Managing Post-Stroke Tremors: Insights and Treatment Options - Neurology

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Tremors in the left hand after a cerebellar stroke?


Hello Dr.
Tsao: My mother suffered a hemorrhagic stroke in the left cerebellum in May, and her left side has been quite inconvenient since then.
She is currently undergoing rehabilitation and receiving medication treatment.
On August 1, she was hospitalized due to low blood pressure and loss of consciousness, and her antihypertensive medication was adjusted.
The cardiologist discontinued the tremor medication Inderal that was prescribed by the neurosurgeon, and after stopping Natrilix, switched to Adalat, Aceltil, and the lipid-lowering medication Lipitor.
The cerebral circulation medication Nootropil and another medication Longcardio were retained.
Additionally, since my mother occasionally experiences insomnia, a psychiatrist was consulted, who prescribed the antidepressant Kinloft and the sleeping pill Stilnox.
However, after taking the antidepressant, my mother experienced increased tremors, and since she has been able to manage her emotions well despite the stress of her illness, she stopped taking it.
On August 8, my mother again experienced dizziness due to low blood pressure.
On August 11, due to her tremors making rehabilitation difficult, she visited a neurologist, who prescribed the anticonvulsant Rivotril.
However, after taking it, she experienced fecal incontinence at 3 AM on August 12, which had not been an issue previously.
My questions are:
1.
My mother has experienced several episodes of loss of consciousness due to low blood pressure, all occurring in the evening, some time after taking her morning antihypertensive medication.
Why do these episodes occur in the evening? While antihypertensive medication may be a factor, could there be other issues at play, such as a dissolving blood clot in the brain? Is this common for stroke patients? At what level of consciousness loss is it considered dangerous? Is there a timeframe within which regaining consciousness indicates it is not dangerous? (Note: the hemorrhage site is between the cerebellum and the brainstem.) The cardiologist has now switched Adalat to Syscor.
2.
If my mother does not take the tremor medication, will it have any consequences? Will the tremors disappear once the blood clot is absorbed? Also, is the tremor in her left hand indicative of epilepsy? Although my mother has shown a somewhat expressionless face and drooling after the stroke, her thinking remains agile and her memory is intact.
Currently, she is trying to overcome balance issues, but doesn’t Rivotril have side effects that could lead to imbalance? While Inderal may cause a decrease in heart rate, are there no other medications besides Rivotril that can help with tremors? How effective is Inderal for tremors? Can Longcardio help with tremors?
3.
Could occasional insomnia be due to a deficiency of certain substances in the brain following the injury? Could insomnia be a sign of depression? If antidepressants are necessary, how do general neurologists prescribe medications to mitigate the side effects of tremors? Thank you for your assistance with these questions!

jeanne, 30~39 year old female. Ask Date: 2004/08/12

Dr. Cao Wenlong reply Neurology


Jeanne: You are a caring child.
Your mother's illness has made you put in a lot of effort to seek medical help.
The best approach is to discuss with the attending physician.
When the doctor sees the patient and understands the condition firsthand, they can effectively address your concerns! Dr.
Tsao Wen-Long, Neurology Department, Tzu Chi Hospital.

Reply Date: 2004/08/12

More Info


Managing post-stroke tremors can be a complex process, especially when considering the various medications and their side effects. Your mother's situation, following a hemorrhagic stroke in the left cerebellum, presents several challenges that require careful consideration and management.

1. Understanding the Low Blood Pressure Episodes: The episodes of low blood pressure leading to fainting, particularly in the evening, could be multifactorial. It is possible that the timing of her blood pressure medications plays a role, as some antihypertensive drugs can cause a drop in blood pressure several hours after administration. Additionally, dehydration, medication side effects, or even autonomic dysfunction post-stroke could contribute to these episodes. It is crucial to monitor her blood pressure regularly and discuss with her healthcare team whether her medication regimen needs adjustment or if further investigations are warranted to rule out other causes, such as blood clots or other neurological complications.

2. Tremors and Medication Management: The tremors your mother is experiencing can be a result of several factors, including the stroke itself, medication side effects, or even anxiety. Inderal (propranolol) is often used to manage tremors, particularly essential tremors, but it can also affect heart rate. If she is experiencing worsening tremors after stopping Inderal, it may be worth discussing with her neurologist the possibility of reintroducing it or considering alternative medications. Rivotril (clonazepam), while effective for certain types of tremors, can indeed cause sedation and balance issues, which may not be ideal for her rehabilitation efforts. It’s essential to have a tailored approach to her medication, weighing the benefits of tremor control against potential side effects.

3. Post-Stroke Recovery and Rehabilitation: After a stroke, recovery can be unpredictable. Tremors may improve as the brain heals, particularly if they are related to the acute phase of the stroke. However, if they persist, it may be necessary to explore other treatment options, including physical therapy, occupational therapy, and possibly other medications specifically targeting tremors. The goal of rehabilitation is to improve function and quality of life, so addressing balance issues and mobility is crucial.

4. Sleep Issues and Mental Health: Sleep disturbances can be common after a stroke and may not necessarily indicate depression. However, they can be exacerbated by anxiety or the stress of dealing with a significant health event. It’s important to evaluate her sleep patterns and consider non-pharmacological interventions, such as cognitive behavioral therapy for insomnia (CBT-I), which can be effective without the side effects associated with medications. If medication is deemed necessary, a careful selection of agents that minimize side effects while addressing her specific symptoms is critical.

5. Consultation with Specialists: Given the complexity of your mother’s condition, it may be beneficial to have a multidisciplinary approach involving her neurologist, cardiologist, and possibly a geriatrician or rehabilitation specialist. This team can collaboratively assess her medications, monitor her symptoms, and adjust her treatment plan as needed.

In summary, managing post-stroke tremors and associated symptoms requires a comprehensive approach that considers medication effects, the timing of doses, and the overall rehabilitation strategy. Regular follow-ups with her healthcare team will be essential to ensure that her treatment plan is effective and that her quality of life is optimized.

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