Can kidney stones cause fluctuations in diabetes?
Hello: My grandmother has been unwell recently; she is a dementia patient with a long history of diabetes.
After being hospitalized for examination and treatment, it was found that her kidney function was poor, with stones in both kidneys and hydronephrosis.
Blood tests showed elevated white blood cell counts and she had a fever.
Both of her feet were swollen.
After a period of treatment, her kidney function has gradually improved, but her blood sugar levels remain uncontrolled.
She was transferred to the ICU on Sunday and is now receiving insulin every two hours.
I would like to ask why her blood sugar is so high? Could it be related to urinary obstruction or kidney issues?
Umy, 20~29 year old female. Ask Date: 2005/01/13
Dr. Chen Zhirong reply Urology
For diabetic patients with weakened immunity, infections are already difficult to manage.
If they also have kidney stones and urinary tract obstruction, controlling the infection becomes even more challenging.
Reply Date: 2005/01/13
More Info
Kidney stones can indeed have an indirect impact on diabetes management, particularly in patients with pre-existing conditions such as diabetes mellitus (DM). In your grandmother's case, the presence of kidney stones, along with her history of diabetes and other complications, can contribute to fluctuations in blood glucose levels for several reasons.
Firstly, kidney stones can lead to urinary obstruction, which may cause kidney dysfunction. When the kidneys are not functioning optimally, they may struggle to filter blood effectively. This can lead to an accumulation of waste products in the bloodstream, including glucose, which can exacerbate hyperglycemia (high blood sugar levels). In patients with diabetes, the kidneys play a crucial role in glucose homeostasis. If kidney function is impaired, it can lead to difficulties in managing blood sugar levels, making it harder to achieve glycemic control.
Moreover, infections are common in patients with kidney stones, especially if there is an obstruction. The presence of stones can create a breeding ground for bacteria, leading to urinary tract infections (UTIs) or pyelonephritis (kidney infection). Infections can trigger the release of stress hormones like cortisol and adrenaline, which can raise blood sugar levels. This is particularly concerning for diabetic patients, as their ability to manage blood sugar may already be compromised. Elevated white blood cell counts and fever, as noted in your grandmother's case, are indicative of an infection, which could further complicate her diabetes management.
Additionally, the stress of hospitalization and the acute illness itself can lead to increased insulin resistance. When the body is under stress, it releases counter-regulatory hormones that can raise blood glucose levels. This physiological response can make it challenging to maintain stable blood sugar levels, necessitating more frequent insulin administration, as you mentioned.
In terms of dietary considerations, while your grandmother has been mindful of her diet due to her diabetes, it is essential to ensure that her nutritional intake supports both her diabetes management and kidney health. A diet low in sodium, phosphorus, and potassium may be recommended, along with adequate hydration to help prevent further stone formation. However, it is crucial to work with a healthcare provider or a registered dietitian to tailor a diet plan that meets her specific needs, especially considering her diabetes and kidney issues.
In summary, kidney stones can contribute to fluctuations in diabetes management through mechanisms such as impaired kidney function, infections, and stress responses. It is vital for her healthcare team to monitor her kidney function closely and adjust her diabetes management plan accordingly. Regular follow-ups with both her endocrinologist and nephrologist will be crucial in ensuring that her diabetes and kidney health are managed effectively.
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