Syphilis Treatment and Urological Issues After Cancer Surgery - Urology

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Infection issues


Dear Director: Thirty-eight years ago, I was unaware and contracted syphilis.
After taking traditional Chinese medicine for three months, I showed improvement and have not experienced significant issues, though I occasionally feel discomfort in my lower abdomen and urinary tract.
Recently, I underwent surgery for rectal cancer, which has weakened my immune system.
While researching, I found that the treatment for this condition is no longer as intensive as it used to be, requiring only two consecutive weeks of treatment.
Given that it has been such a long time, my lowered immunity, and the recent onset of symptoms like penile pain, would administering one to two doses of Bicillin L-A (penicillin G) be sufficient to resolve the issue? If there is a recurrence, what is the current complete treatment regimen? Thank you for your response!

GUNBEE, 50~59 year old female. Ask Date: 2024/07/12

Dr. Du Shixi reply Urology


Hello: You need to retest for syphilis markers.
If the results are normal, there is no need for an injection, as it may not necessarily be caused by syphilis.
Please go to the hospital for a blood test.
Wishing you good health.

Reply Date: 2024/07/12

More Info


Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It is important to understand that syphilis can have significant implications for both sexual health and overall well-being, especially in individuals with compromised immune systems, such as those recovering from cancer surgery.
Given your history of syphilis and recent cancer surgery, it is crucial to approach treatment with caution. Traditionally, the treatment for syphilis has involved the administration of penicillin, specifically Benzathine penicillin G (Bicillin L-A). The standard treatment regimen for early syphilis typically consists of a single intramuscular injection of Benzathine penicillin G. However, for late latent syphilis or tertiary syphilis, the treatment may require multiple doses over a period of weeks.

In your case, since you mentioned experiencing discomfort in the lower abdomen and symptoms such as penile pain, it is essential to consult with a healthcare provider for a thorough evaluation. Symptoms like these could indicate a resurgence of syphilis or other urological issues, which may require further investigation.
Regarding your question about the number of injections needed, the current guidelines suggest that for early syphilis, a single dose of Benzathine penicillin G is often sufficient. However, if there is a concern about reinfection or if you are experiencing symptoms suggestive of a syphilis relapse, your healthcare provider may recommend additional doses or a different treatment regimen.

It is also important to consider that your immune system may be compromised due to recent cancer surgery, which can affect how your body responds to infections and treatments. Therefore, it is crucial to have open communication with your healthcare provider about your medical history, current symptoms, and any concerns you may have regarding your immune status and treatment options.

In summary, if you suspect a recurrence of syphilis or are experiencing new symptoms, it is vital to seek medical attention promptly. Your healthcare provider can perform the necessary tests, including serological tests for syphilis, to confirm whether the infection has returned and to determine the appropriate treatment plan. They may also evaluate your overall health and immune function to tailor the treatment to your specific needs.
In conclusion, while a single injection of Benzathine penicillin G may be effective for early syphilis, your individual circumstances, including your cancer history and current symptoms, necessitate a personalized approach. Always consult with your healthcare provider for the best course of action.

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