Numbness in Hands and Feet During Heat and Illness - Rare Disease

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I would like to ask about the issues of hand and foot numbness?


Hello, I would like to ask a question.
My body seems to have a strange reaction; whenever I exercise under the hot sun, I experience numbness in my hands and feet, particularly in the fingertips.
This sensation becomes more severe when I have a cold or fever, causing me to feel weak all over.
I have undergone a sympathetic skin response test, and the doctor mentioned that my reaction to temperature changes is delayed, which could explain the numbness.
Is this true? Have you encountered similar cases? Is there a way to completely resolve this issue? I would greatly appreciate your response.
Additionally, my skin is very dry, and I have difficulty sweating; only my nose and armpits sweat a little, while other areas do not sweat at all.
Could this affect the numbness in my hands and feet?

Xiao Wan Zi, 20~29 year old female. Ask Date: 2004/04/17

Dr. Chen Shunsheng reply Rare Disease


Exercising under the hot sun can lead to numbness in the fingertips and toes, which becomes more severe during fever.
This is likely due to temperature sensitivity polyneuropathy.
The abnormal proteins produced during heat exposure, particularly pyrogenic abnormal proteins (pyoproteins), damage the nerve myelin sheath.
It is advisable to consult a neurologist, preferably one specializing in neuromuscular disorders, for neurological examinations, electrophysiological studies, and neuroimmunological assessments to diagnose the underlying cause of the pyrogenic proteins and discuss treatment options.
In cases of abnormal protein polyneuropathy, sympathetic skin response tests may show abnormalities, while results may be normal at room temperature.
Responses to cold and heat may exhibit similar patterns.
Dry skin and difficulty sweating can also be associated symptoms.

Reply Date: 2004/04/17

More Info


Numbness in the hands and feet, especially during heat exposure or illness, can be a concerning symptom that warrants further investigation. Your description suggests a possible connection between your body's response to temperature changes and the numbness you experience.
When you exercise in hot weather, your body undergoes various physiological changes. Blood vessels dilate to help dissipate heat, and blood flow is redirected to the skin. If you have a delayed response to temperature changes, as indicated by your previous sympathetic nerve response test, this could lead to inadequate blood flow to your extremities, resulting in numbness or tingling sensations. This phenomenon is often referred to as peripheral neuropathy, which can be exacerbated by heat and illness.

Additionally, the fact that you experience increased numbness during illness, such as a cold or fever, suggests that your immune response may also play a role. During an infection, your body releases inflammatory mediators that can affect nerve function and lead to sensations of numbness or weakness. This is particularly true if you are experiencing systemic symptoms like fatigue and malaise, which can accompany viral or bacterial infections.

Your mention of having dry skin and difficulty sweating could also contribute to your symptoms. The inability to sweat effectively can lead to overheating, which may exacerbate feelings of numbness and weakness. When the body overheats, it can lead to a condition known as heat exhaustion, which can cause symptoms such as dizziness, weakness, and numbness in the extremities.
In terms of treatment, addressing the underlying causes of your symptoms is crucial. Here are some recommendations:
1. Hydration: Ensure you are well-hydrated, especially when exercising in hot weather. Dehydration can worsen symptoms of numbness and fatigue.

2. Cooling Measures: When exercising in the heat, take breaks in a cooler environment, and consider wearing moisture-wicking clothing to help regulate your body temperature.

3. Medical Evaluation: Since you have a history of numbness and a delayed response to temperature changes, it would be beneficial to consult a neurologist or a specialist in peripheral nerve disorders. They may recommend further testing, such as nerve conduction studies or imaging, to rule out any underlying conditions.

4. Physical Therapy: Engaging in physical therapy may help improve circulation and nerve function in your extremities. A therapist can provide exercises tailored to your needs.

5. Skin Care: Addressing your dry skin may also help improve your overall comfort and potentially your sweating response. Consider using moisturizers and consult a dermatologist if necessary.

6. Monitoring Symptoms: Keep a detailed log of your symptoms, including when they occur, their duration, and any associated factors (like heat exposure or illness). This information can be invaluable for your healthcare provider in diagnosing and treating your condition.

In conclusion, while your symptoms may be related to your body's response to heat and illness, a thorough medical evaluation is essential to rule out any serious underlying conditions. With appropriate management and lifestyle adjustments, many individuals can find relief from their symptoms and improve their quality of life.

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