Date: 2024/07/10

More Info


Managing blood sugar levels and maintaining kidney health are critical components of overall health, especially for individuals with diabetes. Your recent journey, marked by a notable improvement in your glycosylated hemoglobin (HbA1c) levels, is commendable. However, the decline in your glomerular filtration rate (GFR) raises important concerns that warrant further exploration.

Firstly, let's discuss the significance of your blood sugar levels. A fasting blood sugar of 127 mg/dL and an HbA1c of 7.2% indicate that you were in the prediabetic range, which is a critical stage where lifestyle changes can significantly impact your health trajectory. Your efforts in exercising and modifying your diet have evidently paid off, as reflected in your recent HbA1c of 6.1%. This is a significant achievement, as it suggests that you are effectively managing your blood sugar levels, which is crucial in preventing long-term complications associated with diabetes, including kidney disease.

However, the decline in your GFR from the 80s to 62 mL/min is concerning. The GFR is a key indicator of kidney function, and a decrease can suggest that the kidneys are not filtering blood as efficiently as they should. Several factors could contribute to this decline:
1. Diabetes and Kidney Health: Diabetes is a leading cause of chronic kidney disease (CKD). Over time, high blood sugar levels can damage the blood vessels in the kidneys, leading to decreased function. Even with improved blood sugar control, existing damage may still affect kidney function.

2. Blood Pressure: High blood pressure often accompanies diabetes and can further damage the kidneys. It is essential to monitor and manage blood pressure levels, ideally keeping them below 130/80 mmHg.

3. Dehydration or Acute Illness: If you have experienced any recent illnesses, dehydration, or changes in medication, these could also impact kidney function temporarily.

4. Dietary Factors: While you are making positive changes, it is crucial to ensure that your diet is not excessively high in protein or sodium, as these can strain the kidneys.

5. Medication Effects: If you are taking any medications, some can affect kidney function. It is essential to discuss your medications with your healthcare provider to ensure they are appropriate for your kidney health.

Given these factors, it is vital to take a proactive approach:
- Regular Monitoring: Continue to monitor your blood sugar levels and GFR regularly. This will help you and your healthcare provider identify any trends or changes that need to be addressed.

- Consult a Nephrologist: Given the decline in your GFR, it would be wise to consult a nephrologist (kidney specialist) who can provide a comprehensive evaluation of your kidney function and recommend appropriate interventions.

- Lifestyle Modifications: Maintain your focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins while limiting processed foods, sugars, and sodium. Regular physical activity is also crucial.

- Hydration: Ensure you are adequately hydrated, as dehydration can impact kidney function.

- Blood Pressure Management: If you have not already, monitor your blood pressure regularly and discuss with your doctor about potential medications or lifestyle changes to keep it in check.

In summary, while your progress in managing blood sugar is commendable, the decline in kidney function is a critical issue that requires attention. By working closely with your healthcare team, including a nephrologist, you can develop a comprehensive plan to protect your kidney health while continuing to manage your diabetes effectively. Remember, early intervention is key to preventing further complications.

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