Do Liver Supplements Help with Fatty Liver Disease? - Gastroenterology and Hepatology

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Are liver-protective medications effective for fatty liver disease?


Hello, Dr.
Chen.
My husband has fatty liver disease, but due to work-related social obligations, he cannot avoid drinking.
I would like to ask if liver supplements containing milk thistle have any liver repair or protective functions? Additionally, he has been experiencing frequent stomach discomfort lately; could this be related to his liver condition? If he takes over-the-counter liver supplements long-term, could this put a burden on his liver? I would appreciate your answers.
Thank you!

A Yi, 30~39 year old female. Ask Date: 2004/09/08

Dr. Chen Zhiping reply Gastroenterology and Hepatology


Hello, the extract from milk thistle, known as silymarin, is commonly prescribed in clinical settings for its mild hepatoprotective effects, which can reduce inflammation.
However, this does not mean that one can continue to consume alcohol.
It is important to maintain a balanced diet, a regular lifestyle, weight loss, and exercise.
If liver function remains abnormal, please consult a hepatologist for medication and follow-up examinations.
Additionally, if you are experiencing stomach discomfort, it may be related to alcohol consumption, but it could also be due to conditions such as ulcers or gastritis.
Please seek further evaluation at a hospital.
Thank you, Dr.
Chen Zhiping!

Reply Date: 2004/09/08

More Info


Fatty liver disease, also known as hepatic steatosis, is a condition characterized by the accumulation of fat in liver cells. It can be caused by various factors, including obesity, diabetes, high cholesterol, and excessive alcohol consumption. However, in many cases, it occurs without any of these risk factors, which is referred to as non-alcoholic fatty liver disease (NAFLD).
Regarding your question about liver supplements, particularly those containing milk thistle (Silybum marianum), there is ongoing debate in the medical community about their efficacy in treating fatty liver disease. Milk thistle is often marketed as a liver tonic and is believed to have antioxidant properties that may help protect liver cells from damage. Some studies suggest that it may have a beneficial effect on liver function and could potentially help in cases of liver disease, including fatty liver. However, the evidence is not robust enough to definitively recommend it as a treatment for fatty liver disease.
It's essential to understand that while some supplements may provide mild benefits, they should not replace conventional treatment methods. The primary approach to managing fatty liver disease involves lifestyle modifications, including weight loss, dietary changes, and increased physical activity. A balanced diet low in saturated fats, sugars, and refined carbohydrates, along with regular exercise, can significantly improve liver health and reduce fat accumulation in the liver.

As for your husband's discomfort in the stomach, it could be related to his liver condition, but it may also stem from other gastrointestinal issues. The liver plays a crucial role in digestion and metabolism, so any liver dysfunction can potentially lead to digestive problems. However, it is essential to consult a healthcare professional to determine the exact cause of his symptoms.
Regarding the long-term use of over-the-counter liver supplements, caution is advised. While many supplements are marketed as "natural" and safe, they can still pose risks, especially if taken in excessive amounts or for extended periods. Some ingredients in liver supplements may interact with medications or exacerbate existing liver conditions. Therefore, it is crucial to consult with a healthcare provider before starting any new supplement, particularly for someone with a pre-existing liver condition.

In summary, while liver supplements like milk thistle may offer some benefits, they should not be relied upon as a primary treatment for fatty liver disease. The most effective way to manage this condition is through lifestyle changes, including a healthy diet and regular exercise. Additionally, any persistent symptoms, such as stomach discomfort, should be evaluated by a healthcare professional to rule out any serious underlying issues. Regular monitoring of liver function through blood tests and imaging studies is also essential for managing fatty liver disease effectively.

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