Abnormal Urinalysis Results: What They Mean for Your Health - Internal Medicine

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In the health check report


I recently had a health check-up, and there were several abnormal findings in my urine report.
I would like the physician to clarify the following: (1) My specific gravity was 1.031, which is elevated, as the reference range is 1.015 to 1.030.
(2) The qualitative protein test showed a positive result (+), while the reference value is negative (-).
When I asked the nursing staff, they mentioned it could be a testing error, and they typically only suspect issues if the result is strongly positive (2+), while mine is weakly positive (1+).
(3) My urobilinogen level was 1, whereas the reference range is 0.1 to 0.2.
My BUN and creatinine levels are normal.
What potential conditions could these three abnormal findings indicate? I am quite concerned! I would greatly appreciate the physician's insights on these three issues.
Thank you very much!

Kunhuo de ren, 20~29 year old female. Ask Date: 2004/09/24

Dr. Yang Jun reply Internal Medicine


Hello: In response to your questions, three issues were raised: First, the elevated urine specific gravity may be caused by urine concentration; second, the presence of a positive protein reaction could indicate kidney disease or a transient response during a urinary tract infection, necessitating a repeat urine test to confirm if it persists; third, elevated urobilinogen levels may suggest liver dysfunction, requiring liver function tests for a definitive diagnosis.
Therefore, it is essential to re-examine the urine in conjunction with clinical signs, and a final diagnosis should be made by a nephrologist.

Reply Date: 2004/09/24

More Info


Understanding abnormal urinalysis results can be quite concerning, especially when they deviate from the normal ranges. Let's break down the specific findings you've mentioned and their potential implications for your health.

1. Specific Gravity (SG) of 1.031: The specific gravity of urine measures the concentration of solutes in the urine. Normal values typically range from 1.015 to 1.030. A value of 1.031 is slightly elevated, which may indicate concentrated urine. This can occur due to dehydration, where your body is conserving water, or it could be a response to conditions such as diabetes mellitus or kidney issues. If you have been experiencing symptoms like increased thirst or urination, it would be wise to consult a healthcare provider for further evaluation.

2. Proteinuria (+): The presence of protein in urine (proteinuria) is not normal, as the reference value is negative. While a trace amount of protein can sometimes be seen in healthy individuals, a positive result suggests that there may be an underlying issue. This could range from benign conditions, such as temporary proteinuria due to stress, exercise, or dehydration, to more serious conditions like kidney disease, hypertension, or diabetes. The fact that your result is only +1 (as opposed to +2 or +3) is somewhat reassuring, but it still warrants further investigation, especially if you have risk factors for kidney disease.

3. Urobilinogen of 1 (normal range 0.1-0.2): Urobilinogen is a byproduct of bilirubin reduction and is typically present in small amounts in urine. An elevated level can indicate liver dysfunction, hemolysis (breakdown of red blood cells), or issues with bile flow. Since your BUN (Blood Urea Nitrogen) and creatinine levels are normal, this may suggest that your kidneys are functioning well, but the elevated urobilinogen could still point to liver-related issues or hemolytic conditions. It would be prudent to follow up with liver function tests or a complete metabolic panel.


Potential Implications and Next Steps
Given these findings, it is essential to consider the following:
- Hydration Status: Ensure you are adequately hydrated, as dehydration can lead to concentrated urine and elevated specific gravity. Drinking enough fluids can help dilute the urine and may normalize the specific gravity.

- Further Testing: Since you have proteinuria and elevated urobilinogen, it would be wise to follow up with your healthcare provider. They may recommend additional tests, such as a 24-hour urine collection for protein, kidney function tests, or liver function tests, to get a clearer picture of your health status.

- Monitoring Symptoms: Pay attention to any symptoms you may be experiencing, such as fatigue, jaundice (yellowing of the skin or eyes), changes in urination patterns, or swelling in the legs or abdomen. These symptoms can provide important clues about your overall health.

- Lifestyle Factors: Consider your diet, exercise, and any medications you may be taking, as these can influence urinalysis results. For instance, high protein intake can lead to transient proteinuria.

In conclusion, while some of your urinalysis results are concerning, they do not necessarily indicate a severe health issue. However, it is crucial to follow up with your healthcare provider for a comprehensive evaluation and to discuss any necessary lifestyle changes or further testing. Early detection and management of potential issues can significantly improve health outcomes.

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