Managing Liver Health: Alternatives to Hepatoprotective Medications - Gastroenterology and Hepatology

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Liver An-Neng


Hello, doctor! Last October, my liver enzyme levels were GOT 139 and GPT 293, and I visited the hospital (I am a carrier of Hepatitis B).
The doctor recommended taking Liv52, and I have been taking it since then.
However, Liv52 is not covered by health insurance, and my liver enzyme levels are now normal.
I have decided to stop the medication.
I would like to ask if, in such a situation, Liv52 or interferon are the only options to lower the enzyme levels? Are there any other medications that can be alternatives? If I stop the medication and my enzyme levels rise again, should I resume taking Liv52? Additionally, what are the differences between individuals with high enzyme levels who have Hepatitis B and those who do not? Thank you!

kk, 20~29 year old female. Ask Date: 2004/03/27

Dr. Liang Jiade reply Gastroenterology and Hepatology


Hello, (1) Is Hepatitis B medication covered by health insurance? Currently, under specific conditions, health insurance does provide coverage.
There are other medications for Hepatitis B, but they are only used in special circumstances, and health insurance has not yet provided coverage for them.
(2) A decision has been made to discontinue the medication.
Continuous monitoring through blood tests is necessary to avoid relapse after stopping the medication.
(3) If the levels rise again after discontinuation, it is essential to determine whether it is indeed caused by Hepatitis B or other reasons.
Further examination is needed to ascertain whether Hepatitis B medication is being taken.
(4) Elevated levels over a prolonged period indicate ongoing liver inflammation, which is detrimental and increases the risk of developing cirrhosis in the future.

Reply Date: 2004/03/27

More Info


Managing liver health, especially for individuals with chronic conditions like hepatitis B, requires a multifaceted approach that goes beyond just medication. While hepatoprotective medications such as Silymarin (often referred to as Milk Thistle) and antiviral treatments like interferon can play a role in managing liver health, lifestyle modifications and regular monitoring are equally crucial.


Understanding Hepatitis B and Liver Function
Hepatitis B is a viral infection that can lead to chronic liver disease, including cirrhosis and liver cancer. Elevated liver enzymes (GOT and GPT) indicate liver inflammation or damage, which can be exacerbated by various factors, including alcohol consumption, obesity, and certain medications. The presence of hepatitis B can complicate liver health management, as it may lead to chronic inflammation and fibrosis.


Alternatives to Hepatoprotective Medications
1. Dietary Changes: A balanced diet rich in fruits, vegetables, whole grains, and lean proteins can support liver health. Foods high in antioxidants, such as berries and leafy greens, can help reduce oxidative stress on the liver. Additionally, reducing saturated fats and sugars can help manage weight and decrease the risk of fatty liver disease.

2. Regular Exercise: Engaging in regular physical activity can help maintain a healthy weight, improve insulin sensitivity, and reduce liver fat. Aim for at least 150 minutes of moderate-intensity aerobic exercise each week, along with strength training exercises.

3. Avoiding Alcohol and Toxins: Alcohol can significantly worsen liver damage, especially in individuals with hepatitis B. It's crucial to avoid alcohol entirely or limit intake to very low levels. Additionally, be cautious with over-the-counter medications and herbal supplements, as some can be hepatotoxic.

4. Regular Monitoring: Regular follow-up appointments with a healthcare provider are essential for monitoring liver function and managing hepatitis B. Blood tests to check liver enzymes, viral load, and liver function should be performed as recommended by your physician.

5. Vaccinations: Ensure that you are vaccinated against hepatitis A and other preventable liver diseases. This can help reduce the risk of additional liver complications.


What to Do If Liver Enzymes Rise Again
If you decide to stop taking hepatoprotective medications like liver安能 (Hepatoprotective medicine) and notice a rise in liver enzymes, it is essential to consult your healthcare provider promptly. They may recommend:
- Re-evaluating Treatment: Depending on your liver function tests and overall health, your doctor may suggest resuming medication or considering alternative antiviral therapies if necessary.

- Lifestyle Adjustments: Implementing the lifestyle changes mentioned above can help mitigate liver damage and improve overall liver health.

- Consideration of Other Medications: If hepatoprotective medications are not effective or suitable, your doctor may explore other options, such as antiviral medications specifically targeting hepatitis B.


Differences Between Individuals with and Without Hepatitis B
The primary difference between individuals with elevated liver enzymes due to hepatitis B and those without the virus lies in the underlying cause of liver inflammation. In hepatitis B patients, the liver damage is often due to the viral infection itself, leading to chronic inflammation and potential fibrosis. In contrast, individuals without hepatitis B may experience elevated liver enzymes due to factors like fatty liver disease, alcohol consumption, or other liver conditions.


Conclusion
In summary, managing liver health, particularly for those with hepatitis B, involves a combination of medication, lifestyle changes, and regular monitoring. While hepatoprotective medications can be beneficial, they are not the sole solution. A holistic approach that includes dietary modifications, exercise, and avoiding harmful substances is vital for maintaining liver health. Always consult with your healthcare provider before making any changes to your treatment plan or lifestyle, especially when dealing with chronic liver conditions.

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