Abnormal Health Check Results: Key Concerns and Next Steps - Family Medicine

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Hello, recently the company arranged for a health check-up, and the results showed several abnormalities.
I would like to ask:
1.
Elevated creatine phosphokinase (CPK) levels, what does this abnormality indicate? What impact does it have on the body? What symptoms may appear?

2.
Positive Helicobacter pylori antibody, I have heard that this is a high-risk factor for stomach cancer, is that correct? Is further follow-up necessary? Is this serious?

3.
Elevated triiodothyronine (T3) levels with normal thyroxine (T4) levels, what impact does this have on the body? What symptoms may appear?

4.
In the urine analysis, the specific gravity is low, what does this abnormality indicate? What impact does it have on the body? What symptoms may appear?
I appreciate your assistance in answering these questions.
Thank you!

tian, 30~39 year old female. Ask Date: 2004/04/25

Dr. Lin Mingxing reply Family Medicine


Dr.
Lin Ming-Hsing from Tainan Hospital of the Department of Health Executive Yuan responded: 1) Elevated CPK levels are mostly due to muscle overexertion (from exercise or excessive labor), which causes muscle cell damage and the release of CPK.
Additionally, some elevations in CPK levels are associated with myocardial infarction.
2) This is a statistical advantage; typically, there is a tendency to fear chronic gastritis, which may be addressed by improving dietary and lifestyle habits for better health.
3) This condition also falls under hyperthyroid function; please consult an endocrinologist for a detailed examination of the thyroid gland or the immune system.
Tainan Hospital wishes you good health and all the best.

Reply Date: 2004/04/25

More Info


Hello! Thank you for reaching out with your health check results. Let's break down your concerns regarding the abnormal findings from your recent health examination.

1. Elevated Creatine Phosphokinase (CPK): CPK is an enzyme found in the heart, brain, and skeletal muscles. Elevated levels can indicate muscle damage, which may occur due to various reasons such as intense exercise, muscle injury, or conditions like rhabdomyolysis. Symptoms of elevated CPK can include muscle pain, weakness, and swelling. In some cases, it may indicate more serious conditions like heart attacks or muscular dystrophies. It’s essential to correlate this finding with any symptoms you may be experiencing and possibly follow up with a healthcare provider for further evaluation, including a physical examination and possibly additional tests.

2. Positive Helicobacter pylori Antibodies: The presence of antibodies against H. pylori suggests a current or past infection with this bacterium, which is known to be associated with peptic ulcers and is a risk factor for gastric cancer. While not everyone infected with H. pylori will develop cancer, it is indeed considered a high-risk factor. It is advisable to follow up with a gastroenterologist, who may recommend further testing, such as a breath test, stool test, or endoscopy, to assess the extent of the infection and determine the appropriate treatment, which may include antibiotics and proton pump inhibitors.

3. Elevated Triiodothyronine (T3) with Normal Thyroxine (T4): T3 is a thyroid hormone that plays a crucial role in metabolism. An elevated T3 level, especially with normal T4, could indicate conditions such as hyperthyroidism or thyroiditis. Symptoms of hyperthyroidism can include weight loss, increased heart rate, anxiety, tremors, and heat intolerance. It’s important to consult with an endocrinologist for a comprehensive evaluation, which may include additional thyroid function tests and imaging studies to determine the underlying cause and appropriate management.

4. Low Urine Specific Gravity: A low urine specific gravity indicates dilute urine, which can occur due to various reasons, including excessive fluid intake, diabetes insipidus, or kidney issues. Symptoms may include increased urination and thirst. It’s important to assess this finding in the context of your overall health and hydration status. If you have symptoms like excessive thirst or urination, or if there are concerns about kidney function, further evaluation by a nephrologist may be warranted.


Next Steps:
- Follow-Up Appointments: Schedule appointments with relevant specialists (e.g., a cardiologist for CPK, a gastroenterologist for H. pylori, an endocrinologist for thyroid issues, and a nephrologist for urine concerns).

- Further Testing: Be prepared for additional tests that may be recommended based on your initial findings.

- Monitor Symptoms: Keep track of any symptoms you may experience and report these to your healthcare provider.

- Lifestyle Considerations: Depending on the findings, consider lifestyle modifications such as diet changes, hydration, and exercise, as advised by your healthcare providers.

In summary, while some of these findings may be concerning, many can be managed effectively with appropriate follow-up and treatment. It’s essential to take these results seriously and work closely with your healthcare team to ensure your health is monitored and managed properly. Thank you for your questions, and I wish you the best in your health journey!

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